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3AH8
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BU of 3ah8 by Molmil
Structure of heterotrimeric G protein Galpha-q beta gamma in complex with an inhibitor YM-254890
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Nishimura, A, Kitano, K, Takasaki, J, Taniguchi, M, Mizuno, N, Tago, K, Hakoshima, T, Itoh, H.
Deposit date:2010-04-20
Release date:2010-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.
Proc.Natl.Acad.Sci.USA, 107, 2010
8GZ6
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BU of 8gz6 by Molmil
Crystal structure of neutralizing VHH P17 in complex with SARS-CoV-2 Alpha variant spike receptor-binding domain
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Nanobody P17
Authors:Yamaguchi, K, Anzai, I, Maeda, R, Moriguchi, M, Watanabe, T, Imura, A, Takaori-Kondo, A, Inoue, T.
Deposit date:2022-09-25
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insights into the rational design of a nanobody that binds with high affinity to the SARS-CoV-2 spike variant.
J.Biochem., 173, 2023
8GZ5
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BU of 8gz5 by Molmil
Crystal structure of neutralizing VHH P17 in complex with SARS-CoV-2 Alpha variant spike receptor-binding domain
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody P17, ...
Authors:Yamaguchi, K, Anzai, I, Maeda, R, Moriguchi, M, Watanabe, T, Imura, A, Takaori-Kondo, A, Inoue, T.
Deposit date:2022-09-25
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the rational design of a nanobody that binds with high affinity to the SARS-CoV-2 spike variant.
J.Biochem., 173, 2023
7VQ0
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BU of 7vq0 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike protein (2-up RBD) bound to neutralizing nanobodies P86
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Maeda, R, Fujita, J, Konishi, Y, Kazuma, Y, Yamazaki, H, Anzai, I, Yamaguchi, K, Kasai, K, Nagata, K, Yamaoka, Y, Miyakawa, K, Ryo, A, Shirakawa, K, Makino, F, Matsuura, Y, Inoue, T, Imura, A, Namba, K, Takaori-Kondo, A.
Deposit date:2021-10-18
Release date:2022-07-20
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron.
Commun Biol, 5, 2022
7VPY
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BU of 7vpy by Molmil
Crystal structure of the neutralizing nanobody P86 against SARS-CoV-2
Descriptor: 1,2-ETHANEDIOL, Nanobody, SULFATE ION
Authors:Maeda, R, Fujita, J, Konishi, Y, Kazuma, Y, Yamazaki, H, Anzai, I, Yamaguchi, K, Kasai, K, Nagata, K, Yamaoka, Y, Miyakawa, K, Ryo, A, Shirakawa, K, Makino, F, Matsuura, Y, Inoue, T, Imura, A, Namba, K, Takaori-Kondo, A.
Deposit date:2021-10-18
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron.
Commun Biol, 5, 2022
8WX5
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BU of 8wx5 by Molmil
Cryo-EM structure of human SLC15A4 in complex with TASL (inward-facing open)
Descriptor: Solute carrier family 15 member 4, TASL (TASL-SLC15A4 fusion protein)
Authors:Ohto, U, Zhang, Z, Fujimura, A, Shimizu, T.
Deposit date:2023-10-27
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Cryo-EM structure of human SLC15A4 in complex with TASL (inward-facing open)
To Be Published
7C26
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BU of 7c26 by Molmil
Glycosidase Wild Type at pH4.5
Descriptor: AMMONIUM ION, CITRIC ACID, GLYCEROL, ...
Authors:Tagami, T, Kikuchi, A, Okuyama, M, Kimura, A.
Deposit date:2020-05-07
Release date:2021-05-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
7C27
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BU of 7c27 by Molmil
Glycosidase F290Y at pH4.5
Descriptor: AMMONIUM ION, CITRIC ACID, GLYCEROL, ...
Authors:Tagami, T, Kikuchi, A, Okuyama, M, Kimura, A.
Deposit date:2020-05-07
Release date:2021-05-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
7C24
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BU of 7c24 by Molmil
Glycosidase F290Y at pH8.0
Descriptor: AMMONIUM ION, GLYCEROL, Isomaltose glucohydrolase
Authors:Tagami, T, Kikuchi, A, Okuyama, M, Kimura, A.
Deposit date:2020-05-07
Release date:2021-05-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
7C25
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BU of 7c25 by Molmil
Glycosidase Wild Type at pH8.0
Descriptor: AMMONIUM ION, CITRIC ACID, GLYCEROL, ...
