8JQZ
 
 | | Crystal Structure of GppNHp-bound mIRGB10 | | Descriptor: | Immunity-related GTPase family member b10, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Ha, H.J, Park, H.H. | | Deposit date: | 2023-06-15 | | Release date: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Structural basis of IRGB10 oligomerization by GTP hydrolysis.
Front Immunol, 14, 2023
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8JQY
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7C3K
 | | Crystal Structure of mIRGB10 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Immunity-related GTPase family member b10 | | Authors: | Ha, H.J, Jeong, J.H, Kim, Y.G, Park, H.H. | | Deposit date: | 2020-05-12 | | Release date: | 2021-04-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Molecular basis of IRGB10 oligomerization and membrane association for pathogen membrane disruption.
Commun Biol, 4, 2021
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7BSO
 | | Crystal structure of the human NLRP9 pyrin domain | | Descriptor: | NACHT, LRR and PYD domains-containing protein 9 | | Authors: | Park, H.H, Ha, H.J. | | Deposit date: | 2020-03-31 | | Release date: | 2021-02-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Crystal structure of the human NLRP9 pyrin domain reveals a bent N-terminal loop that may regulate inflammasome assembly.
Febs Lett., 594, 2020
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6A8P
 | | Transglutaminase 2 mutant G224V in complex with GTP | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase 2 | | Authors: | Park, H.H, Ha, H.J, Kwon, S. | | Deposit date: | 2018-07-09 | | Release date: | 2018-09-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.537 Å) | | Cite: | Structure of natural variant transglutaminase 2 reveals molecular basis of gaining stability and higher activity.
PLoS ONE, 13, 2018
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6KU5
 | | Notothenia coriiceps TRAF5 | | Descriptor: | TRAF5 | | Authors: | Park, H.H, Kim, C.M. | | Deposit date: | 2019-08-30 | | Release date: | 2020-07-08 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.299 Å) | | Cite: | Structural and biochemical characterization of TRAF5 from Notothenia coriiceps and its implications in fish immune cell signaling.
Fish Shellfish Immunol., 102, 2020
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7V6E
 | | DREP3 | | Descriptor: | DNAation factor-related protein 3, isoform A | | Authors: | Lee, S.Y, Park, H.H. | | Deposit date: | 2021-08-20 | | Release date: | 2022-08-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Helical filament structure of the DREP3 CIDE domain reveals a unified mechanism of CIDE-domain assembly.
Acta Crystallogr D Struct Biol, 77, 2021
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8ZEY
 | | Anti-CRISPR type I subtype E3;AcrIE3 | | Descriptor: | AcrIE3 | | Authors: | Kim, D.Y, Park, H.H. | | Deposit date: | 2024-05-07 | | Release date: | 2024-06-05 | | Last modified: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (1.734 Å) | | Cite: | Novel structure of the anti-CRISPR protein AcrIE3 and its implication on the CRISPR-Cas inhibition.
Biochem.Biophys.Res.Commun., 722, 2024
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7CM0
 | | Crystal structure of a glutaminyl cyclase in complex with NHV-1009 | | Descriptor: | 1-(cyclopentylmethyl)-1-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea, Glutaminyl-peptide cyclotransferase, ZINC ION | | Authors: | Lee, J.W, Song, J.Y, Jang, T.H, Ha, J.H. | | Deposit date: | 2020-07-23 | | Release date: | 2021-12-22 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design.
Eur.J.Med.Chem., 226, 2021
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8HJJ
 | | Anti-CRISPR protein AcrIC9 | | Descriptor: | Anti-CRISPR protein Type I-C9 | | Authors: | Kang, Y.J, Park, H.H. | | Deposit date: | 2022-11-23 | | Release date: | 2023-09-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structure of AcrIC9 revealing the putative inhibitory mechanism of AcrIC9 against the type IC CRISPR-Cas system.
Iucrj, 10, 2023
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8IWL
 | | A.baumannii Uncharacterized sugar kinase ydjH | | Descriptor: | Uncharacterized sugar kinase YdjH | | Authors: | Lee, G.H, Park, H.H. | | Deposit date: | 2023-03-30 | | Release date: | 2023-05-24 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (3.04 Å) | | Cite: | Structure of YdjH from Acinetobacter baumannii revealed an active site of YdjH family sugar kinase.
Biochem.Biophys.Res.Commun., 664, 2023
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7VPF
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5JYN
 | | Structure of the transmembrane domain of HIV-1 gp41 in bicelle | | Descriptor: | Envelope glycoprotein gp160 | | Authors: | Dev, J, Fu, Q, Park, D, Chen, B, Chou, J.J. | | Deposit date: | 2016-05-14 | | Release date: | 2016-06-29 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis for membrane anchoring of HIV-1 envelope spike.
Science, 353, 2016
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7CP1
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7D27
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6UJV
 | | Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail (LLP2) | | Descriptor: | Envelope glycoprotein GP41 | | Authors: | Piai, A, Fu, Q, Cai, Y, Ghantous, F, Xiao, T, Shaik, M.M, Peng, H, Rits-Volloch, S, Liu, Z, Chen, W, Seaman, M.S, Chen, B, Chou, J.J. | | Deposit date: | 2019-10-03 | | Release date: | 2020-05-13 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein.
Nat Commun, 11, 2020
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6K8H
 | | Crystal structure of an omega-transaminase from Sphaerobacter thermophilus | | Descriptor: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Aminotransferase class-III | | Authors: | Park, H.H, Kwon, S. | | Deposit date: | 2019-06-12 | | Release date: | 2019-10-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural insights into the enzyme specificity of a novel omega-transaminase from the thermophilic bacterium Sphaerobacter thermophilus.
J.Struct.Biol., 208, 2019
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6J52
 | | Crystal structure of CARD-only protein in frog virus 3 | | Descriptor: | Caspase recruitment domain-only protein | | Authors: | Park, H.H, Kwon, S. | | Deposit date: | 2019-01-10 | | Release date: | 2019-02-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.504 Å) | | Cite: | Structural transformation-mediated dimerization of caspase recruitment domain revealed by the crystal structure of CARD-only protein in frog virus 3.
J. Struct. Biol., 205, 2019
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