6ER3
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![BU of 6er3 by Molmil](/molmil-images/mine/6er3) | Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,3 sialyllactose | Descriptor: | BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | Authors: | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | Deposit date: | 2017-10-16 | Release date: | 2018-05-02 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus. Nat Commun, 8, 2017
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6EFB
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![BU of 6efb by Molmil](/molmil-images/mine/6efb) | GspB Siglec domain | Descriptor: | CALCIUM ION, GLYCEROL, SK150 siglec + Unique, ... | Authors: | Iverson, T.M. | Deposit date: | 2018-08-16 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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6EF7
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![BU of 6ef7 by Molmil](/molmil-images/mine/6ef7) | GspB Siglec domain | Descriptor: | CALCIUM ION, Platelet binding protein GspB | Authors: | Iverson, T.M. | Deposit date: | 2018-08-16 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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6EFA
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![BU of 6efa by Molmil](/molmil-images/mine/6efa) | GspB Siglec + Unique domains | Descriptor: | CALCIUM ION, Platelet binding protein GspB | Authors: | Iverson, T.M. | Deposit date: | 2018-08-16 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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6ER4
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![BU of 6er4 by Molmil](/molmil-images/mine/6er4) | Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,6 sialyllactose | Descriptor: | BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | Authors: | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | Deposit date: | 2017-10-16 | Release date: | 2018-05-02 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus. Nat Commun, 8, 2017
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6EF9
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![BU of 6ef9 by Molmil](/molmil-images/mine/6ef9) | GspB Siglec domain | Descriptor: | FORMIC ACID, Platelet binding protein GspB - Siglec domain, SODIUM ION | Authors: | Iverson, T.M. | Deposit date: | 2018-08-16 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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6EFD
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![BU of 6efd by Molmil](/molmil-images/mine/6efd) | Hsa Siglec and Unique domains in complex with the sialyl T antigen trisaccharide | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, SODIUM ION, Streptococcal hemagglutinin | Authors: | Iverson, T.M. | Deposit date: | 2018-08-16 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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3UIM
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![BU of 3uim by Molmil](/molmil-images/mine/3uim) | |
6ER2
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![BU of 6er2 by Molmil](/molmil-images/mine/6er2) | |
1X18
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![BU of 1x18 by Molmil](/molmil-images/mine/1x18) | Contact sites of ERA GTPase on the THERMUS THERMOPHILUS 30S SUBUNIT | Descriptor: | 30S ribosomal protein S11, 30S ribosomal protein S18, 30S ribosomal protein S2, ... | Authors: | Sharma, M.R, Barat, C, Agrawal, R.K. | Deposit date: | 2005-04-02 | Release date: | 2005-05-17 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (13.5 Å) | Cite: | Interaction of Era with the 30S Ribosomal Subunit Implications for 30S Subunit Assembly Mol.Cell, 18, 2005
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6EFF
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![BU of 6eff by Molmil](/molmil-images/mine/6eff) | NCTC10712 | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Iverson, T.M. | Deposit date: | 2018-08-16 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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3SE9
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![BU of 3se9 by Molmil](/molmil-images/mine/3se9) | Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120 | Descriptor: | (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kwong, P.D, Zhou, T. | Deposit date: | 2011-06-10 | Release date: | 2011-08-10 | Last modified: | 2021-04-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333, 2011
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6FC5
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![BU of 6fc5 by Molmil](/molmil-images/mine/6fc5) | Bik1 CAP-Gly domain | Descriptor: | Microtubule-associated protein | Authors: | Kumar, A, Stangier, M.M, Steinmetz, M.O. | Deposit date: | 2017-12-20 | Release date: | 2018-04-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structure-Function Relationship of the Bik1-Bim1 Complex. Structure, 26, 2018
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1X1L
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![BU of 1x1l by Molmil](/molmil-images/mine/1x1l) | Interaction of ERA,a GTPase protein, with the 3'minor domain of the 16S rRNA within the THERMUS THERMOPHILUS 30S subunit. | Descriptor: | GTP-binding protein era, RNA (130-MER) | Authors: | Sharma, M.R, Barat, C, Agrawal, R.K. | Deposit date: | 2005-04-06 | Release date: | 2005-05-17 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (13.5 Å) | Cite: | Interaction of Era with the 30S Ribosomal Subunit Implications for 30S Subunit Assembly Mol.Cell, 18, 2005
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6FC6
