5ZIA

Crystal structure of human anti-tau antibody CBTAU-24.1 in complex with its phosphorylated tau peptide

Summary for 5ZIA

Entry DOI	10.2210/pdb5zia/pdb
Descriptor	Heavy chain of CBTAU-24.1 antibody, Light chain (kappa) of CBTAU-24.1 antibody, phosphorylated tau peptide, ... (4 entities in total)
Functional Keywords	antibody, tau protein, immune system
Biological source	Homo sapiens More
Total number of polymer chains	18
Total formula weight	297450.09
Authors	Zhang, H.,Wilson, I.A. (deposition date: 2018-03-14, release date: 2018-10-31, Last modification date: 2023-11-22)
Primary citation	Zhang, H.,Zhu, X.,Pascual, G.,Wadia, J.S.,Keogh, E.,Hoozemans, J.J.,Siregar, B.,Inganas, H.,Stoop, E.J.M.,Goudsmit, J.,Apetri, A.,Koudstaal, W.,Wilson, I.A. Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody. Structure, 26:1626-1634.e4, 2018 Cited by PubMed: 30318466 DOI: 10.1016/j.str.2018.08.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.603 Å)

Structure validation