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6BL6
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BU of 6bl6 by Molmil
Crystallization of lipid A transporter MsbA from Salmonella typhimurium
Descriptor: Lipid A export ATP-binding/permease protein MsbA
Authors:Padayatti, P.S, Stanfield, R.L, Zhang, Q, Wilson, I.A, Lee, S.C.
Deposit date:2017-11-09
Release date:2019-01-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
6BKR
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BU of 6bkr by Molmil
Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
6BKM
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BU of 6bkm by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin E190D mutant apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
6BKT
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BU of 6bkt by Molmil
Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
5ZIA
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BU of 5zia by Molmil
Crystal structure of human anti-tau antibody CBTAU-24.1 in complex with its phosphorylated tau peptide
Descriptor: Heavy chain of CBTAU-24.1 antibody, Light chain (kappa) of CBTAU-24.1 antibody, phosphorylated tau peptide
Authors:Zhang, H, Wilson, I.A.
Deposit date:2018-03-14
Release date:2018-10-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody.
Structure, 26, 2018
6BQB
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BU of 6bqb by Molmil
MGG4 Fab in complex with peptide
Descriptor: GLYCEROL, MGG4 Fab heavy chain, MGG4 Fab light chain, ...
Authors:Oyen, D, Tan, J, Lanzavecchia, A, Wilson, I.A.
Deposit date:2017-11-27
Release date:2018-03-07
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.769 Å)
Cite:A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.
Nat. Med., 24, 2018
6BZV
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BU of 6bzv by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the GL precursor of the broadly neutralizing antibody 19B3
Descriptor: 19B3 GL Heavy Chain, 19B3 GL Light Chain, E2 AS412 peptide
Authors:Tzarum, N, Aleman, F, Wilson, I.A, Law, M.
Deposit date:2017-12-26
Release date:2018-06-20
Last modified:2022-02-02
Method:X-RAY DIFFRACTION (2.654 Å)
Cite:Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BKP
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BU of 6bkp by Molmil
Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
6BKD
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BU of 6bkd by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3D
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3D heavy chain, Fab AR3D light chain, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2017-11-08
Release date:2018-12-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies.
Sci Adv, 5, 2019
6BKN
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BU of 6bkn by Molmil
Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
6BXA
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BU of 6bxa by Molmil
Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 2 (VLR2) bound
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R.
Deposit date:2017-12-18
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.
J. Mol. Biol., 430, 2018
7SBU
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BU of 7sbu by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a highly potent antibody J08 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, J08 Fab heavy chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2021-09-25
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T1V
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BU of 7t1v by Molmil
Crystal structure of an equine H7 hemagglutinin from A/equine/NY/49/73 (H7N7) in complex with 3'-GcLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2021-12-02
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:N -Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses.
J.Virol., 96, 2022
7SJS
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BU of 7sjs by Molmil
Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CC40.8
Descriptor: ACETATE ION, CC40.8 Fab heavy chain, CC40.8 Fab light chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-10-18
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.612 Å)
Cite:A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
Sci Transl Med, 14, 2022
7T7B
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BU of 7t7b by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2021-12-14
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron.
Commun Biol, 5, 2022
3KU5
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BU of 3ku5 by Molmil
Crystal structure of a H2N2 influenza virus hemagglutinin, human like
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2009-11-26
Release date:2010-01-19
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic.
J.Virol., 84, 2010
3MJ8
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BU of 3mj8 by Molmil
Crystal structure of HL4E10 Fab, a hamster Ab stimulatory for gammadelta T cells
Descriptor: STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB LIGHT CHAIN
Authors:Verdino, P, Wilson, I.A.
Deposit date:2010-04-12
Release date:2011-04-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for gammadelta T cells.
Plos One, 6, 2011
3MBE
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BU of 3mbe by Molmil
TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II H2-IAg7 ALPHA CHAIN, ...
Authors:Corper, A.L, Yoshida, K, Teyton, L, Wilson, I.A.
Deposit date:2010-03-25
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.886 Å)
Cite:The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.
J.Clin.Invest., 120, 2010
3KU6
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BU of 3ku6 by Molmil
Crystal structure of a H2N2 influenza virus hemagglutinin, 226L/228G
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2009-11-26
Release date:2010-01-19
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic.
J.Virol., 84, 2010
3MTX
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BU of 3mtx by Molmil
Crystal structure of chicken MD-1
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, GLYCEROL, Protein MD-1, ...
Authors:Yoon, S.I, Hong, M, Han, G.W, Wilson, I.A.
Deposit date:2010-05-01
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MUH
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BU of 3muh by Molmil
Crystal structure of PG9 light chain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody PG9 light chain
Authors:Pejchal, R, Walker, L.M, Burton, D.R, Wilson, I.A.
Deposit date:2010-05-03
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MUG
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BU of 3mug by Molmil
Crystal structure of human Fab PG16, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody PG16 Heavy Chain, ...
Authors:Pejchal, R, Walker, L.M, Burton, D.R, Wilson, I.A.
Deposit date:2010-05-03
Release date:2010-06-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MJ9
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BU of 3mj9 by Molmil
Crystal structure of JAML in complex with the stimulatory antibody HL4E10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Junctional adhesion molecule-like, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, ...
Authors:Verdino, P, Wilson, I.A.
Deposit date:2010-04-12
Release date:2011-02-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular insights into gamma delta T cell costimulation by an anti-JAML antibody.
Structure, 19, 2011
3LZG
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BU of 3lzg by Molmil
Crystal structure of a 2009 H1N1 influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2010-03-01
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010
3MU3
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BU of 3mu3 by Molmil
Crystal structure of chicken MD-1 complexed with lipid IVa
Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, GLYCEROL, ...
Authors:Yoon, S.I, Hong, M, Han, G.W, Wilson, I.A.
Deposit date:2010-05-01
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010

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