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8KGM
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BU of 8kgm by Molmil
Structure of African swine fever virus topoisomerase II in complex with dsDNA
Descriptor: DNA (38-MER), DNA topoisomerase 2
Authors:Cong, J, Xin, Y, Li, X, Chen, Y.
Deposit date:2023-08-19
Release date:2024-04-03
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural insights into the DNA topoisomerase II of the African swine fever virus.
Nat Commun, 15, 2024
8KGP
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BU of 8kgp by Molmil
Structure of African swine fever virus topoisomerase II in complex with dsDNA
Descriptor: DNA topoisomerase 2
Authors:Cong, J, Xin, Y, Li, X, Chen, Y.
Deposit date:2023-08-19
Release date:2024-04-03
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into the DNA topoisomerase II of the African swine fever virus.
Nat Commun, 15, 2024
8KGQ
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BU of 8kgq by Molmil
Structure of African swine fever virus topoisomerase II in complex with dsDNA
Descriptor: DNA (38-MER), DNA topoisomerase 2
Authors:Cong, J, Xin, Y, Li, X, Chen, Y.
Deposit date:2023-08-19
Release date:2024-04-03
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structural insights into the DNA topoisomerase II of the African swine fever virus.
Nat Commun, 15, 2024
7JNT
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BU of 7jnt by Molmil
CRYSTAL STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE 2 (ROCK2) IN COMPLEX WITH A POTENT AND SELECTIVE DUAL ROCK INHIBITOR
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, N-[(3-methoxyphenyl)methyl]-5H-[1]benzopyrano[3,4-c]pyridine-8-carboxamide, ...
Authors:Muckelbauer, J.K.
Deposit date:2020-08-05
Release date:2020-09-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.214 Å)
Cite:Identification of 5H-chromeno[3,4-c]pyridine and 6H-isochromeno[3,4-c]pyridine derivatives as potent and selective dual ROCK inhibitors.
Bioorg.Med.Chem.Lett., 30, 2020
7Y0I
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BU of 7y0i by Molmil
Solution structures of ASH1L PHD domain in complex with H3K4me2 peptide
Descriptor: ALA-ARG-THR-MLY-GLN-THR-ALA-ARG-LYS-SER-THR-GLY-GLY-LYS-ALA, Histone-lysine N-methyltransferase ASH1L, ZINC ION
Authors:Yu, M, Zeng, L.
Deposit date:2022-06-05
Release date:2022-10-12
Method:SOLUTION NMR
Cite:Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
Front Oncol, 12, 2022
7JY5
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BU of 7jy5 by Molmil
Structure of human p97 in complex with ATPgammaS and Npl4/Ufd1 (masked around p97)
Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
Authors:Pan, M, Yu, Y, Liu, L, Zhao, M.
Deposit date:2020-08-28
Release date:2021-01-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative.
Nat Commun, 12, 2021
7YHQ
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BU of 7yhq by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with a covalent-linked reaction intermediate at 3.9 Angstroms resolution
Descriptor: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1
Authors:Du, X, Du, J.
Deposit date:2022-07-14
Release date:2022-11-30
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
7YHP
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BU of 7yhp by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with 5mC-dsDNA at 3.1 Angstroms resolution
Descriptor: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,REPRESSOR OF SILENCING 1,DNA glycosylase/AP lyase ROS1
Authors:Du, X, Du, J.
Deposit date:2022-07-14
Release date:2022-11-30
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
8AGF
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BU of 8agf by Molmil
Crystal structure of human Thiosulfate sulfurtransferase amino acids 2-297
Descriptor: Thiosulfate sulfurtransferase
Authors:Goor, H.v, Grove, M.R, AL-Dahmani, Z.m.
Deposit date:2022-07-19
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The crystal structure of human Thiosulfate sulfurtransferase
To Be Published
7K93
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BU of 7k93 by Molmil
DENV2 NS1 in complex with neutralizing 2B7 single chain Fab variable region (scFv)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 single chain fab variable region, Non-structural protein 1
Authors:Akey, D.L, Smith, J.L.
Deposit date:2020-09-28
Release date:2020-12-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.
Science, 371, 2021
4WXI
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BU of 4wxi by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR trans-N-{(1S)-1-[4-(3-amino-2H-indazol-6-yl)pyridin-2-yl]-2-phenylethyl}-4-(aminomethyl)cyclohexanecarboxamide
Descriptor: 1,2-ETHANEDIOL, COAGULATION FACTOR XI, LIGHT CHAIN, ...
Authors:Wei, A.
Deposit date:2014-11-13
Release date:2015-01-28
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Pyridine and pyridinone-based factor XIa inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
7CVQ
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BU of 7cvq by Molmil
crystal structure of Arabidopsis CO CCT domain in complex with NF-YB2/YC3 and FT CORE1 DNA
Descriptor: Chimera of Nuclear transcription factor Y subunit C-3 and Zinc finger protein CONSTANS, FT CORE1 DNA forward strand, FT CORE1 DNA reverse strand, ...
Authors:Lv, X, Du, J.
Deposit date:2020-08-26
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into the multivalent binding of the Arabidopsis FLOWERING LOCUS T promoter by the CO-NF-Y master transcription factor complex.
