3ATU
 
 | | Crystal structure of human Hsp70 NBD in the ADP- and Mg ion-bound state | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A/1B, ... | | Authors: | Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2011-01-13 | | Release date: | 2011-12-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Biochemical and structural studies on the high affinity of Hsp70 for ADP.
Protein Sci., 20, 2011
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3AU3
 | | Crystal structure of armadillo repeat domain of APC | | Descriptor: | Adenomatous polyposis coli protein | | Authors: | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2011-01-28 | | Release date: | 2011-11-02 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68
Structure, 19, 2011
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3AVS
 | | Catalytic fragment of UTX/KDM6A bound with N-oxyalylglycine, and Ni(II) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 6A, ... | | Authors: | Sengoku, T, Yokoyama, S. | | Deposit date: | 2011-03-07 | | Release date: | 2011-10-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A
Genes Dev., 25, 2011
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3AVR
 | | Catalytic fragment of UTX/KDM6A bound with histone H3K27me3 peptide, N-oxyalylglycine, and Ni(II) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Histone H3, ... | | Authors: | Sengoku, T, Yokoyama, S. | | Deposit date: | 2011-03-07 | | Release date: | 2011-10-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.803 Å) | | Cite: | Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A
Genes Dev., 25, 2011
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2E1O
 | | Solution structure of RSGI RUH-028, a homeobox domain from human cDNA | | Descriptor: | Homeobox protein PRH | | Authors: | Nakamura, A, Ohnishi, S, Abe, T, Nameki, N, Tochio, N, Koshiba, S, Kigawa, T, Yokoyama, S, Kawaii, S, Hirota, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-10-27 | | Release date: | 2006-11-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RSGI RUH-028, a homeobox domain from human cDNA
To be Published
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3AQA
 | | Crystal structure of the human BRD2 BD1 bromodomain in complex with a BRD2-interactive compound, BIC1 | | Descriptor: | 1-[2-(1H-benzimidazol-2-ylsulfanyl)ethyl]-3-methyl-1,3-dihydro-2H-benzimidazole-2-thione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bromodomain-containing protein 2 | | Authors: | Umehara, T, Nakamura, Y, Terada, T, Shirouzu, M, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2010-10-27 | | Release date: | 2011-05-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Real-Time Imaging of Histone H4K12-Specific Acetylation Determines the Modes of Action of Histone Deacetylase and Bromodomain Inhibitors
Chem.Biol., 18, 2011
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2E19
 | | Solution structure of the homeobox domain from human NIL-2-A zinc finger protein, transcription factor 8 | | Descriptor: | Transcription factor 8 | | Authors: | Ohnishi, S, Tochio, N, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-10-19 | | Release date: | 2007-04-24 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the homeobox domain from human NIL-2-A zinc finger protein, transcription factor 8
To be Published
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1ZPW
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2Z32
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2E29
 | | Solution structure of the GUCT domain from human ATP-dependent RNA helicase DDX50, DEAD box protein 50 | | Descriptor: | ATP-dependent RNA helicase DDX50 | | Authors: | Ohnishi, S, Paakkonen, K, Guntert, P, Sato, M, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-11-10 | | Release date: | 2007-05-15 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the GUCT domain from human RNA helicase II/Gubeta reveals the RRM fold, but implausible RNA interactions
Proteins, 74, 2008
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2EB3
 | | Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP | | Descriptor: | Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Senba, K, Yamamoto, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-02-06 | | Release date: | 2008-02-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.84 Å) | | Cite: | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 2012
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3AKZ
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3AB3
 | | Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(k) subunit alpha, Guanine nucleotide-binding protein subunit alpha-13, ... | | Authors: | Kukimoto-Niino, M, Mishima, C, Shirouzu, M, Kozasa, T, Yokoyama, S. | | Deposit date: | 2009-11-30 | | Release date: | 2010-12-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex.
J.Biol.Chem., 286, 2011
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2ZCC
 | | Ubiquitin crystallized under high pressure | | Descriptor: | Ubiquitin, ZINC ION | | Authors: | Kitahara, R, Tanaka, T, Yamashita, M, Araya, K, Yokoyama, S, Akasaka, K, Taniguchi, Y, Kato, M. | | Deposit date: | 2007-11-08 | | Release date: | 2007-11-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of Ubiquitin crystallized under high pressure
to be published
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2ZET
 | | Crystal structure of the small GTPase Rab27B complexed with the Slp homology domain of Slac2-a/melanophilin | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Melanophilin, ... | | Authors: | Kukimoto-Niino, M, Sakamoto, A, Kanno, E, Hanawa-Suetsugu, K, Terada, T, Shirouzu, M, Fukuda, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-12-17 | | Release date: | 2008-09-30 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases.
Structure, 16, 2008
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2ZUL
 | | Crystal structure of Thermus thermophilus 16S rRNA methyltransferase RsmC (TTHA0533) in complex with cofactor S-adenosyl-L-Methionine | | Descriptor: | Probable ribosomal RNA small subunit methyltransferase, S-ADENOSYLMETHIONINE | | Authors: | Wang, H, Kawazoe, M, Tatsuguchi, A, Naoe, C, Takemoto, C, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2008-10-21 | | Release date: | 2009-10-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of Thermus thermophilus 16S rRNA methyltransferase RsmC (TTHA0533) in complex with cofactor S-adenosyl-L-Methionine
To be Published
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2Z34
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2Z3F
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2ZP1
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2ZIO
 | | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with AlocLys-AMP and PNP | | Descriptor: | 5'-O-[(S)-({(2S)-2-amino-6-[(propoxycarbonyl)amino]hexanoyl}oxy)(hydroxy)phosphoryl]adenosine, IMIDODIPHOSPHORIC ACID, Pyrrolysyl-tRNA synthetase | | Authors: | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2008-02-19 | | Release date: | 2008-12-02 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification
Chem.Biol., 15, 2008
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1Z54
 | | Crystal structure of a hypothetical protein TT1821 from Thermus thermophilus | | Descriptor: | GLYCEROL, probable thioesterase | | Authors: | Ihsanawati, Kaminishi, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-03-17 | | Release date: | 2005-09-17 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of a hypothetical protein TT1821 from Thermus thermophilus
TO BE PUBLISHED
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3AL0
 | | Crystal structure of the glutamine transamidosome from Thermotoga maritima in the glutamylation state. | | Descriptor: | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Glutamyl-tRNA(Gln) amidotransferase subunit A, Glutamyl-tRNA(Gln) amidotransferase subunit C,Linker,Glutamate--tRNA ligase 2, ... | | Authors: | Ito, T, Yokoyama, S. | | Deposit date: | 2010-07-19 | | Release date: | 2010-09-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.368 Å) | | Cite: | Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions.
Nature, 467, 2010
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2DWV
 | | Solution structure of the second WW domain from mouse salvador homolog 1 protein (mWW45) | | Descriptor: | Salvador homolog 1 protein | | Authors: | Ohnishi, S, Kigawa, T, Koshiba, S, Tomizawa, T, Sato, M, Tochio, N, Inoue, M, Harada, T, Watanabe, S, Guntert, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-08-17 | | Release date: | 2007-02-17 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of an atypical WW domain in a novel beta-clam-like dimeric form
Febs Lett., 581, 2007
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2ZG6
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3AWI
 | | Bifunctional tRNA modification enzyme MnmC from Escherichia coli | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein mnmC | | Authors: | Kitamura, A, Sengoku, T, Nishimoto, M, Yokoyama, S, Bessho, Y. | | Deposit date: | 2011-03-23 | | Release date: | 2011-06-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli
Protein Sci., 2011
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