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7F71
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BU of 7f71 by Molmil
Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) with peptidoglycan sugar moiety and glutamate
Descriptor: GLUTAMIC ACID, GLYCEROL, L,D-transpeptidase 2, ...
Authors:Kumar, P, Lamichhane, G.
Deposit date:2021-06-26
Release date:2022-05-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Allosteric cooperation in beta-lactam binding to a non-classical transpeptidase.
Elife, 11, 2022
8DFL
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BU of 8dfl by Molmil
Structure of human Kv1.3 with A0194009G09 nanobodies (alternate conformation)
Descriptor: Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2022-06-22
Release date:2022-07-13
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
8EX1
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BU of 8ex1 by Molmil
Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with Reversine
Descriptor: GLYCEROL, N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine, Tyrosine-protein kinase JAK2
Authors:Sampathkumar, P, Hubbard, S.R.
Deposit date:2022-10-24
Release date:2023-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain.
Pharmaceuticals, 16, 2023
8EX0
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BU of 8ex0 by Molmil
Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with CDK2-IV
Descriptor: 4-{[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino}-N,N-diethylbenzamide, Tyrosine-protein kinase JAK2
Authors:Sampathkumar, P, Hubbard, S.R.
Deposit date:2022-10-24
Release date:2023-02-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain.
Pharmaceuticals, 16, 2023
8EX2
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BU of 8ex2 by Molmil
Crystal structure of JAK2 JH2 (pseudokinase domain) in complex with HTSA3
Descriptor: 3,5-diphenyl-2-(trifluoromethyl)-6~{H}-pyrazolo[1,5-a]pyrimidin-7-one, GLYCEROL, Tyrosine-protein kinase JAK2
Authors:Sampathkumar, P, Hubbard, S.R.
Deposit date:2022-10-24
Release date:2023-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain.
Pharmaceuticals, 16, 2023
7SSX
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BU of 7ssx by Molmil
Structure of human Kv1.3
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
7SSZ
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BU of 7ssz by Molmil
Structure of human Kv1.3 with A0194009G09 nanobodies
Descriptor: Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
7SSY
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BU of 7ssy by Molmil
Structure of human Kv1.3 (alternate conformation)
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
7SSV
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BU of 7ssv by Molmil
Structure of human Kv1.3 with Fab-ShK fusion
Descriptor: Fab-ShK fusion, heavy chain, light chain, ...
Authors:Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R.
Deposit date:2021-11-11
Release date:2022-06-29
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
7LVT
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BU of 7lvt by Molmil
Structure of full-length GluK1 with L-Glu
Descriptor: Isoform Glur5-2 of Glutamate receptor ionotropic, kainate 1
Authors:Meyerson, J.R, Selvakumar, P.
Deposit date:2021-02-26
Release date:2021-11-03
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural and compositional diversity in the kainate receptor family.
Cell Rep, 37, 2021
4HB9
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BU of 4hb9 by Molmil
Crystal structure of a putative FAD containing monooxygenase from Photorhabdus luminescens subsp. laumondii TTO1 (Target PSI-012791)
Descriptor: 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, Similarities with probable monooxygenase
Authors:Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-09-27
Release date:2012-10-17
Last modified:2022-06-15
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Stilbene epoxidation and detoxification in a Photorhabdus luminescens -nematode symbiosis.
J.Biol.Chem., 292, 2017
4UMD
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BU of 4umd by Molmil
Crystal structure of 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase from Moraxella catarrhalis in complex with citrate
Descriptor: 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE PHOSPHATASE KDSC, CITRIC ACID
Authors:Dhindwal, S, Tomar, S, Kumar, P.