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![BU of 6fc6 by Molmil](/molmil-images/mine/6fc6) | |
5U4R
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![BU of 5u4r by Molmil](/molmil-images/mine/5u4r) | Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 53-1A09 Fab. | Descriptor: | VRC 315 53-1A09 Fab Heavy chain, VRC 315 53-1A09 Fab Light chain | Authors: | Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D. | Deposit date: | 2016-12-05 | Release date: | 2017-11-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.762 Å) | Cite: | Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2, 2017
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5TY6
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![BU of 5ty6 by Molmil](/molmil-images/mine/5ty6) | Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 13-1b02 Fab. | Descriptor: | GLYCEROL, VRC 315 13-1b02 Fab Heavy chain, VRC 315 13-1b02 Fab Light chain | Authors: | Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D. | Deposit date: | 2016-11-18 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.361 Å) | Cite: | Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2, 2017
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2I4X
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![BU of 2i4x by Molmil](/molmil-images/mine/2i4x) | HIV-1 Protease I84V, L90M with GS-8374 | Descriptor: | DIETHYL ({4-[(2S,3R)-2-({[(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YLOXY]CARBONYL}AMINO)-3-HYDROXY-4-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}BUTYL]PHENOXY}METHYL)PHOSPHONATE, Protease | Authors: | Hatada, M. | Deposit date: | 2006-08-22 | Release date: | 2007-08-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring. J.Mol.Biol., 363, 2006
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2QP8
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![BU of 2qp8 by Molmil](/molmil-images/mine/2qp8) | Structure of BACE Bound to SCH734723 | Descriptor: | Beta-secretase 1, D(-)-TARTARIC ACID, N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-[(2R,4S)-4-ETHOXYPIPERIDIN-2-YL]-2-HYDROXYETHYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | Authors: | Strickland, C.O, Iserloh, U. | Deposit date: | 2007-07-23 | Release date: | 2008-03-11 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Potent pyrrolidine- and piperidine-based BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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2QK5
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![BU of 2qk5 by Molmil](/molmil-images/mine/2qk5) | Structure of BACE1 bound to SCH626485 | Descriptor: | Beta-secretase 1, N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | Authors: | Strickland, C.O, Iserloh, U. | Deposit date: | 2007-07-10 | Release date: | 2008-03-11 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Potent pyrrolidine- and piperidine-based BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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2QMF
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![BU of 2qmf by Molmil](/molmil-images/mine/2qmf) | Structure of BACE Bound to SCH735310 | Descriptor: | Beta-secretase 1, D(-)-TARTARIC ACID, N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-[(2R,4R)-4-PHENOXYPYRROLIDIN-2-YL]ETHYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | Authors: | Strickland, C.O, Iserloh, U. | Deposit date: | 2007-07-16 | Release date: | 2008-03-11 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Potent pyrrolidine- and piperidine-based BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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2QVR
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![BU of 2qvr by Molmil](/molmil-images/mine/2qvr) | E. coli Fructose-1,6-bisphosphatase: Citrate, Fru-2,6-P2, and Mg2+ bound | Descriptor: | 2,6-di-O-phosphono-beta-D-fructofuranose, CITRIC ACID, Fructose-1,6-bisphosphatase, ... | Authors: | Hines, J.K, Fromm, H.J, Honzatko, R.B. | Deposit date: | 2007-08-08 | Release date: | 2007-10-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structures of Mammalian and Bacterial Fructose-1,6-bisphosphatase Reveal the Basis for Synergism in AMP/Fructose 2,6-Bisphosphate Inhibition. J.Biol.Chem., 282, 2007
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2R2Y
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![BU of 2r2y by Molmil](/molmil-images/mine/2r2y) | |
2QMD
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![BU of 2qmd by Molmil](/molmil-images/mine/2qmd) | Structure of BACE Bound to SCH722924 | Descriptor: | Beta-secretase 1, D(-)-TARTARIC ACID, N'-[(1S,2R)-2-[(2R,4R)-4-(BENZYLOXY)PYRROLIDIN-2-YL]-1-(3,5-DIFLUOROBENZYL)-2-HYDROXYETHYL]-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | Authors: | Strickland, C.O, Iserloh, U. | Deposit date: | 2007-07-16 | Release date: | 2008-03-11 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Potent pyrrolidine- and piperidine-based BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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3CIC
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![BU of 3cic by Molmil](/molmil-images/mine/3cic) | Structure of BACE Bound to SCH709583 | Descriptor: | Beta-secretase 1, D(-)-TARTARIC ACID, N'-[(1S,2S)-2-[(2S)-4-benzyl-3-oxopiperazin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | Authors: | Strickland, C, Cumming, J. | Deposit date: | 2008-03-11 | Release date: | 2008-06-10 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors Bioorg.Med.Chem.Lett., 18, 2008
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