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8OOI
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BU of 8ooi by Molmil
Full composite cryo-EM map of p97/VCP in ADP.Pi state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Cheng, T.C, Sakata, E, Schuetz, A.K.
Deposit date:2023-04-05
Release date:2024-01-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Characterizing ATP processing by the AAA+ protein p97 at the atomic level.
Nat.Chem., 16, 2024
8B3X
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BU of 8b3x by Molmil
High resolution crystal structure of dimeric SUDV VP40
Descriptor: Matrix protein VP40
Authors:Werner, A.-D, Norris, M, Saphire, E.O, Becker, S.
Deposit date:2022-09-17
Release date:2023-06-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.531 Å)
Cite:The C-terminus of Sudan ebolavirus VP40 contains a functionally important CX n C motif, a target for redox modifications.
Structure, 31, 2023
8UBH
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BU of 8ubh by Molmil
Solution NMR structure of KaiB variant from Thermosynechococcus elongatus vestitus (KaiBTV-4)
Descriptor: Circadian oscillation regulator
Authors:Ojoawo, A, Wayment-Steele, H.K, Kern, D.
Deposit date:2023-09-23
Release date:2023-10-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Predicting multiple conformations via sequence clustering and AlphaFold2.
Nature, 625, 2024
8B1P
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BU of 8b1p by Molmil
Crystal structure of SUDV VP40 CCS mutant
Descriptor: Matrix protein VP40
Authors:Werner, A.-D, Becker, S.
Deposit date:2022-09-11
Release date:2023-06-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The C-terminus of Sudan ebolavirus VP40 contains a functionally important CX n C motif, a target for redox modifications.
Structure, 31, 2023
8B1O
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BU of 8b1o by Molmil
Crystal structure of SUDV VP40 C314S mutant
Descriptor: Matrix protein VP40
Authors:Werner, A.-D, Becker, S.
Deposit date:2022-09-11
Release date:2023-06-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The C-terminus of Sudan ebolavirus VP40 contains a functionally important CX n C motif, a target for redox modifications.
Structure, 31, 2023
7PV1
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BU of 7pv1 by Molmil
Crystal structure of the dimeric mitofilin domain of Mic60 in complex with the CHCH domain of Mic19
Descriptor: MICOS complex subunit MIC60 fused to MIC19, TETRAETHYLENE GLYCOL
Authors:Funck, K, Bock-Bierbaum, T, Daumke, O.
Deposit date:2021-10-01
Release date:2022-09-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural insights into crista junction formation by the Mic60-Mic19 complex.
Sci Adv, 8, 2022
7PUZ
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BU of 7puz by Molmil
Crystal structure of the Mic60 coiled coil domain
Descriptor: MICOS complex subunit MIC60
Authors:Bock-Bierbaum, T, Funck, K, Daumke, O.
Deposit date:2021-10-01
Release date:2022-09-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.842 Å)
Cite:Structural insights into crista junction formation by the Mic60-Mic19 complex.
Sci Adv, 8, 2022
7PV0
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BU of 7pv0 by Molmil
Crystal structure of a Mic60-Mic19 fusion protein
Descriptor: MICOS complex subunit MIC60,MICOS complex subunit MIC60-MIC19,Mic60-Mic19, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
Authors:Funck, K, Bock-Bierbaum, T, Daumke, O.
Deposit date:2021-10-01
Release date:2022-09-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural insights into crista junction formation by the Mic60-Mic19 complex.
Sci Adv, 8, 2022
4MP0
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BU of 4mp0 by Molmil
Structure of a second nuclear PP1 Holoenzyme, crystal form 2
Descriptor: GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Choy, M.S, Hieke, M, Peti, W, Page, R.
Deposit date:2013-09-12
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1003 Å)
Cite:Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MOY
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BU of 4moy by Molmil
Structure of a second nuclear PP1 Holoenzyme, crystal form 1
Descriptor: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ...
Authors:Choy, M.S, Hieke, M, Peti, W, Page, R.
Deposit date:2013-09-12
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1953 Å)
Cite:Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CSV
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BU of 4csv by Molmil
Tyrosine kinase AS - a common ancestor of Src and Abl bound to Gleevec
Descriptor: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, SRC-ABL TYROSINE KINASE ANCESTOR
Authors:Kutter, S, Wilson, C, Cruz, L, Agafonov, R.V, Hoemberger, M.S, Zorba, A, Kern, D.
