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6JJH
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BU of 6jjh by Molmil
Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4
Descriptor: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, POTASSIUM ION, RNA (5'-R(*GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3')
Authors:Zhang, Y.S, EI Omari, K, Duman, R, Wagner, A, Parkinson, G.N, Wei, D.G.
Deposit date:2019-02-25
Release date:2020-02-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
6JJF
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BU of 6jjf by Molmil
Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex
Descriptor: COBALT HEXAMMINE(III), DNA (5'-D(*GP*GP*CP*TP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3'), POTASSIUM ION, ...
Authors:Zhang, Y.S, EI Omari, K, Duman, R, Wagner, A, Parkinson, G.N, Wei, D.G.
Deposit date:2019-02-25
Release date:2020-02-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
7R1O
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BU of 7r1o by Molmil
p62-ZZ domain of the human sequestosome in complex with dusquetide
Descriptor: Dusquetide, Sequestosome-1, ZINC ION
Authors:Hakansson, M, Hansson, M, Logan, D.T, Rozek, A, Donini, O.
Deposit date:2022-02-03
Release date:2022-05-18
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Dusquetide modulates innate immune response through binding to p62.
Structure, 30, 2022
7DQZ
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BU of 7dqz by Molmil
Crystal structure of SARS 3C-like protease in apo form
Descriptor: 3C-like proteinase
Authors:Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J.
Deposit date:2020-12-24
Release date:2021-09-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
7EO7
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BU of 7eo7 by Molmil
Crystal structure of HCoV-NL63 3C-like protease in complex with an inhibitor Shikonin
Descriptor: 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase
Authors:Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:2021-04-21
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.24916625 Å)
Cite:Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
7EO8
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BU of 7eo8 by Molmil
Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin
Descriptor: 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase
Authors:Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J.
Deposit date:2021-04-21
Release date:2021-10-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2808516 Å)
Cite:Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
6SR6
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BU of 6sr6 by Molmil
Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein, ...
Authors:Valentin Gese, G, Lapouge, K, Kopp, J, Sinning, I.
Deposit date:2019-09-05
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb.
Nat Commun, 11, 2020
8K6Q
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BU of 8k6q by Molmil
Crystal structure of HOIL-1L LTM domain
Descriptor: RanBP-type and C3HC4-type zinc finger-containing protein 1
Authors:Yan, Z, Pan, L.F.
Deposit date:2023-07-25
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN.
Biochem.Biophys.Res.Commun., 689, 2023
8K6P
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BU of 8k6p by Molmil
Crystal structure of SHARPIN LTM motif
Descriptor: Sharpin
Authors:Yan, Z, Pan, L.F.
Deposit date:2023-07-25
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN.
Biochem.Biophys.Res.Commun., 689, 2023
6TQI
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BU of 6tqi by Molmil
I-MOTIF STRUCTURE FORMED FROM THE C STRAND OF A HUMAN TELOMERE FRAGMENT
Descriptor: DNA (5'-*TP*AP*AP*CP*CP*CP*TP*AP*A-3')
Authors:Parkinson, G.N, Wagner, A, Viladoms-Claverol, J, Duman, R, El-Omari, K.
Deposit date:2019-12-16
Release date:2020-06-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
8TCC
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BU of 8tcc by Molmil
GTP Cyclohydrolase-IB with dehydrocostus lactone
Descriptor: 1,2-ETHANEDIOL, GTP cyclohydrolase FolE2, MANGANESE (II) ION, ...
Authors:McWhorter, K.L, Amaya Lopez, C.Y, Davis, K.M.
Deposit date:2023-06-30
Release date:2024-07-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Combatting melioidosis with chemical synthetic lethality
To be published
3IAX
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BU of 3iax by Molmil
The crystal structure of the TolB box of Colicin A in complex with TolB reveals important differences in the recruitment of the common TolB translocation portal used by group A colicins
Descriptor: CALCIUM ION, Colicin-A, GLYCEROL, ...
Authors:Li, C.
Deposit date:2009-07-15
Release date:2009-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of the TolB box of colicin A in complex with TolB reveals important differences in the recruitment of the common TolB translocation portal used by group A colicins.