Authors:Tagami, T, Kikuchi, A, Okuyama, M, Kimura, A.
Deposit date:2020-05-07
Release date:2021-05-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.505 Å)
Cite:Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
7EAY
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BU of 7eay by Molmil
DNA containing Cu(II)-mediated 4-N-carboxymethylcytosine base pairs
Descriptor: COBALT (II) ION, COBALT HEXAMMINE(III), COPPER (II) ION, ...
Authors:Kondo, J, Terashima, A, Yoshimura, A, Tada, Y, Ono, A.
Deposit date:2021-03-08
Release date:2022-03-09
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNA containing Cu(II)-mediated 4-N-carboxymethylcytosine base pairs
To Be Published
4JIE
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BU of 4jie by Molmil
Structural analysis and insights into glycon specificity of the rice GH1 Os7BGlu26 beta-D-mannosidase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-mannosidase/beta-glucosidase, GLYCEROL, ...
Authors:Tankrathok, A, Luang, S, Robinson, R.C, Kimura, A, Hrmova, M, Ketudat Cairns, J.R.
Deposit date:2013-03-05
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural analysis and insights into the glycon specificity of the rice GH1 Os7BGlu26 beta-D-mannosidase
Acta Crystallogr.,Sect.D, 69, 2013
3WNP
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BU of 3wnp by Molmil
D308A, F268V, D469Y, A513V, and Y515S quintuple mutant of Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase complexed with isomaltoundecaose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Cycloisomaltooligosaccharide glucanotransferase, ...
Authors:Suzuki, R, Suzuki, N, Fujimoto, Z, Momma, M, Kimura, K, Kitamura, S, Kimura, A, Funane, K.
Deposit date:2013-12-10
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular engineering of cycloisomaltooligosaccharide glucanotransferase from Bacillus circulans T-3040: structural determinants for the reaction product size and reactivity.
Biochem.J., 467, 2015
4JHO
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BU of 4jho by Molmil
Structural analysis and insights into glycon specificity of the rice GH1 Os7BGlu26 beta-D-mannosidase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-mannosidase/beta-glucosidase, GLYCEROL
Authors:Tankrathok, A, Luang, S, Robinson, R.C, Kimura, A, Hrmova, M, Ketudat Cairns, J.R.
Deposit date:2013-03-05
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural analysis and insights into the glycon specificity of the rice GH1 Os7BGlu26 beta-D-mannosidase
Acta Crystallogr.,Sect.D, 69, 2013
5E1Q
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BU of 5e1q by Molmil
Mutant (D415G) GH97 alpha-galactosidase in complex with Gal-Lac
Descriptor: CALCIUM ION, GLYCEROL, Retaining alpha-galactosidase, ...
Authors:Matsunaga, K, Yamashita, K, Tagami, T, Yao, M, Okuyama, M, Kimura, A.
Deposit date:2015-09-30
Release date:2016-10-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.943 Å)
Cite:Efficient synthesis of alpha-galactosyl oligosaccharides using a mutant Bacteroides thetaiotaomicron retaining alpha-galactosidase (BtGH97b).
FEBS J., 284, 2017
3WNM
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BU of 3wnm by Molmil
D308A mutant of Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase complexed with isomaltoheptaose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Cycloisomaltooligosaccharide glucanotransferase, ...
Authors:Suzuki, N, Fujimoto, Z, Kim, Y.M, Momma, M, Kishine, N, Suzuki, R, Suzuki, S, Kitamura, S, Kobayashi, M, Kimura, A, Funane, K.
Deposit date:2013-12-10
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural elucidation of the cyclization mechanism of alpha-1,6-glucan by Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase.
J.Biol.Chem., 289, 2014
3WNK
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BU of 3wnk by Molmil
Crystal Structure of Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase
Descriptor: ACETATE ION, CADMIUM ION, CALCIUM ION, ...
Authors:Suzuki, N, Fujimoto, Z, Kim, Y.M, Momma, M, Kishine, N, Suzuki, R, Kobayashi, M, Kimura, A, Funane, K.
Deposit date:2013-12-10
Release date:2014-02-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural elucidation of the cyclization mechanism of alpha-1,6-glucan by Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase.
J.Biol.Chem., 289, 2014
3WNN
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BU of 3wnn by Molmil
D308A mutant of Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase complexed with isomaltooctaose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Cycloisomaltooligosaccharide glucanotransferase, ...
