1JB7
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5I9J
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![BU of 5i9j by Molmil](/molmil-images/mine/5i9j) | Structure of the cholesterol and lutein-binding domain of human STARD3 at 1.74A | Descriptor: | 1,2-ETHANEDIOL, L(+)-TARTARIC ACID, SULFATE ION, ... | Authors: | Horvath, M.P, Bernstein, P.S, Li, B, George, E.W, Tran, Q.T. | Deposit date: | 2016-02-20 | Release date: | 2016-03-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structure of the lutein-binding domain of human StARD3 at 1.74 angstrom resolution and model of a complex with lutein. Acta Crystallogr.,Sect.F, 72, 2016
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1OTC
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![BU of 1otc by Molmil](/molmil-images/mine/1otc) | THE O. NOVA TELOMERE END BINDING PROTEIN COMPLEXED WITH SINGLE STRAND DNA | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3'), PROTEIN (TELOMERE-BINDING PROTEIN ALPHA SUBUNIT), PROTEIN (TELOMERE-BINDING PROTEIN BETA SUBUNIT) | Authors: | Horvath, M.P, Schweiker, V.L, Bevilacqua, J.M, Ruggles, J.A, Schultz, S.C. | Deposit date: | 1998-11-25 | Release date: | 1999-04-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA. Cell(Cambridge,Mass.), 95, 1998
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2I0Q
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6Q0C
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![BU of 6q0c by Molmil](/molmil-images/mine/6q0c) | MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with undamaged dG | Descriptor: | 1,2-ETHANEDIOL, A/G-specific adenine glycosylase, CALCIUM ION, ... | Authors: | O'Shea Murray, V.L, Russelburg, L.P, Horvath, M.P, David, S.S. | Deposit date: | 2019-08-01 | Release date: | 2019-08-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY. Acs Chem.Biol., 15, 2020
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6U7T
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![BU of 6u7t by Molmil](/molmil-images/mine/6u7t) | MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G) | Descriptor: | Adenine DNA glycosylase, CALCIUM ION, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ... | Authors: | O'Shea Murray, V.L, Cao, S, Horvath, M.P, David, S.S. | Deposit date: | 2019-09-03 | Release date: | 2019-10-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY. Acs Chem.Biol., 15, 2020
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3FP6
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![BU of 3fp6 by Molmil](/molmil-images/mine/3fp6) | Anionic trypsin in complex with bovine pancreatic trypsin inhibitor (BPTI) determined to the 1.49 A resolution limit | Descriptor: | 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ... | Authors: | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2009-01-04 | Release date: | 2009-02-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structure of a serine protease poised to resynthesize a peptide bond. Proc.Natl.Acad.Sci.USA, 106, 2009
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3FP7
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![BU of 3fp7 by Molmil](/molmil-images/mine/3fp7) | Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) cleaved at the scissile bond (LYS15-ALA16) determined to the 1.46 A resolution limit | Descriptor: | 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ... | Authors: | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2009-01-04 | Release date: | 2009-02-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structure of a serine protease poised to resynthesize a peptide bond. Proc.Natl.Acad.Sci.USA, 106, 2009
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3FP8
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![BU of 3fp8 by Molmil](/molmil-images/mine/3fp8) | Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) determined to the 1.46 A resolution limit | Descriptor: | 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ... | Authors: | Zakharova, E, Horvath, M.P, Goldenberg, D.P, Curtice, K. | Deposit date: | 2009-01-04 | Release date: | 2009-02-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structure of a serine protease poised to resynthesize a peptide bond. Proc.Natl.Acad.Sci.USA, 106, 2009
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8DVP
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![BU of 8dvp by Molmil](/molmil-images/mine/8dvp) | Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with substrate purine | Descriptor: | ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ... | Authors: | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | Deposit date: | 2022-07-29 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism. Nucleic Acids Res., 51, 2023
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8DW0
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![BU of 8dw0 by Molmil](/molmil-images/mine/8dw0) | Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site (AP) product and crystallized with sodium acetate | Descriptor: | 1,2-ETHANEDIOL, Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ... | Authors: | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | Deposit date: | 2022-07-30 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism. Nucleic Acids Res., 51, 2023
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8DW7
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![BU of 8dw7 by Molmil](/molmil-images/mine/8dw7) | DNA glycosylase MutY variant N146S in complex with DNA containing the transition state analog 1N paired with d(8-oxo-G) | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ... | Authors: | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | Deposit date: | 2022-07-31 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism. Nucleic Acids Res., 51, 2023
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8DVY
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![BU of 8dvy by Molmil](/molmil-images/mine/8dvy) | DNA glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site product (AP) and crystalized with calcium acetate | Descriptor: | ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ... | Authors: | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | Deposit date: | 2022-07-30 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism. Nucleic Acids Res., 51, 2023
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8DW4
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![BU of 8dw4 by Molmil](/molmil-images/mine/8dw4) | Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an abasic site product (AP) generated by the enzyme in crystals by removal of calcium | Descriptor: | ACETATE ION, Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ... | Authors: | Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. | Deposit date: | 2022-07-31 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism. Nucleic Acids Res., 51, 2023
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8DWF
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![BU of 8dwf by Molmil](/molmil-images/mine/8dwf) | Glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with substrate adenine | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ... | Authors: | Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P. | Deposit date: | 2022-08-01 | Release date: | 2023-08-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY To Be Published
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8DWD
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![BU of 8dwd by Molmil](/molmil-images/mine/8dwd) | Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine | Descriptor: | ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ... | Authors: | Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P. | Deposit date: | 2022-08-01 | Release date: | 2023-08-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY To Be Published
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8DWE
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![BU of 8dwe by Molmil](/molmil-images/mine/8dwe) | Adenine glycosylase MutY variant E43Q in complex with DNA containing d(8-oxo-G) paired with substrate purine | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ... | Authors: | Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P. | Deposit date: | 2022-08-01 | Release date: | 2023-08-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY To Be Published
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1Y62
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![BU of 1y62 by Molmil](/molmil-images/mine/1y62) | A 2.4 crystal structure of conkunitzin-S1, a novel Kunitz-fold cone snail neurotoxin. | Descriptor: | Conkunitzin-S1, SULFATE ION | Authors: | Dy, C.Y, Buczek, P, Horvath, M.P. | Deposit date: | 2004-12-03 | Release date: | 2005-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of conkunitzin-S1, a neurotoxin and Kunitz-fold disulfide variant from cone snail. Acta Crystallogr.,Sect.D, 62, 2006
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2FI4
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![BU of 2fi4 by Molmil](/molmil-images/mine/2fi4) | Crystal structure of a BPTI variant (Cys14->Ser) in complex with trypsin | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2005-12-27 | Release date: | 2006-01-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor. J.Mol.Biol., 382, 2008
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2FI3
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![BU of 2fi3 by Molmil](/molmil-images/mine/2fi3) | Crystal structure of a BPTI variant (Cys14->Ser, Cys38->Ser) in complex with trypsin | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2005-12-27 | Release date: | 2006-01-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor. J.Mol.Biol., 382, 2008
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2FI5
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![BU of 2fi5 by Molmil](/molmil-images/mine/2fi5) | Crystal structure of a BPTI variant (Cys38->Ser) in complex with trypsin | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2005-12-27 | Release date: | 2006-01-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor. J.Mol.Biol., 382, 2008
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2FTL
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![BU of 2ftl by Molmil](/molmil-images/mine/2ftl) | Crystal structure of trypsin complexed with BPTI at 100K | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Hanson, W.M, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2006-01-24 | Release date: | 2006-02-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin. J.Mol.Biol., 366, 2007
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2FTM
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![BU of 2ftm by Molmil](/molmil-images/mine/2ftm) | Crystal structure of trypsin complexed with the BPTI variant (Tyr35->Gly) | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Hanson, W.M, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2006-01-24 | Release date: | 2006-02-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin. J.Mol.Biol., 366, 2007
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2M7R
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![BU of 2m7r by Molmil](/molmil-images/mine/2m7r) | Nmda receptor antagonist, conantokin bk-b, nmr, 20 structure | Descriptor: | CONANTOKIN BK-B | Authors: | Curtice, K.J, Platt, R.J, Skalicky, J.J, Horvath, M.P, Twede, V.D. | Deposit date: | 2013-04-29 | Release date: | 2014-02-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | From molecular phylogeny towards differentiating pharmacology for NMDA receptor subtypes. Toxicon, 81C, 2014
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8FAY
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![BU of 8fay by Molmil](/molmil-images/mine/8fay) | Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G) | Descriptor: | Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*CP*AP*(NR1)P*GP*TP*CP*T)-3'), ... | Authors: | Trasvina-Arenas, C.H, Lin, W.J, Demir, M, Fisher, A.J, David, S.S, Horvath, M.P. | Deposit date: | 2022-11-29 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G) To Be Published
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