6A6O
| Crystal structure of acetyl ester-xyloside bifunctional hydrolase from Caldicellulosiruptor lactoaceticus | Descriptor: | Esterase/lipase-like protein | Authors: | Cao, H, Huang, Y, Sun, L.C, Liu, X, Liu, T.F, Wang, F.Z, Xin, F.J. | Deposit date: | 2018-06-28 | Release date: | 2019-06-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Insights into the Dual-Substrate Recognition and Catalytic Mechanisms of a Bifunctional Acetyl Ester-Xyloside Hydrolase from Caldicellulosiruptor lactoaceticus. Acs Catalysis, 9, 2019
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6AIN
| Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PnpA | Authors: | Chen, Q.Z, Huang, Y, Duan, Y.J, Li, Z.K, Liu, W.D, Cui, Z.L. | Deposit date: | 2018-08-24 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4: The key enzyme involved in p-nitrophenol degradation. Biochem. Biophys. Res. Commun., 504, 2018
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1MIT
| RECOMBINANT CUCURBITA MAXIMA TRYPSIN INHIBITOR V (RCMTI-V) (NMR, MINIMIZED AVERAGE STRUCTURE) | Descriptor: | TRYPSIN INHIBITOR V | Authors: | Cai, M, Gong, Y, Huang, Y, Liu, J, Prakash, O, Wen, L, Wen, J.J, Huang, J.-K, Krishnamoorthi, R. | Deposit date: | 1995-10-26 | Release date: | 1996-04-03 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure and backbone dynamics of recombinant Cucurbita maxima trypsin inhibitor-V determined by NMR spectroscopy. Biochemistry, 35, 1996
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1OX1
| crystal structure of the bovine trypsin complex with a synthetic 11 peptide inhibitor | Descriptor: | 11-mer peptide, CALCIUM ION, Trypsinogen, ... | Authors: | Wu, G, Huang, Y, Zhu, G, Huang, Q, Tang, Y, Miyake, H, Kusunoki, M. | Deposit date: | 2003-03-31 | Release date: | 2004-05-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | crystal structure of the bovine trypsin complex with a synthetic 11 peptide inhibitor To be published
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4ZS3
| Structural complex of 5-aminofluorescein bound to the FTO protein | Descriptor: | 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | Authors: | Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. | Deposit date: | 2015-05-13 | Release date: | 2015-11-04 | Last modified: | 2015-11-18 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137, 2015
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4ZS2
| Structural complex of FTO/fluorescein | Descriptor: | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | Authors: | Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. | Deposit date: | 2015-05-13 | Release date: | 2015-11-04 | Last modified: | 2015-11-18 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137, 2015
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4MZ4
| Discovery of an Irreversible HCV NS5B Polymerase Inhibitor | Descriptor: | 1-[(2-chloroquinolin-3-yl)methyl]-6-fluoro-5-methyl-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxylic acid, PHOSPHATE ION, RNA-directed RNA polymerase | Authors: | Zeng, Q, Anilkumar, G.N, Rosenblum, S.B, Huang, H.-C, Lesburg, C.A, Jiang, Y, Selyutin, O, Chan, T.-Y, Bennett, F, Chen, K.X, Venkatraman, S, Sannigrahi, M, Velazquez, F, Duca, J.S, Gavalas, S, Huang, Y, Pu, H, Wang, L, Pinto, P, Vibulbhan, B, Agrawal, S, Ferrari, E, Jiang, C.-K, Li, C, Hesk, D, Gesell, J, Sorota, S, Shih, N.-Y, Njoroge, F.G, Kozlowski, J.A. | Deposit date: | 2013-09-29 | Release date: | 2013-12-11 | Last modified: | 2013-12-18 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Discovery of an irreversible HCV NS5B polymerase inhibitor. Bioorg.Med.Chem.Lett., 23, 2013
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3KCV
| Structure of formate channel | Descriptor: | Probable formate transporter 1 | Authors: | Wang, Y, Huang, Y, Wang, J, Yan, N, Shi, Y. | Deposit date: | 2009-10-22 | Release date: | 2009-12-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.198 Å) | Cite: | Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel Nature, 462, 2009
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3KCU
| Structure of formate channel | Descriptor: | 2-(6-(2-CYCLOHEXYLETHOXY)-TETRAHYDRO-4,5-DIHYDROXY-2(HYDROXYMETHYL)-2H-PYRAN-3-YLOXY)-TETRAHYDRO-6(HYDROXYMETHYL)-2H-PY RAN-3,4,5-TRIOL, Probable formate transporter 1 | Authors: | Wang, Y, Huang, Y, Wang, J, Yan, N, Shi, Y. | Deposit date: | 2009-10-22 | Release date: | 2009-12-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.243 Å) | Cite: | Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel Nature, 462, 2009
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8HDG
| Small peptide enhances the binding of nutline-3a to MdmX | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Uncharacterized protein DKFZp686B01123 | Authors: | Cheng, X.Y, Huang, Y, Wei, Q.Y, Huang, J.J, Peng, Y.W, Su, Z.D. | Deposit date: | 2022-11-04 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Small peptide enhances the binding of nutline-3a to MdmX To Be Published
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3U4R
