7YRO
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![BU of 7yro by Molmil](/molmil-images/mine/7yro) | Crystal structure of mango fucosyltransferase 13 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, Fucosyltransferase, ... | Authors: | Okada, T, Teramoto, T, Ihara, H, Ikeda, Y, Kakuta, Y. | Deposit date: | 2022-08-10 | Release date: | 2023-08-16 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Crystal structure of mango alpha 1,3/ alpha 1,4-fucosyltransferase elucidates unique elements that regulate Lewis A-dominant oligosaccharide assembly. Glycobiology, 34, 2024
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5XFA
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![BU of 5xfa by Molmil](/molmil-images/mine/5xfa) | Crystal structure of NAD+-reducing [NiFe]-hydrogenase in the H2-reduced state | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ... | Authors: | Shomura, Y, Taketa, M, Nakashima, H, Tai, H, Nakagawa, H, Ikeda, Y, Ishii, M, Igarashi, Y, Nishihara, H, Yoon, K.S, Ogo, S, Hirota, S, Higuchi, Y. | Deposit date: | 2017-04-09 | Release date: | 2017-08-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of the redox switches in the NAD(+)-reducing soluble [NiFe]-hydrogenase Science, 357, 2017
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5XF9
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![BU of 5xf9 by Molmil](/molmil-images/mine/5xf9) | Crystal structure of NAD+-reducing [NiFe]-hydrogenase in the air-oxidized state | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | Authors: | Shomura, Y, Taketa, M, Nakashima, H, Tai, H, Nakagawa, H, Ikeda, Y, Ishii, M, Igarashi, Y, Nishihara, H, Yoon, K.S, Ogo, S, Hirota, S, Higuchi, Y. | Deposit date: | 2017-04-09 | Release date: | 2017-08-23 | Last modified: | 2017-09-20 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Structural basis of the redox switches in the NAD(+)-reducing soluble [NiFe]-hydrogenase Science, 357, 2017
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2ZRU
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![BU of 2zru by Molmil](/molmil-images/mine/2zru) | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN | Descriptor: | FLAVIN MONONUCLEOTIDE, Isopentenyl-diphosphate delta-isomerase | Authors: | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | Deposit date: | 2008-09-01 | Release date: | 2009-01-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. J.Biol.Chem., 284, 2009
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3A4S
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![BU of 3a4s by Molmil](/molmil-images/mine/3a4s) | The crystal structure of the SLD2:Ubc9 complex | Descriptor: | NFATC2-interacting protein, SUMO-conjugating enzyme UBC9 | Authors: | Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. | Deposit date: | 2009-07-14 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45 Proteins, 78, 2009
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2ZRZ
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![BU of 2zrz by Molmil](/molmil-images/mine/2zrz) | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with reduced FMN and DMAPP | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, DIMETHYLALLYL DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, ... | Authors: | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | Deposit date: | 2008-09-01 | Release date: | 2009-01-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. J.Biol.Chem., 284, 2009
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2ZRV
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![BU of 2zrv by Molmil](/molmil-images/mine/2zrv) | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with reduced FMN. | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, Isopentenyl-diphosphate delta-isomerase | Authors: | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | Deposit date: | 2008-09-01 | Release date: | 2009-01-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. J.Biol.Chem., 284, 2009
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2ZRY
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![BU of 2zry by Molmil](/molmil-images/mine/2zry) | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with reduced FMN and IPP. | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, ... | Authors: | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | Deposit date: | 2008-09-01 | Release date: | 2009-01-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. J.Biol.Chem., 284, 2009
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2ZRW
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![BU of 2zrw by Molmil](/molmil-images/mine/2zrw) | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN and IPP. | Descriptor: | FLAVIN MONONUCLEOTIDE, ISOPENTYL PYROPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, ... | Authors: | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | Deposit date: | 2008-09-01 | Release date: | 2009-01-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. J.Biol.Chem., 284, 2009
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3A4R
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![BU of 3a4r by Molmil](/molmil-images/mine/3a4r) | The crystal structure of SUMO-like domain 2 in Nip45 | Descriptor: | 1,2-ETHANEDIOL, NFATC2-interacting protein, SULFATE ION | Authors: | Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. | Deposit date: | 2009-07-14 | Release date: | 2010-02-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45 Proteins, 78, 2009
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2ZRX
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![BU of 2zrx by Molmil](/molmil-images/mine/2zrx) | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN and DMAPP. | Descriptor: | DIMETHYLALLYL DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, Isopentenyl-diphosphate delta-isomerase, ... | Authors: | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | Deposit date: | 2008-09-01 | Release date: | 2009-01-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. J.Biol.Chem., 284, 2009
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2DE0
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![BU of 2de0 by Molmil](/molmil-images/mine/2de0) | Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 | Descriptor: | Alpha-(1,6)-fucosyltransferase | Authors: | Taniguchi, N, Ihara, H, Nakagawa, A. | Deposit date: | 2006-02-07 | Release date: | 2006-12-26 | Last modified: | 2020-03-25 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Crystal structure of mammalian {alpha}1,6-fucosyltransferase, FUT8 Glycobiology, 17, 2007
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2JMW
