5XMB

Mycobacterium tuberculosis Pantothenate kinase mutant F247A

Summary for 5XMB

Entry DOI	10.2210/pdb5xmb/pdb
Descriptor	Pantothenate kinase, SULFATE ION (3 entities in total)
Functional Keywords	homodimer, coa biosynthesis, nucleotide binding, concerted movement, structural transformation, transferase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	4
Total formula weight	142899.27
Authors	Paul, A.,Kumar, P.,Surolia, A.,Vijayan, M. (deposition date: 2017-05-13, release date: 2018-05-16, Last modification date: 2023-11-22)
Primary citation	Paul, A.,Kumar, P.,Surolia, A.,Vijayan, M. Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase Acta Crystallogr F Struct Biol Commun, 73:635-643, 2017 Cited by PubMed: 29095158 DOI: 10.1107/S2053230X17015667 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation