7KKK
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![BU of 7kkk by Molmil](/molmil-images/mine/7kkk) | SARS-CoV-2 Spike in complex with neutralizing nanobody Nb6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium | Deposit date: | 2020-10-27 | Release date: | 2020-11-11 | Last modified: | 2021-04-21 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science, 370, 2020
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7KKL
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![BU of 7kkl by Molmil](/molmil-images/mine/7kkl) | SARS-CoV-2 Spike in complex with neutralizing nanobody mNb6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium | Deposit date: | 2020-10-27 | Release date: | 2020-11-11 | Last modified: | 2021-04-21 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science, 370, 2020
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6AAX
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![BU of 6aax by Molmil](/molmil-images/mine/6aax) | Crystal structure of TFB1M and h45 with SAM in homo sapiens | Descriptor: | DI(HYDROXYETHYL)ETHER, Dimethyladenosine transferase 1, mitochondrial, ... | Authors: | Liu, X, Shen, S, Wu, P, Li, F, Gong, Q, Wu, J, Zhang, H, Shi, Y. | Deposit date: | 2018-07-19 | Release date: | 2019-06-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.994 Å) | Cite: | Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function. Nucleic Acids Res., 47, 2019
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6AJK
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![BU of 6ajk by Molmil](/molmil-images/mine/6ajk) | Crystal structure of TFB1M and h45 in homo sapiens | Descriptor: | Dimethyladenosine transferase 1, mitochondrial, RNA (28-MER) | Authors: | Liu, X, Shen, S, Wu, P, Li, F, Wang, C, Gong, Q, Wu, J, Zhang, H, Shi, Y. | Deposit date: | 2018-08-28 | Release date: | 2019-06-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function. Nucleic Acids Res., 47, 2019
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6B7N
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![BU of 6b7n by Molmil](/molmil-images/mine/6b7n) | Cryo-electron microscopy structure of porcine delta coronavirus spike protein in the pre-fusion state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shang, J, Zheng, Y, Yang, Y, Liu, C, Geng, Q, Tai, W, Du, L, Zhou, Y, Zhang, W, Li, F. | Deposit date: | 2017-10-04 | Release date: | 2017-10-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-Electron Microscopy Structure of Porcine Deltacoronavirus Spike Protein in the Prefusion State J. Virol., 92, 2018
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6IYA
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![BU of 6iya by Molmil](/molmil-images/mine/6iya) | |
6BV4
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![BU of 6bv4 by Molmil](/molmil-images/mine/6bv4) | Crystal structure of porcine aminopeptidase-N with Methionine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.-L, Li, F. | Deposit date: | 2017-12-12 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach. Sci Rep, 7, 2017
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6BUY
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![BU of 6buy by Molmil](/molmil-images/mine/6buy) | Crystal structure of porcine aminopeptidase-N with Glycine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.-L, Li, F. | Deposit date: | 2017-12-11 | Release date: | 2018-01-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach. Sci Rep, 7, 2017
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6BV2
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![BU of 6bv2 by Molmil](/molmil-images/mine/6bv2) | Crystal structure of porcine aminopeptidase-N with Isoleucine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.-L, Li, F. | Deposit date: | 2017-12-12 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach. Sci Rep, 7, 2017
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6BV1
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![BU of 6bv1 by Molmil](/molmil-images/mine/6bv1) | Crystal structure of porcine aminopeptidase-N with Aspartic acid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.-L, Li, F. | Deposit date: | 2017-12-12 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach. Sci Rep, 7, 2017
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6BV3
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![BU of 6bv3 by Molmil](/molmil-images/mine/6bv3) | Crystal structure of porcine aminopeptidase-N with Leucine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.-L, Li, F. | Deposit date: | 2017-12-12 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach. Sci Rep, 7, 2017
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6CV0
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![BU of 6cv0 by Molmil](/molmil-images/mine/6cv0) | Cryo-electron microscopy structure of infectious bronchitis coronavirus spike protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shang, J, Zheng, Y, Yang, Y, Liu, C, Geng, Q, Luo, C, Zhang, W, Li, F. | Deposit date: | 2018-03-27 | Release date: | 2018-04-18 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Cryo-EM structure of infectious bronchitis coronavirus spike protein reveals structural and functional evolution of coronavirus spike proteins. PLoS Pathog., 14, 2018