Authors:Suzuki, N, Fujimoto, Z, Kim, Y.M, Momma, M, Kishine, N, Suzuki, R, Suzuki, S, Kitamura, S, Kobayashi, M, Kimura, A, Funane, K.
Deposit date:2013-12-10
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural elucidation of the cyclization mechanism of alpha-1,6-glucan by Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase.
J.Biol.Chem., 289, 2014
3WNL
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BU of 3wnl by Molmil
D308A mutant of Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase complexed with isomaltohexaose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Cycloisomaltooligosaccharide glucanotransferase, ...
Authors:Suzuki, N, Fujimoto, Z, Kim, Y.M, Momma, M, Kishine, N, Suzuki, R, Suzuki, S, Kitamura, S, Kobayashi, M, Kimura, A, Funane, K.
Deposit date:2013-12-10
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural elucidation of the cyclization mechanism of alpha-1,6-glucan by Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase.
J.Biol.Chem., 289, 2014
3WNO
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BU of 3wno by Molmil
D308A mutant of Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase complexed with cycloisomaltooctaose
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Suzuki, N, Fujimoto, Z, Kim, Y.M, Momma, M, Kishine, N, Suzuki, R, Kobayashi, M, Kimura, A, Funane, K.
Deposit date:2013-12-10
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural elucidation of the cyclization mechanism of alpha-1,6-glucan by Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase.
J.Biol.Chem., 289, 2014
4Y7E
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BU of 4y7e by Molmil
Crystal structure of beta-mannanase from Streptomyces thermolilacinus with mannohexaose
Descriptor: CALCIUM ION, Endoglucanase, GLYCEROL, ...
Authors:Kumagai, Y, Yamashita, K, Okuyama, M, Hatanaka, T, Yao, M, Kimura, A.
Deposit date:2015-02-14
Release date:2015-09-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The loop structure of Actinomycete glycoside hydrolase family 5 mannanases governs substrate recognition
Febs J., 282, 2015
3KSC
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BU of 3ksc by Molmil
Crystal structure of pea prolegumin, an 11S seed globulin from Pisum sativum L.
Descriptor: GLYCEROL, LegA class, SULFATE ION
Authors:Tandang-Silvas, M.R.G, Fukuda, T, Fukuda, C, Prak, K, Cabanos, C, Kimura, A, Itoh, T, Mikami, B, Maruyama, N, Utsumi, S.
Deposit date:2009-11-21
Release date:2010-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.606 Å)
Cite:Conservation and divergence on plant seed 11S globulins based on crystal structures.
Biochim.Biophys.Acta, 1804, 2010
5X7S
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BU of 5x7s by Molmil
Crystal structure of Paenibacillus sp. 598K alpha-1,6-glucosyltransferase, terbium derivative
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Fujimoto, Z, Kishine, N, Suzuki, N, Momma, M, Ichinose, H, Kimura, A, Funane, K.
Deposit date:2017-02-27
Release date:2017-07-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Carbohydrate-binding architecture of the multi-modular alpha-1,6-glucosyltransferase from Paenibacillus sp. 598K, which produces alpha-1,6-glucosyl-alpha-glucosaccharides from starch
Biochem. J., 474, 2017
5X7Q
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BU of 5x7q by Molmil
Crystal structure of Paenibacillus sp. 598K alpha-1,6-glucosyltransferase complexed with maltohexaose
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Fujimoto, Z, Kishine, N, Suzuki, N, Momma, M, Ichinose, H, Kimura, A, Funane, K.
Deposit date:2017-02-27
Release date:2017-07-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Carbohydrate-binding architecture of the multi-modular alpha-1,6-glucosyltransferase from Paenibacillus sp. 598K, which produces alpha-1,6-glucosyl-alpha-glucosaccharides from starch
Biochem. J., 474, 2017
5X7O
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BU of 5x7o by Molmil
Crystal structure of Paenibacillus sp. 598K alpha-1,6-glucosyltransferase
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Fujimoto, Z, Suzuki, N, Kishine, N, Momma, M, Ichinose, H, Kimura, A, Funane, K.
Deposit date:2017-02-27
Release date:2017-07-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Carbohydrate-binding architecture of the multi-modular alpha-1,6-glucosyltransferase from Paenibacillus sp. 598K, which produces alpha-1,6-glucosyl-alpha-glucosaccharides from starch
Biochem. J., 474, 2017

 

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