8J64
 
 | | Crystal structure of Toxoplasma gondii MIC2-M2AP complex | | Descriptor: | MIC2-associated protein, Micronemal protein MIC2 | | Authors: | Zhang, S, Wang, F.F, Zhang, D.J, Song, G.J, Springer, T.A. | | Deposit date: | 2023-04-24 | | Release date: | 2023-08-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural insights into MIC2 recognition by MIC2-associated protein in Toxoplasma gondii.
Commun Biol, 6, 2023
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5ZXV
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3L6P
 | | Crystal Structure of Dengue Virus 1 NS2B/NS3 protease | | Descriptor: | CADMIUM ION, NICKEL (II) ION, SULFATE ION, ... | | Authors: | Chandramouli, S, Joseph, J.S, Daudenarde, S, Gatchalian, J, Cornillez-Ty, C, Kuhn, P. | | Deposit date: | 2009-12-23 | | Release date: | 2010-03-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Serotype-specific structural differences in the protease-cofactor complexes of the dengue virus family.
J.Virol., 84, 2010
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5YY5
 | | Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, Light chain, ... | | Authors: | Zhang, S, Wang, P, Zhou, P, Wang, X, Zhang, L. | | Deposit date: | 2017-12-08 | | Release date: | 2018-08-01 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
Cell Rep, 24, 2018
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7D10
 | | Human NKCC1 | | Descriptor: | PALMITIC ACID, Solute carrier family 12 member 2 | | Authors: | Zhang, S, Yang, M. | | Deposit date: | 2020-09-12 | | Release date: | 2021-04-14 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2.
Commun Biol, 4, 2021
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7D14
 | | Mouse KCC2 | | Descriptor: | Solute carrier family 12 member 5 | | Authors: | Zhang, S, Yang, M. | | Deposit date: | 2020-09-13 | | Release date: | 2021-04-14 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2.
Commun Biol, 4, 2021
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3LKW
 | | Crystal Structure of Dengue Virus 1 NS2B/NS3 protease active site mutant | | Descriptor: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Chandramouli, S, Joseph, J.S, Daudenarde, S, Gatchalian, J, Cornillez-Ty, C, Kuhn, P. | | Deposit date: | 2010-01-28 | | Release date: | 2010-03-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Serotype-specific structural differences in the protease-cofactor complexes of the dengue virus family.
J.Virol., 84, 2010
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3RL1
 | | HIV RT derived peptide complexed to HLA-A*0301 | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-3 alpha chain, ... | | Authors: | Zhang, S, Liu, J, Cheng, H, Tan, S, Qi, J, Yan, J, Gao, G.F. | | Deposit date: | 2011-04-19 | | Release date: | 2012-02-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
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3RL2
 | | HIV Nef derived peptide Nef73 complexed to HLA-A*0301 | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-3 alpha chain, ... | | Authors: | Zhang, S, Liu, J, Cheng, H, Tan, S, Qi, J, Yan, J, Gao, G.F. | | Deposit date: | 2011-04-19 | | Release date: | 2012-02-29 | | Method: | X-RAY DIFFRACTION (2.386 Å) | | Cite: | Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
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1F31
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3H6P
 | | Crystal structure of Rv3019c-Rv3020c from Mycobacterium tuberculosis | | Descriptor: | ESAT-6 LIKE PROTEIN ESXS, ESAT-6-like protein esxR, GLYCEROL | | Authors: | Chan, S, Arbing, M, Phan, T, Kaufmann, M, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2009-04-23 | | Release date: | 2009-06-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Crystal structure of Rv3019c-Rv3020c from Mycobacterium tuberculosis
To be Published
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6H42
 | | crystal structure of the human TGT catalytic subunit QTRT1 | | Descriptor: | BROMIDE ION, CHLORIDE ION, GLUTAMIC ACID, ... | | Authors: | Johannsson, S, Neumann, P, Ficner, R. | | Deposit date: | 2018-07-20 | | Release date: | 2018-09-05 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.
Biomolecules, 8, 2018
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8JTZ
 | | hOCT1 in complex with spironolactone in outward facing partially occluded conformation | | Descriptor: | SPIRONOLACTONE, Solute carrier family 22 member 1 | | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | | Deposit date: | 2023-06-22 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
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8JTX
 | | hOCT1 in complex with nb5660 in inward facing fully open conformation | | Descriptor: | Solute carrier family 22 member 1, nanobody 56 | | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | | Deposit date: | 2023-06-22 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
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8JU0
 | | hOCT1 in complex with spironolactone in inward facing occluded conformation | | Descriptor: | SPIRONOLACTONE, Solute carrier family 22 member 1 | | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | | Deposit date: | 2023-06-23 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
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8JTT
 | | hOCT1 in complex with metformin in outward occluded conformation | | Descriptor: | Metformin, Solute carrier family 22 member 1 | | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | | Deposit date: | 2023-06-22 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.87 Å) | | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
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8JTW
 | | hOCT1 in complex with nb5660 in inward facing partially open 1 conformation | | Descriptor: | Solute carrier family 22 member 1, nanobody 56 | | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | | Deposit date: | 2023-06-22 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
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8JTY
 | | hOCT1 in complex with nb5660 in inward facing partially open 2 conformation | | Descriptor: | Solute carrier family 22 member 1, nanobody 56 | | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | | Deposit date: | 2023-06-22 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
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8JTS
 | | hOCT1 in complex with metformin in outward open conformation | | Descriptor: | Metformin, Solute carrier family 22 member 1 | | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | | Deposit date: | 2023-06-22 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.14 Å) | | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
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8JTV
 | | hOCT1 in complex with metformin in inward occluded conformation | | Descriptor: | Metformin, Solute carrier family 22 member 1 | | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | | Deposit date: | 2023-06-22 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.77 Å) | | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
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6H45
 | | crystal structure of the human TGT catalytic subunit QTRT1 in complex with queuine | | Descriptor: | 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, BROMIDE ION, CHLORIDE ION, ... | | Authors: | Johannsson, S, Neumann, P, Ficner, R. | | Deposit date: | 2018-07-20 | | Release date: | 2018-09-05 | | Last modified: | 2023-03-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.
Biomolecules, 8, 2018
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8K70
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7N6W
 | | Structure of uncleaved HIV-1 JR-FL Env glycoprotein trimer in state U2 bound to small Molecule HIV-1 Entry Inhibitor BMS-378806 | | Descriptor: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Zhang, S, Wang, K, Mao, Y. | | Deposit date: | 2021-06-09 | | Release date: | 2021-09-22 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer.
J.Virol., 95, 2021
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7N6U
 | | Structure of uncleaved HIV-1 JR-FL Env glycoprotein trimer in state U1 bound to small Molecule HIV-1 Entry Inhibitor BMS-378806 | | Descriptor: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Zhang, S, Wang, K, Mao, Y. | | Deposit date: | 2021-06-09 | | Release date: | 2021-09-22 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer.
J.Virol., 95, 2021
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3UGL
 | | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta | | Descriptor: | PHOSPHATE ION, Proteine kinase C delta type, ZINC ION, ... | | Authors: | Shanmugasundararaj, S, Stehle, T, Miller, K.W. | | Deposit date: | 2011-11-02 | | Release date: | 2012-12-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.357 Å) | | Cite: | Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
Biophys.J., 103, 2012
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