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6BV0
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![BU of 6bv0 by Molmil](/molmil-images/mine/6bv0) | Crystal structure of porcine aminopeptidase-N with Arginine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.-L, Li, F. | Deposit date: | 2017-12-12 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach. Sci Rep, 7, 2017
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8GY6
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![BU of 8gy6 by Molmil](/molmil-images/mine/8gy6) | |
4KX8
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![BU of 4kx8 by Molmil](/molmil-images/mine/4kx8) | Crystal structure of human aminopeptidase A complexed with amastatin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KXB
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![BU of 4kxb by Molmil](/molmil-images/mine/4kxb) | Crystal structure of human aminopeptidase A complexed with bestatin | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KX7
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![BU of 4kx7 by Molmil](/molmil-images/mine/4kx7) | Crystal structure of human aminopeptidase A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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3SCL
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![BU of 3scl by Molmil](/molmil-images/mine/3scl) | Crystal structure of spike protein receptor-binding domain from SARS coronavirus epidemic strain complexed with human-civet chimeric receptor ACE2 | Descriptor: | Angiotensin-converting enzyme 2 chimera, CHLORIDE ION, Spike glycoprotein, ... | Authors: | Wu, K, Peng, G, Wilken, M, Geraghty, R, Li, F. | Deposit date: | 2011-06-07 | Release date: | 2012-02-08 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus. J.Biol.Chem., 287, 2012
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3SCJ
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![BU of 3scj by Molmil](/molmil-images/mine/3scj) | Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus civet strain complexed with human receptor ACE2 | Descriptor: | Angiotensin-converting enzyme 2, CHLORIDE ION, Spike glycoprotein, ... | Authors: | Wu, K, Peng, G, Wilken, M, Geraghty, R, Li, F. | Deposit date: | 2011-06-07 | Release date: | 2012-02-08 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus. J.Biol.Chem., 287, 2012
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5GJU
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![BU of 5gju by Molmil](/molmil-images/mine/5gju) | DEAD-box RNA helicase | Descriptor: | ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DeaD | Authors: | Xu, L, Li, F, Wang, L, Shi, Y. | Deposit date: | 2016-07-02 | Release date: | 2017-05-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions. Structure, 25, 2017
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5Y1U
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![BU of 5y1u by Molmil](/molmil-images/mine/5y1u) | Crystal structure of RBBP4 bound to AEBP2 RRK motif | Descriptor: | Histone-binding protein RBBP4, SULFATE ION, Zinc finger protein AEBP2 | Authors: | Sun, A, Li, F, Wu, J, Shi, Y. | Deposit date: | 2017-07-21 | Release date: | 2018-04-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.141 Å) | Cite: | Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4 Protein Cell, 2017
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5GMV
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![BU of 5gmv by Molmil](/molmil-images/mine/5gmv) | LC3B-FUNDC1 complex | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FUN14 domain-containing protein 1 | Authors: | Lv, M, Wang, C, Li, F. | Deposit date: | 2016-07-17 | Release date: | 2017-03-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy Protein Cell, 8, 2017
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4L3N
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![BU of 4l3n by Molmil](/molmil-images/mine/4l3n) | Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | Authors: | Chen, Y, Rajashankar, K.R, Yang, Y, Agnihothram, S.S, Liu, C, Lin, Y.-L, Baric, R.S, Li, F. | Deposit date: | 2013-06-06 | Release date: | 2013-07-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus. J.Virol., 87, 2013
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8UZE
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![BU of 8uze by Molmil](/molmil-images/mine/8uze) | Crystal structure of chimeric bat coronavirus BANAL-20-236 RBD complexed with chimeric mouse ACE2 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, W, Shi, K, Aihara, H, Li, F. | Deposit date: | 2023-11-15 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Crystal structure of chimeric RBD complexed with chimeric mouse ACE2 To Be Published
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4KXC
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![BU of 4kxc by Molmil](/molmil-images/mine/4kxc) | Crystal structure of human aminopeptidase A complexed with glutamate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-25 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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