| Novel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamides | Descriptor: | 1-[(2-aminopyridin-4-yl)methyl]-5-chloro-N-({3-[(methylsulfonyl)amino]phenyl}sulfonyl)-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxamide, RNA-directed RNA polymerase | Authors: | Anilkumar, G.N, Selyutin, O, Rosenblum, S.B, Zeng, Q, Jiang, Y, Chan, T.-Y, Pu, H, Wang, L, Bennett, F, Chen, K.X, Lesburg, C.A, Duca, J.S, Gavalas, S, Huang, Y, Pinto, P, Sannagrahi, M, Velazquez, F, Venkataraman, S, Vilbubhan, B, Agrawal, S, Ferrari, E, Jiang, C.-K, Huang, H.-C, Shih, N.-Y, Njoroge, F.G, Kozlowski, J.A. | Deposit date: | 2011-10-10 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides. Bioorg.Med.Chem.Lett., 22, 2012
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3U4O
| Novel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamides | Descriptor: | 1-[(2-aminopyridin-4-yl)methyl]-5-chloro-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxylic acid, PHOSPHATE ION, RNA-directed RNA polymerase | Authors: | Anilkumar, G.N, Selyutin, O, Rosenblum, S.B, Zeng, Q, Jiang, Y, Chan, T.-Y, Pu, H, Wang, L, Bennett, F, Chen, K.X, Lesburg, C.A, Duca, J.S, Gavalas, S, Huang, Y, Pinto, P, Sannigrahi, M, Velazquez, F, Venkataraman, S, Vilbubhan, B, Agrawal, S, Ferrari, E, Jiang, C.-K, Huang, H.-C, Shih, N.-Y, Njoroge, F.G, Kozlowski, J.A. | Deposit date: | 2011-10-10 | Release date: | 2011-12-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides. Bioorg.Med.Chem.Lett., 22, 2012
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8YTJ
| Cryo-EM structure of enterovirus A71 mature virion | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2024-03-26 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2 To Be Published
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8YTB
| Cryo-EM structure of enterovirus A71 empty particle | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2024-03-25 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Cryo-EM structure of enterovirus A71 empty particle To Be Published
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8X98
| Cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab h1A6.2 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab h1A6.2 To Be Published
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8X99
| Cryo-EM structure of coxsackievirus A16 A-particle in complex with Fab h1A6.2 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Cryo-EM structure of coxsackievirus A16 A-particle in complex with Fab h1A6.2 To Be Published
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8X95
| Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2 To Be Published
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8X9A
| Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 To Be Published
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8X96
| Cryo-EM structure of enterovirus A71 A-particle in complex with Fab h1A6.2 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Cryo-EM structure of enterovirus A71 A-particle in complex with Fab h1A6.2 To Be Published
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8X9B
| Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement) | Descriptor: | Capsid protein VP1, Genome polyprotein, The heavy chain of Fab h1A6.2, ... | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement) To Be Published
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8X97
| Cryo-EM structure of enterovirus A71 empty particle in complex with Fab h1A6.2 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Cryo-EM structure of enterovirus A71 empty particle in complex with Fab h1A6.2 To Be Published
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1MV4
| TM9A251-284: A Peptide Model of the C-Terminus of a Rat Striated Alpha Tropomyosin | Descriptor: | Tropomyosin 1 alpha chain | Authors: | Greenfield, N.J, Swapna, G.V.T, Huang, Y, Palm, T, Graboski, S, Montelione, G.T, Hitchcock-Degregori, S.E. | Deposit date: | 2002-09-24 | Release date: | 2003-02-18 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | The Structure of the Carboxyl Terminus of Striated alpha-Tropomyosin in Solution Reveals an Unusual Parallel Arrangement of Interacting alpha-Helices Biochemistry, 42, 2003
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4Y25
| Bacterial polysaccharide outer membrane secretin | Descriptor: | Poly-beta-1,6-N-acetyl-D-glucosamine export protein | Authors: | Wang, Y, AndolePannuri, A, Ni, D, Zhou, H, Cao, X, Lu, X, Romeo, T, Huang, Y. | Deposit date: | 2015-02-09 | Release date: | 2016-03-16 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.821 Å) | Cite: | Structural Basis for Translocation of a Biofilm-supporting Exopolysaccharide across the Bacterial Outer Membrane J.Biol.Chem., 291, 2016
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1ZGL
| Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, Myelin basic protein, ... | Authors: | Li, Y, Huang, Y, Lue, J, Quandt, J.A, Martin, R, Mariuzza, R.A. | Deposit date: | 2005-04-21 | Release date: | 2005-10-18 | Last modified: | 2020-02-19 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule. Embo J., 24, 2005
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6KCO
| Shuguo PWWP in complex with ssDNA | Descriptor: | DNA (5'-D(*TP*CP*CP*CP*T)-3'), LD23804p | Authors: | Liu, Y.C, Huang, Y. | Deposit date: | 2019-06-28 | Release date: | 2020-07-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Shuguo PWWP in complex with ssDNA To Be Published
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