Deposit date:2014-05-16
Release date:2015-02-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Ligand-Bound Structures of 3-Deoxy-D-Manno-Octulosonate 8-Phosphate Phosphatase from Moraxella Catarrhalis Reveal a Water Channel Connecting to the Active Site for the Second Step of Catalysis
Acta Crystallogr.,Sect.D, 71, 2015
4UM7
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BU of 4um7 by Molmil
Crystal structure of 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (kdsC) from Moraxella catarrhalis in complex with Magnesium ion
Descriptor: 1,2-ETHANEDIOL, 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE PHOSPHATASE KDSC, MAGNESIUM ION
Authors:Dhindwal, S, Tomar, S, Kumar, P.
Deposit date:2014-05-15
Release date:2015-02-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Ligand-Bound Structures of 3-Deoxy-D-Manno-Octulosonate 8-Phosphate Phosphatase from Moraxella Catarrhalis Reveal a Water Channel Connecting to the Active Site for the Second Step of Catalysis
Acta Crystallogr.,Sect.D, 71, 2015
5XLW
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BU of 5xlw by Molmil
Mycobacterium tuberculosis Pantothenate kinase mutant F247A/F254A
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ...
Authors:Paul, A, Kumar, P, Surolia, A, Vijayan, M.
Deposit date:2017-05-11
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase
Acta Crystallogr F Struct Biol Commun, 73, 2017
5XMB
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BU of 5xmb by Molmil
Mycobacterium tuberculosis Pantothenate kinase mutant F247A
Descriptor: Pantothenate kinase, SULFATE ION
Authors:Paul, A, Kumar, P, Surolia, A, Vijayan, M.
Deposit date:2017-05-13
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase
Acta Crystallogr F Struct Biol Commun, 73, 2017
4CL2
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BU of 4cl2 by Molmil
structure of periplasmic metal binding protein from candidatus liberibacter asiaticus
Descriptor: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ...
Authors:Sharma, N, Selvakumar, P, Bhose, S, Ghosh, D.K, Kumar, P, Sharma, A.K.
Deposit date:2014-01-11
Release date:2015-01-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal Structure of a Periplasmic Solute Binding Protein in Metal-Free, Intermediate and Metal-Bound States from Candidatus Liberibacter Asiaticus.
J.Struct.Biol., 189, 2015
5FTW
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BU of 5ftw by Molmil
Crystal structure of glutamate O-methyltransferase in complex with S- adenosyl-L-homocysteine (SAH) from Bacillus subtilis
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHEMOTAXIS PROTEIN METHYLTRANSFERASE, GLYCEROL, ...
Authors:Sharma, R, Dhindwal, S, Batra, M, Aggarwal, M, Kumar, P, Tomar, S.
Deposit date:2016-01-18
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Pentapeptide-Independent Chemotaxis Receptor Methyltransferase (Cher) Reveals Idiosyncratic Structural Determinants for Receptor Recognition.
J.Struct.Biol., 196, 2016
4Y0U
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BU of 4y0u by Molmil
Crystal Structure of 6Alpha-Hydroxymethylpenicillanate Complexed with OXA-58, a Carbapenem hydrolyzing Class D betalactamase from Acinetobacter baumanii.
Descriptor: 2-(1-CARBOXY-2-HYDROXY-ETHYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, Beta-lactamase
Authors:Pratap, S, Katiki, M, Gill, P, Golemi-Kotra, D, Kumar, P.
Deposit date:2015-02-06
Release date:2016-01-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Active-Site Plasticity Is Essential to Carbapenem Hydrolysis by OXA-58 Class D beta-Lactamase of Acinetobacter baumannii.
Antimicrob.Agents Chemother., 60, 2015
4Y0O
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BU of 4y0o by Molmil
Crystal structure of OXA-58, a carbapenem hydrolyzing Class D beta-lactamase from Acinetobacter baumanii.
Descriptor: Beta-lactamase
Authors:Pratap, S, Katiki, M, Gill, P, Golemi-Kotra, D, Kumar, P.
Deposit date:2015-02-06
Release date:2016-01-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Active-Site Plasticity Is Essential to Carbapenem Hydrolysis by OXA-58 Class D beta-Lactamase of Acinetobacter baumannii.