Mol.Microbiol., 75, 2009
8CZ9
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BU of 8cz9 by Molmil
Crystal Structure of the E372K LNK SH2 Domain mutant in Complex with a JAK2 pY813 Phosphopeptide
Descriptor: CHLORIDE ION, JAK2 pY813 phosphopeptide, SH2B adapter protein 3
Authors:Morris, R, Kershaw, N.J, Babon, J.J.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity.
J.Exp.Med., 221, 2024
2L7Z
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BU of 2l7z by Molmil
NMR Structure of A13 homedomain
Descriptor: Homeobox protein Hox-A13
Authors:Ames, J.
Deposit date:2010-12-27
Release date:2011-11-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for sequence specific DNA binding and protein dimerization of HOXA13.
Plos One, 6, 2011
7Y56
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BU of 7y56 by Molmil
Crystal structure of NS1 nuclease domain in P41212 space group
Descriptor: GLYCEROL, NS1 protein
Authors:Zhang, X.Y, Gan, J.H.
Deposit date:2022-06-16
Release date:2023-07-05
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein.
Comput Struct Biotechnol J, 20, 2022
7Y57
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BU of 7y57 by Molmil
Crystal structure of NS1 nuclease domain in P21 space group
Descriptor: NS1 protein, PHOSPHATE ION
Authors:Zhang, X.Y, Gan, J.H.
Deposit date:2022-06-16
Release date:2023-07-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.183 Å)
Cite:Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein.
Comput Struct Biotechnol J, 20, 2022
7XQV
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BU of 7xqv by Molmil
The complex of nanobody Rh57 binding to GTP-bound RhoA active form
Descriptor: ALANINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Zhang, Y.R, Liu, R, Ding, Y.
Deposit date:2022-05-09
Release date:2022-07-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural insights into the binding of nanobody Rh57 to active RhoA-GTP.
Biochem.Biophys.Res.Commun., 616, 2022
7YIR
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BU of 7yir by Molmil
Crystal structure of N-terminal PH domain of ARAP3 protein from human
Descriptor: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, DI(HYDROXYETHYL)ETHER
Authors:Zhang, Y.J, Liu, Y.R, Wu, B.
Deposit date:2022-07-18
Release date:2023-05-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
7YIS
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BU of 7yis by Molmil
Crystal structure of N-terminal PH domain of ARAP3 protein in complex with inositol 1,3,4,5-tetrakisphosphate
Descriptor: (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Zhang, Y.J, Liu, Y.R, Wu, B.
Deposit date:2022-07-18
Release date:2023-05-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
7WFY
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BU of 7wfy by Molmil
Crystal Structure of the VAV2 SH2 domain in complex with APP phosphorylated peptide
Descriptor: Amyloid beta A4 protein-binding family B member 1 (protein), Guanine nucleotide exchange factor VAV2
Authors:Zhang, Y.J, Liu, Y.R, Wu, B.
Deposit date:2021-12-27
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.449 Å)
Cite:Vav2 is a novel APP-interacting protein that regulates APP protein level.
Sci Rep, 12, 2022
7D06
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BU of 7d06 by Molmil
Cryo EM structure of the nucleotide free Acinetobacter MlaFEDB complex
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, ABC transporter ATP-binding protein, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7D0A
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BU of 7d0a by Molmil
Acinetobacter MlaFEDB complex in ADP-vanadate trapped Vclose conformation
Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-DIPHOSPHATE, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7D09
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BU of 7d09 by Molmil
Acinetobacter MlaFEDB complex in ATP-bound Vtrans2 conformation
Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7D08
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BU of 7d08 by Molmil
Acinetobacter MlaFEDB complex in ATP-bound Vtrans1 conformation
Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
8G6C
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BU of 8g6c by Molmil
GTP Cyclohydrolase-IB with manganese
Descriptor: 1,2-ETHANEDIOL, GTP cyclohydrolase FolE2, MANGANESE (II) ION
Authors:McWhorter, K.L, Amaya Lopez, C.Y, Davis, K.M.
Deposit date:2023-02-14
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Combatting melioidosis with chemical synthetic lethality
To Be Published

222926

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