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5ZHJ
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BU of 5zhj by Molmil
Crystal structure of TrmD from Mycobacterium tuberculosis in complex with S-adenosyl homocysteine (SAH)
Descriptor: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase
Authors:Zhong, W, Pasunooti, K.K, Balamkundu, S, Wong, Y.W, Nah, Q, Liu, C.F, Lescar, J, Dedon, P.C.
Deposit date:2018-03-13
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
J.Med.Chem., 62, 2019
5ZBI
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BU of 5zbi by Molmil
Crystal structure of asparaginyl endopeptidases from Viola Canadensis
Descriptor: Peptide asparaginyl ligase, SODIUM ION
Authors:Wong, Y.H, Lescar, J.
Deposit date:2018-02-12
Release date:2018-05-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal structure of Peptide asparaginyl ligase from Viola canadensis
To Be Published
2J7W
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BU of 2j7w by Molmil
Dengue virus NS5 RNA dependent RNA polymerase domain complexed with 3' dGTP
Descriptor: DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-TRIPHOSPHATE, POLYPROTEIN, ...
Authors:Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
2J7U
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BU of 2j7u by Molmil
Dengue virus NS5 RNA dependent RNA polymerase domain
Descriptor: CHLORIDE ION, MAGNESIUM ION, RNA DEPENDENT RNA POLYMERASE, ...
Authors:Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
7DU3
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BU of 7du3 by Molmil
ThiL in complex with AMP-PNP
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Lin, J.Q, Lescar, J.
Deposit date:2021-01-07
Release date:2022-03-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:ThiL in complex with AMP-PNP
To Be Published
7F8C
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BU of 7f8c by Molmil
Crystal structure of rRNA methyltransferase Erm38 in complex with sinefungin
Descriptor: Erm(38), SINEFUNGIN, SUCCINIC ACID
Authors:Goh, B.C, Lescar, J.
Deposit date:2021-07-01
Release date:2022-01-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site.
J.Biol.Chem., 298, 2022
7F8A
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BU of 7f8a by Molmil
Crystal structure of rRNA methyltransferase Erm38
Descriptor: Erm(38)
Authors:Goh, B.C, Lescar, J.
Deposit date:2021-07-01
Release date:2022-01-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site.
J.Biol.Chem., 298, 2022
7F8B
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BU of 7f8b by Molmil
Crystal structure of rRNA methyltransferase Erm38 in complex with SAM
Descriptor: Erm(38), S-ADENOSYLMETHIONINE, SUCCINIC ACID
Authors:Goh, B.C, Lescar, J.
Deposit date:2021-07-01
Release date:2022-01-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site.
J.Biol.Chem., 298, 2022
7F5P
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BU of 7f5p by Molmil
The crystal structure of VyPAL2-C214A, a dead mutant of VyPAL2 peptide asparaginyl ligase in form I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Peptide Asparaginyl Ligases, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hu, S, Sahili, A, Lescar, J.
Deposit date:2021-06-22
Release date:2022-06-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for proenzyme maturation, substrate recognition, and ligation by a hyperactive peptide asparaginyl ligase.
Plant Cell, 34, 2022
7F5Q
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BU of 7f5q by Molmil
The crystal structure of VyPAL2 peptide asparaginyl ligase in its active enzyme form
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hu, S, Sahili, A, Lescar, J.
Deposit date:2021-06-22
Release date:2022-06-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for proenzyme maturation, substrate recognition, and ligation by a hyperactive peptide asparaginyl ligase.
Plant Cell, 34, 2022
7F5J
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BU of 7f5j by Molmil
The crystal structure of VyPAL2-I244V, a more efficient mutant of VyPAL2 peptide asparaginyl ligase in its active enzyme form
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hu, S, Sahili, A, Lescar, J.
Deposit date:2021-06-22
Release date:2022-06-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.593 Å)
Cite:Structural basis for proenzyme maturation, substrate recognition, and ligation by a hyperactive peptide asparaginyl ligase.
Plant Cell, 34, 2022
7FA0
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BU of 7fa0 by Molmil
The crystal structure of VyPAL2-C214A, a dead mutant of VyPAL2 peptide asparaginyl ligase in form II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Peptide Asparaginyl Ligases, ...
Authors:Hu, S, Sahili, A, Lescar, J.
