6EFD

Hsa Siglec and Unique domains in complex with the sialyl T antigen trisaccharide

Summary for 6EFD

• Entry DOI: 10.2210/pdb6efd/pdb
• Related: 5IUC 6EF7 6EF9 6EFA 6EFB 6EFC 6EFF 6EFI
• Descriptor: Streptococcal hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, SODIUM ION, ... (4 entities in total)
• Functional Keywords: lectin, sugar binding protein
• Biological source: Streptococcus gordonii str. Challis
• Total number of polymer chains: 1
• Total formula weight: 26557.97

Authors

Iverson, T.M. (deposition date: 2018-08-16, release date: 2020-02-19, Last modification date: 2022-06-01)

• Primary citation: Bensing, B.A.,Stubbs, H.E.,Agarwal, R.,Yamakawa, I.,Luong, K.,Solakyildirim, K.,Yu, H.,Hadadianpour, A.,Castro, M.A.,Fialkowski, K.P.,Morrison, K.M.,Wawrzak, Z.,Chen, X.,Lebrilla, C.B.,Baudry, J.,Smith, J.C.,Sullam, P.M.,Iverson, T.M.; Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation.; Nat Commun, 13:2753-2753, 2022; PubMed: 35585145; DOI: 10.1038/s41467-022-30509-y

Experimental method

X-RAY DIFFRACTION (1.85 Å)