Antimicrob.Agents Chemother., 60, 2015
4XTM
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BU of 4xtm by Molmil
Crystal structure of a recombinant Vatairea macrocarpa seed lectin complexed with GalNAc
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, CITRIC ACID, ...
Authors:Sousa, B.L, Silva-Filho, J.C, Kumar, P, Lyskowski, A, Bezerra, G.A, Delatorre, P, Rocha, B.A.M, Cunha, R.M.S, Nagano, C.S, Gruber, K, Cavada, B.S.
Deposit date:2015-01-23
Release date:2016-01-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a recombinant Vatairea macrocarpa seed lectin
Int.J.Biochem.Cell Biol., 2016
4XTP
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BU of 4xtp by Molmil
Crystal structure of a recombinant Vatairea macrocarpa seed lectin complexed with Tn antigen
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, CITRIC ACID, ...
Authors:Sousa, B.L, Silva-Filho, J.C, Kumar, P, Lyskowski, A, Bezerra, G.A, Delatorre, P, Rocha, B.A.M, Cunha, R.M.S, Nagano, C.S, Gruber, K, Cavada, B.S.
Deposit date:2015-01-23
Release date:2016-01-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of a recombinant Vatairea macrocarpa seed lectin
Int.J.Biochem.Cell Biol., 2016
4XXA
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BU of 4xxa by Molmil
Crystal structure of a recombinant Vatairea macrocarpa seed lectin
Descriptor: CALCIUM ION, GLYCEROL, MANGANESE (II) ION, ...
Authors:Sousa, B.L, Silva-Filho, J.C, Kumar, P, Lyskowski, A, Bezerra, G.A, Delatorre, P, Rocha, B.A.M, Cunha, R.M.S, Nagano, C.S, Gruber, K, Cavada, B.S.
Deposit date:2015-01-30
Release date:2016-01-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a recombinant Vatairea macrocarpa seed lectin
Int.J.Biochem.Cell Biol., 2016
4WV8
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BU of 4wv8 by Molmil
Crystal structure of a recombinant Vatairea macrocarpa seed lectin complexed with lactose
Descriptor: CALCIUM ION, MANGANESE (II) ION, Seed lectin, ...
Authors:Sousa, B.L, Silva-Filho, J.C, Kumar, P, Lyskowski, A, Bezerra, G.A, Delatorre, P, Rocha, B.A.M, Cunha, R.M.S, Nagano, C.S, Gruber, K, Cavada, B.S.
Deposit date:2014-11-04
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural characterization of a Vatairea macrocarpa lectin in complex with a tumor-associated antigen: A new tool for cancer research.
Int.J.Biochem.Cell Biol., 72, 2016
4Y0T
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BU of 4y0t by Molmil
Crystal structure of apo form of OXA-58, a Carbapenem hydrolyzing Class D beta-lactamase from Acinetobacter baumanii (P21, 4mol/ASU)
Descriptor: Beta-lactamase
Authors:Pratap, S, Katiki, M, Gill, P, Golemi-Kotra, D, Kumar, P.
Deposit date:2015-02-06
Release date:2016-01-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Active-Site Plasticity Is Essential to Carbapenem Hydrolysis by OXA-58 Class D beta-Lactamase of Acinetobacter baumannii.
Antimicrob.Agents Chemother., 60, 2015
7W61
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BU of 7w61 by Molmil
Crystal structure of farnesol dehydrogenase from Helicoverpa armigera
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Farnesol dehydrogenase, ...
Authors:Kumar, R, Das, J, Mahto, J.K, Sharma, M, Kumar, P, Sharma, A.K.
Deposit date:2021-12-01
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure and molecular characterization of NADP + -farnesol dehydrogenase from cotton bollworm, Helicoverpaarmigera.
Insect Biochem.Mol.Biol., 147, 2022

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