Plant Cell, 33, 2021
7CVO
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BU of 7cvo by Molmil
crystal structure of Arabidopsis CO CCT domain in complex with NF-YB3/YC4 and FT CORE2 DNA
Descriptor: Chimera of Nuclear transcription factor Y subunit C-4 and Zinc finger protein CONSTANS, FT CORE2 DNA forward strand, FT CORE2 DNA reverse strand, ...
Authors:Lv, X, Du, J.
Deposit date:2020-08-26
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into the multivalent binding of the Arabidopsis FLOWERING LOCUS T promoter by the CO-NF-Y master transcription factor complex.
Plant Cell, 33, 2021
6HL8
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BU of 6hl8 by Molmil
Crystal Structure of the CsiD Glutarate Hydroxylase in complex with Glutarate
Descriptor: FE (II) ION, GLUTARIC ACID, Protein CsiD
Authors:Williams, R.M, Mayans, O, Hartig, J.S.
Deposit date:2018-09-10
Release date:2018-12-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate.
Nat Commun, 9, 2018
6VAJ
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BU of 6vaj by Molmil
Crystal Structure Analysis of human PIN1
Descriptor: 2-chloro-N-(2,2-dimethylpropyl)-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ...
Authors:Seo, H.-S, Dhe-Paganon, S.
Deposit date:2019-12-17
Release date:2020-12-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
Nat.Chem.Biol., 17, 2021
1F4J
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BU of 1f4j by Molmil
STRUCTURE OF TETRAGONAL CRYSTALS OF HUMAN ERYTHROCYTE CATALASE
Descriptor: CATALASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Safo, M.K, Musayev, F.N, Wu, S.H, Abraham, D.J, Ko, T.P.
Deposit date:2000-06-07
Release date:2000-06-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of tetragonal crystals of human erythrocyte catalase.
Acta Crystallogr.,Sect.D, 57, 2001
6W2D
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BU of 6w2d by Molmil
Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus
Descriptor: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ...
Authors:Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H.
Deposit date:2020-03-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus.
Nat Microbiol, 5, 2020
6W19
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BU of 6w19 by Molmil
Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus
Descriptor: Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
Authors:Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H.
Deposit date:2020-03-03
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus.
Nat Microbiol, 5, 2020
6W2E
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BU of 6w2e by Molmil
Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus
Descriptor: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ...
Authors:Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H.
Deposit date:2020-03-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus.
Nat Microbiol, 5, 2020
6KKI
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BU of 6kki by Molmil
Crystal structure of Drug:Proton Antiporter-1 (DHA1) Family SotB, in the inward-occluded conformation
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, Sugar efflux transporter, nonyl beta-D-glucopyranoside
Authors:Xiao, Q.J, Deng, D.
Deposit date:2019-07-25
Release date:2020-07-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.064 Å)
Cite:Visualizing the nonlinear changes of a drug-proton antiporter from inward-open to occluded state.
Biochem.Biophys.Res.Commun., 534, 2021
6HL9
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BU of 6hl9 by Molmil
Crystal Structure of the CsiD Glutarate Hydroxylase in complex with Succinate
Descriptor: FE (II) ION, Glutarate 2-hydroxylase, SUCCINIC ACID
Authors:Williams, R.M, Mayans, O, Hartig, J.S.
Deposit date:2018-09-10
Release date:2019-02-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate.
Nat Commun, 9, 2018
6KKL
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BU of 6kkl by Molmil
Crystal structure of Drug:Proton Antiporter-1 (DHA1) Family SotB, in the inward conformation (H115N mutant)
Descriptor: Sugar efflux transporter, nonyl beta-D-glucopyranoside
Authors:Xiao, Q.J, Sun, B, Zuo, Y.X, Guo, L, He, J.H, Deng, D.
Deposit date:2019-07-26
Release date:2020-07-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.654 Å)
Cite:Visualizing the nonlinear changes of a drug-proton antiporter from inward-open to occluded state.
Biochem.Biophys.Res.Commun., 534, 2021
6KKK
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BU of 6kkk by Molmil
Crystal structure of Drug:Proton Antiporter-1 (DHA1) Family SotB, in the inward open conformation (H115A mutant)
Descriptor: Sugar efflux transporter, nonyl beta-D-glucopyranoside
Authors:Xiao, Q.J, Deng, D.
Deposit date:2019-07-26
Release date:2020-07-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Visualizing the nonlinear changes of a drug-proton antiporter from inward-open to occluded state.
Biochem.Biophys.Res.Commun., 534, 2021
6KKJ
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BU of 6kkj by Molmil
Crystal structure of Drug:Proton Antiporter-1 (DHA1) Family SotB, in the inward open conformation
Descriptor: Sugar efflux transporter, nonyl beta-D-glucopyranoside
Authors:Xiao, Q.J, Deng, D.
Deposit date:2019-07-25
Release date:2020-07-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.385 Å)
Cite:Visualizing the nonlinear changes of a drug-proton antiporter from inward-open to occluded state.
Biochem.Biophys.Res.Commun., 534, 2021
6KSW
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BU of 6ksw by Molmil
Cryo-EM structure of the human concentrative nucleoside transporter CNT3
Descriptor: Solute carrier family 28 member 3
Authors:Zhou, Y.X, Liao, L.H, Li, J.L, Xiao, Q.J, Sun, L.F, Deng, D.
Deposit date:2019-08-26
Release date:2020-08-26
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the human concentrative nucleoside transporter CNT3.
Plos Biol., 18, 2020

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