8IK2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ik2 by Molmil](/molmil-images/mine/8ik2) | RhlA exhibits dual thioesterase and acyltransferase activities during rhamnolipid biosynthesis | Descriptor: | (3~{S})-3-oxidanyldecanoic acid, 3-(3-hydroxydecanoyloxy)decanoate synthase | Authors: | Tang, T, Fu, L.H, Xie, W.H, Luo, Y.Z, Zhang, Y.T, Si, T. | Deposit date: | 2023-02-28 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | RhlA Exhibits Dual Thioesterase and Acyltransferase Activities during Rhamnolipid Biosynthesis Acs Catalysis, 13, 2023
|
|
7DA4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7da4 by Molmil](/molmil-images/mine/7da4) | Cryo-EM structure of amyloid fibril formed by human RIPK3 | Descriptor: | Receptor-interacting serine/threonine-protein kinase 3 | Authors: | Zhao, K, Ma, Y.Y, Sun, Y.P, Li, D, Liu, C. | Deposit date: | 2020-10-14 | Release date: | 2021-04-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.24 Å) | Cite: | The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIPK3. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
3RGQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rgq by Molmil](/molmil-images/mine/3rgq) | Crystal Structure of PTPMT1 in complex with PI(5)P | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, Protein-tyrosine phosphatase mitochondrial 1 | Authors: | Xiao, J, Engel, J.L. | Deposit date: | 2011-04-08 | Release date: | 2011-07-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
8VK2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vk2 by Molmil](/molmil-images/mine/8vk2) | X-ray crystal structure of human IgE 4C8 Fab | Descriptor: | IgE 4C8 heavy chain, IgE 4C8 light chain | Authors: | Khatri, K, Ball, A, Smith, S.A, Champan, M.D, Pomes, A, Chruszcz, M. | Deposit date: | 2024-01-08 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.508 Å) | Cite: | Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2. J.Allergy Clin.Immunol., 2024
|
|
8VK1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vk1 by Molmil](/molmil-images/mine/8vk1) | X-ray crystal structure of human IgE 4C8 Fab complex with Der p 2.0103 | Descriptor: | Der p 2 variant 3, IgE 4C8 heavy chain, IgE 4C8 light chain | Authors: | Khatri, K, Ball, A, Smith, S.A, Champan, M.D, Pomes, A, Chruszcz, M. | Deposit date: | 2024-01-08 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2. J.Allergy Clin.Immunol., 2024
|
|
7VKH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vkh by Molmil](/molmil-images/mine/7vkh) | |
7VKG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vkg by Molmil](/molmil-images/mine/7vkg) | |
3RGO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rgo by Molmil](/molmil-images/mine/3rgo) | Crystal Structure of PTPMT1 | Descriptor: | Protein-tyrosine phosphatase mitochondrial 1, SULFATE ION | Authors: | Xiao, J, Engel, J.L. | Deposit date: | 2011-04-08 | Release date: | 2011-07-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.928 Å) | Cite: | Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
8HIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hit by Molmil](/molmil-images/mine/8hit) | Crystal structure of anti-CTLA-4 humanized IgG1 MAb--JS007 in complex with human CTLA-4 | Descriptor: | Cytotoxic T-lymphocyte protein 4, JS007-VH, JS007-VL | Authors: | Tan, S, Shi, Y, Wang, Q, Gao, G.F, Guan, J, Chai, Y, Qi, J. | Deposit date: | 2022-11-21 | Release date: | 2023-02-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer. Mabs, 15, 2023
|
|
3RER
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rer by Molmil](/molmil-images/mine/3rer) | Crystal structure of E. coli Hfq in complex with AU6A RNA and ADP | Descriptor: | 5'-R(*AP*UP*UP*UP*UP*UP*UP*A)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wang, W.W, Wu, J.H, Shi, Y.Y. | Deposit date: | 2011-04-05 | Release date: | 2011-10-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Cooperation of Escherichia coli Hfq hexamers in DsrA binding. Genes Dev., 25, 2011
|
|
3RES
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3res by Molmil](/molmil-images/mine/3res) | |
6JNL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jnl by Molmil](/molmil-images/mine/6jnl) | REF6 ZnF2-4-NAC004 complex | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*TP*GP*TP*TP*TP*TP*G)-3'), ... | Authors: | Yao, Q.Q, Wu, B.X, Ma, J.B. | Deposit date: | 2019-03-17 | Release date: | 2019-03-27 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | DNA methylation repels targeting of Arabidopsis REF6. Nat Commun, 10, 2019
|
|
8JAR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jar by Molmil](/molmil-images/mine/8jar) | Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-07 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8JAL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jal by Molmil](/molmil-images/mine/8jal) | Structure of CRL2APPBP2 bound with RxxGP degron (dimer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-06 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8JAQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jaq by Molmil](/molmil-images/mine/8jaq) | Structure of CRL2APPBP2 bound with RxxGP degron (tetramer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-06 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
3SRR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3srr by Molmil](/molmil-images/mine/3srr) | S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines | Descriptor: | 3-(2,4-diamino-6-methylquinazolin-7-yl)-4-ethoxybenzaldehyde, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Hilgers, M. | Deposit date: | 2011-07-07 | Release date: | 2011-08-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines. Bioorg.Med.Chem.Lett., 21, 2011
|
|
8JAS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jas by Molmil](/molmil-images/mine/8jas) | Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-07 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8JAU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jau by Molmil](/molmil-images/mine/8jau) | Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (dimer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-07 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8JAV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jav by Molmil](/molmil-images/mine/8jav) | Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (tetramer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-07 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
6JNM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jnm by Molmil](/molmil-images/mine/6jnm) | REF6 ZnF2-4-NAC004-mC3 complex | Descriptor: | DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*GP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*(5CM)P*TP*GP*TP*TP*TP*TP*G)-3'), Lysine-specific demethylase REF6, ... | Authors: | Yao, Q.Q, Wu, B.X, Ma, J.B. | Deposit date: | 2019-03-17 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | DNA methylation repels targeting of Arabidopsis REF6. Nat Commun, 10, 2019
|
|
3SQY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sqy by Molmil](/molmil-images/mine/3sqy) | |
3SR5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sr5 by Molmil](/molmil-images/mine/3sr5) | |
3SRW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3srw by Molmil](/molmil-images/mine/3srw) | S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines | Descriptor: | 7-(2-ethoxynaphthalen-1-yl)-6-methylquinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Hilgers, M. | Deposit date: | 2011-07-07 | Release date: | 2011-08-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines. Bioorg.Med.Chem.Lett., 21, 2011
|
|
6JNN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jnn by Molmil](/molmil-images/mine/6jnn) | REF6 ZnF2-4-NAC004-mC1 complex | Descriptor: | DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*GP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*(5CM)P*TP*CP*TP*GP*TP*TP*TP*TP*G)-3'), Lysine-specific demethylase REF6, ... | Authors: | Yao, Q.Q, Wu, B.X, Ma, J.B. | Deposit date: | 2019-03-17 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | DNA methylation repels targeting of Arabidopsis REF6. Nat Commun, 10, 2019
|
|
3SRQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3srq by Molmil](/molmil-images/mine/3srq) | S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines | Descriptor: | 1-[3-(2,4-diamino-6-methylquinazolin-7-yl)phenyl]ethanone, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Hilgers, M. | Deposit date: | 2011-07-07 | Release date: | 2011-08-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines. Bioorg.Med.Chem.Lett., 21, 2011
|
|