7L6V
| |
7LZP
| LC/A-JPU-B9-JPU-A11-JPU-G11 | Descriptor: | Botulinum neurotoxin A light chain, JPU-A11, JPU-B9, ... | Authors: | Lam, K, Jin, R. | Deposit date: | 2021-03-10 | Release date: | 2021-12-22 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies. Plos Pathog., 18, 2022
|
|
7K84
| |
7K7Y
| |
6OQ7
| Structure of the GTD domain of Clostridium difficile toxin B in complex with VHH E3 | Descriptor: | E3, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Chen, P, Lam, K, Jin, R. | Deposit date: | 2019-04-25 | Release date: | 2019-07-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structure of the full-length Clostridium difficile toxin B. Nat.Struct.Mol.Biol., 26, 2019
|
|
7M1H
| |
7NA9
| Crystal structure of BoNT/B-LC-JSG-C1 | Descriptor: | 1,2-ETHANEDIOL, Botulinum neurotoxin type B, JSG-C1, ... | Authors: | Lam, K, Jin, R. | Deposit date: | 2021-06-20 | Release date: | 2021-12-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies. Plos Pathog., 18, 2022
|
|
5BQU
| Crystal structure of HA17-HA33-Lactulose | Descriptor: | HA-17, HA-33, beta-D-galactopyranose-(1-4)-beta-D-fructofuranose | Authors: | Lee, K, Lam, K, Jin, R. | Deposit date: | 2015-05-29 | Release date: | 2015-10-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics. Toxicon, 107, 2015
|
|
5BP5
| Crystal structure of HA17-HA33-IPT | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, HA-17, HA-33 | Authors: | Lee, K, Lam, K, Jin, R. | Deposit date: | 2015-05-27 | Release date: | 2015-09-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics. Toxicon, 107, 2015
|
|
7T5F
| |
7UIE
| Crystal structure of HcE-JLE-G6 | Descriptor: | Botulinum neurotoxin E heavy chain, JLE-G6 | Authors: | Jin, R, Lam, K. | Deposit date: | 2022-03-29 | Release date: | 2023-04-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2. Nat Commun, 14, 2023
|
|
5UAE
| Crystal structure of the coiled-coil domain from Listeria Innocua Phage Integrase (Trigonal Form) | Descriptor: | CITRATE ANION, Putative integrase | Authors: | Gupta, K, Sharp, R, Yuan, J.B, Van Duyne, G.D. | Deposit date: | 2016-12-19 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Coiled-coil interactions mediate serine integrase directionality. Nucleic Acids Res., 45, 2017
|
|
5UDO
| |
5U96
| |
3V65
| Crystal structure of agrin and LRP4 complex | Descriptor: | Agrin, CALCIUM ION, Low-density lipoprotein receptor-related protein 4 | Authors: | Zong, Y, Jin, R. | Deposit date: | 2011-12-18 | Release date: | 2012-04-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of agrin-LRP4-MuSK signaling. Genes Dev., 26, 2012
|
|
7UBX
| |
7UBY
| Structure of the GTD domain of Clostridium difficile toxin A in complex with VHH AH3 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glucosyltransferase TcdA, ... | Authors: | Chen, B, Rongsheng, J, Kay, P. | Deposit date: | 2022-03-15 | Release date: | 2022-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies. Front Immunol, 13, 2022
|
|
7UIB
| Crystal structure of BoNT/E receptor binding domain in complex with SV2, VHH, and sialic acid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-beta-neuraminic acid, ... | Authors: | Liu, Z, Jin, R, Chen, P. | Deposit date: | 2022-03-29 | Release date: | 2023-04-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2. Nat Commun, 14, 2023
|
|
7UIA
| Crystal structure of BoNT/E receptor binding domain in complex with SV2 and VHH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | Authors: | Liu, Z, Jin, R, Chen, P. | Deposit date: | 2022-03-28 | Release date: | 2023-04-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2. Nat Commun, 14, 2023
|
|
7S0Y
| Structures of TcdB in complex with Cdc42 | Descriptor: | Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Zheng, L, Rongsheng, J, Peng, C. | Deposit date: | 2021-08-31 | Release date: | 2021-09-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B. Sci Adv, 7, 2021
|
|
7S0Z
| Structures of TcdB in complex with R-Ras | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, AMMONIUM ION, ... | Authors: | Zheng, L, Rongsheng, J, Peng, C. | Deposit date: | 2021-08-31 | Release date: | 2021-09-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B. Sci Adv, 7, 2021
|
|
7U1Z
| Crystal structure of the DRBD and CROPs of TcdA | Descriptor: | SULFATE ION, Toxin A | Authors: | Baohua, C, Peng, C, Kay, P, Rongsheng, J. | Deposit date: | 2022-02-22 | Release date: | 2022-03-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | Structure and conformational dynamics of Clostridioides difficile toxin A. Life Sci Alliance, 5, 2022
|
|
7U2P
| Structure of TcdA GTD in complex with RhoA | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Glucosyltransferase TcdA, MAGNESIUM ION, ... | Authors: | Baohua, C, Zheng, L, Kay, P, Rongsheng, J. | Deposit date: | 2022-02-24 | Release date: | 2022-05-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.596 Å) | Cite: | Structure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition. Sci Rep, 12, 2022
|
|
5VOF
| DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban | Descriptor: | 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide, CALCIUM ION, Coagulation factor X, ... | Authors: | Krishnaswamy, S, Kumar, S. | Deposit date: | 2017-05-02 | Release date: | 2018-06-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass. Nat. Biotechnol., 36, 2018
|
|
5V38
| |