Deposit date:2014-03-10
Release date:2015-03-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Kinase Dynamics. Using Ancient Protein Kinases to Unravel a Modern Cancer Drug'S Mechanism.
Science, 347, 2015
4MOV
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BU of 4mov by Molmil
1.45 A Resolution Crystal Structure of Protein Phosphatase 1
Descriptor: CHLORIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Choy, M.S, Peti, W, Page, R.
Deposit date:2013-09-12
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4503 Å)
Cite:Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code.
Proc.Natl.Acad.Sci.USA, 111, 2014
5G15
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BU of 5g15 by Molmil
Structure Aurora A (122-403) bound to activating monobody Mb1 and AMPPCP
Descriptor: AURORA A KINASE, MAGNESIUM ION, MB1 MONOBODY, ...
Authors:Zorba, A, Kutter, S, Kern, D, Koide, S, Koide, A.
Deposit date:2016-03-23
Release date:2018-03-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Allosteric modulation of a human protein kinase with monobodies.
Proc.Natl.Acad.Sci.USA, 116, 2019
5G41
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BU of 5g41 by Molmil
Crystal structure of adenylate kinase ancestor 4 with Zn, Mg and Ap5A bound
Descriptor: ADENYLATE KINSE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
Authors:Nguyen, V, Kutter, S, English, J, Kern, D.
Deposit date:2016-05-03
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Evolutionary drivers of thermoadaptation in enzyme catalysis.
Science, 355, 2017
5G40
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BU of 5g40 by Molmil
Crystal structure of adenylate kinase ancestor 4 with Zn and AMP-ADP bound
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINSE, ...
Authors:Nguyen, V, Kutter, S, English, J, Kern, D.
Deposit date:2016-05-03
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Evolutionary drivers of thermoadaptation in enzyme catalysis.
Science, 355, 2017
5G3Y
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BU of 5g3y by Molmil
Crystal structure of adenylate kinase ancestor 1 with Zn and ADP bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINSE, ZINC ION
Authors:Nguyen, V, Kutter, S, English, J, Kern, D.
Deposit date:2016-05-03
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Evolutionary drivers of thermoadaptation in enzyme catalysis.
Science, 355, 2017
5G3Z
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BU of 5g3z by Molmil
Crystal structure of adenylate kinase ancestor 3 with Zn, Mg and Ap5A bound
Descriptor: ADENYLATE KINSE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
Authors:Nguyen, V, Kutter, S, English, J, Kern, D.
Deposit date:2016-05-03
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Evolutionary drivers of thermoadaptation in enzyme catalysis.
Science, 355, 2017
4OKA
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BU of 4oka by Molmil
Structural-, Kinetic- and Docking Studies of Artificial Imine Reductases Based on the Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis
Descriptor: IRIDIUM ION, Streptavidin, [N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamidato]iridium(III)
Authors:Schirmer, T, Heinisch, T.
Deposit date:2014-01-22
Release date:2014-11-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.505 Å)
Cite:Structural, Kinetic, and Docking Studies of Artificial Imine Reductases Based on Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis
J.Am.Chem.Soc., 136, 2014
5BX0
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BU of 5bx0 by Molmil
An Automated Microscale Thermophoresis Screening Approach for Fragment-Based Lead Discovery
Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, ethyl 2H-indazole-5-carboxylate
Authors:Vallee, F, Steier, V, Rak, A.
Deposit date:2015-06-08
Release date:2015-12-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:An Automated Microscale Thermophoresis Screening Approach for Fragment-Based Lead Discovery.
J Biomol Screen, 21, 2016
4H1U
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BU of 4h1u by Molmil
Nucleotide-free human dynamin-1-like protein GTPase-GED fusion
Descriptor: CITRATE ANION, Dynamin-1-like protein
Authors:Wenger, J, Klinglmayr, E, Puehringer, S, Goettig, P.
Deposit date:2012-09-11
Release date:2013-08-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional Mapping of Human Dynamin-1-Like GTPase Domain Based on X-ray Structure Analyses.
Plos One, 8, 2013

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