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![BU of 2jmw by Molmil](/molmil-images/mine/2jmw) | Structure of DNA-Binding Domain of Arabidopsis GT-1 | Descriptor: | DNA binding protein GT-1 | Authors: | Nagata, T, Niyada, E, Noto, K, Ikeda, Y, Yamamoto, Y, Uesugi, S, Murata, J, Hiratsuka, K, Katahira, M. | Deposit date: | 2006-12-11 | Release date: | 2007-12-11 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Solution structures of the trihelix DNA-binding domains of the wild-type and a phosphomimetic mutant of Arabidopsis GT-1: mechanism for an increase in DNA-binding affinity through phosphorylation. Proteins, 78, 2010
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8GV1
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![BU of 8gv1 by Molmil](/molmil-images/mine/8gv1) | Crystal structure of anti-FX IgG fab with FAST-Ig mutations | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Anti-factor X IgG fab heavy chain, ... | Authors: | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | Deposit date: | 2022-09-14 | Release date: | 2023-06-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.186 Å) | Cite: | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
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8GV2
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![BU of 8gv2 by Molmil](/molmil-images/mine/8gv2) | Crystal structure of anti-FX IgG fab without FAST-Ig mutations | Descriptor: | 1,2-ETHANEDIOL, Anti-factor X IgG fab heavy chain, Anti-factor X IgG fab light chain | Authors: | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | Deposit date: | 2022-09-14 | Release date: | 2023-06-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.274 Å) | Cite: | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
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8GUZ
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![BU of 8guz by Molmil](/molmil-images/mine/8guz) | Crystal structure of anti-FIXa IgG fab with FAST-Ig mutations | Descriptor: | 1,2-ETHANEDIOL, Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain | Authors: | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | Deposit date: | 2022-09-14 | Release date: | 2023-06-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
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8GV0
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![BU of 8gv0 by Molmil](/molmil-images/mine/8gv0) | Crystal structure of anti-FIXa IgG fab without FAST-Ig mutations | Descriptor: | Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain | Authors: | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | Deposit date: | 2022-09-14 | Release date: | 2023-06-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.192 Å) | Cite: | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
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6K4H
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![BU of 6k4h by Molmil](/molmil-images/mine/6k4h) | Crystal structure of the PI5P4Kbeta-AMPPNP complex | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Senda, M, Senda, T. | Deposit date: | 2019-05-23 | Release date: | 2020-05-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The GTP responsiveness of PI5P4K beta evolved from a compromised trade-off between activity and specificity. Structure, 2022
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6K4G
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![BU of 6k4g by Molmil](/molmil-images/mine/6k4g) | Crystal structure of the PI5P4Kbeta-GMPPNP complex | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Senda, M, Senda, T. | Deposit date: | 2019-05-23 | Release date: | 2020-05-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The GTP responsiveness of PI5P4K beta evolved from a compromised trade-off between activity and specificity. Structure, 2022
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7WKI
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![BU of 7wki by Molmil](/molmil-images/mine/7wki) | |
5WQV
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![BU of 5wqv by Molmil](/molmil-images/mine/5wqv) | Crystal structure of PriB mutant - S55A | Descriptor: | Primosomal replication protein N | Authors: | Fujiyama, S, Shiroishi, M, Katayama, T, Abe, Y, Ueda, T. | Deposit date: | 2016-11-28 | Release date: | 2017-11-29 | Last modified: | 2019-06-12 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Insight into the interaction between PriB and DnaT on bacterial DNA replication restart: Significance of the residues on PriB dimer interface and highly acidic region on DnaT. Biochim Biophys Acta Proteins Proteom, 1867, 2019
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2EBI
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![BU of 2ebi by Molmil](/molmil-images/mine/2ebi) | Arabidopsis GT-1 DNA-binding domain with T133D phosphomimetic mutation | Descriptor: | DNA binding protein GT-1 | Authors: | Nagata, T, Noto, K, Niyada, E, Ikeda, Y, Yamamoto, Y, Uesugi, S, Murata, J, Hiratsuka, K, Katahira, M. | Deposit date: | 2007-02-08 | Release date: | 2008-02-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structures of the trihelix DNA-binding domains of the wild-type and a phosphomimetic mutant of Arabidopsis GT-1: mechanism for an increase in DNA-binding affinity through phosphorylation. Proteins, 78, 2010
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8K5H
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![BU of 8k5h by Molmil](/molmil-images/mine/8k5h) | Structure of the SARS-CoV-2 BA.1 spike with UT28-RD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Chen, L, Kita, S, Anraku, Y, Maenaka, K. | Deposit date: | 2023-07-21 | Release date: | 2023-12-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1. Structure, 32, 2024
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8K5G
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![BU of 8k5g by Molmil](/molmil-images/mine/8k5g) | Structure of the SARS-CoV-2 BA.1 RBD with UT28-RD | Descriptor: | Spike protein S1, UT28K-RD Fab Heavy chain, UT28K-RD Fab Light chain | Authors: | Chen, L, Kita, S, Anraku, Y, Maenaka, K. | Deposit date: | 2023-07-21 | Release date: | 2023-12-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1. Structure, 32, 2024
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7EM6
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![BU of 7em6 by Molmil](/molmil-images/mine/7em6) | Crystal structure of the PI5P4Kbeta N203D-ITP complex | Descriptor: | INOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, [[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(6-oxidanylidene-1~{H}-purin-9-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | Authors: | Senda, M, Senda, T. | Deposit date: | 2021-04-13 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | The GTP responsiveness of PI5P4K beta evolved from a compromised trade-off between activity and specificity. Structure, 30, 2022
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