Deposit date:2021-07-05
Release date:2022-07-13
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for proenzyme maturation, substrate recognition, and ligation by a hyperactive peptide asparaginyl ligase.
Plant Cell, 34, 2022
5FC8
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BU of 5fc8 by Molmil
Mouse importin alpha: Dengue 3 NS5 C-terminal NLS peptide complex
Descriptor: Importin subunit alpha-1, Nonstructural protein 5
Authors:Smith, K.M, Forwood, J.K.
Deposit date:2015-12-15
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.
PLoS Pathog., 12, 2016
5K5M
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BU of 5k5m by Molmil
Co-Crystal Structure of Dengue Virus Serotype 2 RNA Dependent RNA Polymerase with Compound 27
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-[(3-methoxyphenyl)sulfonyl]benzamide, RNA Dependent RNA Polymerase, ...
Authors:Arora, R, Benson, T.E.
Deposit date:2016-05-23
Release date:2016-08-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
Plos Pathog., 12, 2016
7BWE
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BU of 7bwe by Molmil
Consensus Chitin binding domain
Descriptor: Chitin binding beak protein 3
Authors:Mohanram, H, Miserez, A.
Deposit date:2020-04-14
Release date:2021-04-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of a consensus chitin-binding domain revealed by solution NMR.
J.Struct.Biol., 213, 2021
4B3V
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BU of 4b3v by Molmil
Crystal structure of the Rubella virus glycoprotein E1 in its post-fusion form crystallized in presence of 20mM of Calcium Acetate
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Vaney, M.C, DuBois, R.M, Tortorici, M.A, Rey, F.A.
Deposit date:2012-07-26
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
1URZ
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BU of 1urz by Molmil
Low pH induced, membrane fusion conformation of the envelope protein of tick-borne encephalitis virus
Descriptor: ENVELOPE PROTEIN
Authors:Bressanelli, S, Rey, F.A.
Deposit date:2003-11-16
Release date:2004-01-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a Flavivirus Envelope Glycoprotein in its Low-Ph-Induced Membrane Fusion Conformation.
Embo J., 23, 2004
4ADG
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BU of 4adg by Molmil
Crystal structure of the Rubella virus envelope Glycoprotein E1 in post-fusion form (crystal form II)
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:DuBois, R.M, Vaney, M.C, Tortorici, M.A, Al Kurdi, R, Barba-Spaeth, G, Rey, F.A.
Deposit date:2011-12-26
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
4ADI
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BU of 4adi by Molmil
Crystal structure of the Rubella virus envelope glycoprotein E1 in post-fusion form (crystal form I)
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:DuBois, R.M, Vaney, M.C, Tortorici, M.A, Al Kurdi, R, Barba-Spaeth, G, Rey, F.A.
Deposit date:2011-12-26
Release date:2013-01-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
4ADJ
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BU of 4adj by Molmil
Crystal structure of the Rubella virus glycoprotein E1 in its post-fusion form crystallized in presence of 1mM of calcium acetate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
Authors:DuBois, R.M, Vaney, M.C, Tortorici, M.A, Al Kurdi, R, Barba-Spaeth, G, Rey, F.A.
Deposit date:2011-12-26
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
4ITZ
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BU of 4itz by Molmil
Crystal structure of the FK506 binding domain of Plasmodium vivax FKBP35 in complex with a tetrapeptide substrate
Descriptor: 70 kDa peptidylprolyl isomerase, SULFATE ION, substrate peptide
Authors:Sreekanth, R, Yoon, H.S.
Deposit date:2013-01-19
Release date:2013-03-20
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax.
Eukaryot Cell, 12, 2013
2MAU
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BU of 2mau by Molmil
Solution structure of alpha-amylase inhibitor wrightide R1 (wR1) peptide from Wrightia religiosa
Descriptor: Wrightide R1
Authors:Wang, S, Nguyen, Q, Tam, J.
Deposit date:2013-07-17
Release date:2014-07-23
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Discovery and characterization of pseudocyclic cystine-knot alpha-amylase inhibitors with high resistance to heat and proteolytic degradation.
Febs J., 281, 2014
5E6X
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BU of 5e6x by Molmil
Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
Authors:Springer, T.A, Sen, M.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
5E6W
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BU of 5e6w by Molmil
Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
Authors:Springer, T.A, Sen, M.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
5E6V
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BU of 5e6v by Molmil
Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
Authors:Sen, M, Springer, T.A.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016

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