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4V2C
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BU of 4v2c by Molmil
mouse FLRT2 LRR domain in complex with rat Unc5D Ig1 domain
Descriptor: FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2, PROTEIN UNC5D
Authors:Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4UZQ
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BU of 4uzq by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH O-PALMITOLEOYL SERINE - CRYSTAL FORM IX - 1.5A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, PALMITOLEIC ACID, ...
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-07
Release date:2015-02-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
8S7C
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BU of 8s7c by Molmil
Ternary Complex of Cachd1, FZD5 and LRP6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-5, ...
Authors:Zhao, Y, Ren, J, Jones, E.Y.
Deposit date:2024-02-29
Release date:2024-04-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (4.7 Å)
Cite:Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain.
Science, 384, 2024
4WBH
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BU of 4wbh by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I APO - 2.2A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Protein notum homolog, ...
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-03
Release date:2015-02-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum deacylates Wnt proteins to suppress signalling activity
Nature, 519, 2015
4V2E
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BU of 4v2e by Molmil
FLRT3 LRR domain
Descriptor: FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 3
Authors:Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development.
Neuron, 84, 2014
4V2D
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BU of 4v2d by Molmil
FLRT2 LRR domain
Descriptor: FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2
Authors:Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2B
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BU of 4v2b by Molmil
rat Unc5D Ig domain 1
Descriptor: PROTEIN UNC5D
Authors:Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4UZ7
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BU of 4uz7 by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VI - 2.2A
Descriptor: CHLORIDE ION, PROTEIN NOTUM HOMOLOG
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
6FKM
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BU of 6fkm by Molmil
Drosophila Plexin A in complex with Semaphorin 1b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, Plexin A, ...
Authors:Rozbesky, D, Harlos, K, Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Structural basis of semaphorin-plexin cis interaction.
Embo J., 2020
6FKK
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BU of 6fkk by Molmil
Drosophila Semaphorin 1b, extracellular domains 1-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rozbesky, D, Harlos, K, Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning.
Nat Commun, 10, 2019
6FKN
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BU of 6fkn by Molmil
Drosophila Plexin A in complex with Semaphorin 1b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, Plexin A, ...
Authors:Rozbesky, D, Harlos, K, Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (4.801 Å)
Cite:Structural basis of semaphorin-plexin cis interaction.
Embo J., 2020
6GBI
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BU of 6gbi by Molmil
Wnt signalling
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ly6/PLAUR domain-containing protein 6, ...
Authors:Zhao, Y, Jones, E.Y.
Deposit date:2018-04-14
Release date:2018-08-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structure of the Wnt signaling enhancer LYPD6 and its interactions with the Wnt coreceptor LRP6.
FEBS Lett., 592, 2018
3SUA
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BU of 3sua by Molmil
Crystal structure of the intracellular domain of Plexin-B1 in complex with Rac1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-B1, ...
Authors:Bell, C.H, Aricescu, A.R, Jones, E.Y, Siebold, C.
Deposit date:2011-07-11
Release date:2011-09-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.39 Å)
Cite:A Dual Binding Mode for RhoGTPases in Plexin Signalling.
Plos Biol., 9, 2011
3SU8
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BU of 3su8 by Molmil
Crystal structure of a truncated intracellular domain of Plexin-B1 in complex with Rac1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-B1, ...
Authors:Bell, C.H, Aricescu, A.R, Jones, E.Y, Siebold, C.
Deposit date:2011-07-11
Release date:2011-09-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A Dual Binding Mode for RhoGTPases in Plexin Signalling.
Plos Biol., 9, 2011
1ZT4
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BU of 1zt4 by Molmil
The crystal structure of human CD1d with and without alpha-Galactosylceramide
Descriptor: Beta-2-microglobulin, N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE, T-cell surface glycoprotein CD1d
Authors:Koch, M, Stronge, V.S, Shepherd, D, Gadola, S.D, Mathew, B, Ritter, G, Fersht, A.R, Besra, G.S, Schmidt, R.R, Jones, E.Y, Cerundolo, V, Structural Proteomics in Europe (SPINE)
Deposit date:2005-05-26
Release date:2005-07-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of human CD1d with and without alpha-galactosylceramide
Nat.Immunol., 6, 2005
2BZY
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BU of 2bzy by Molmil
Homodimer of CrkL-SH3C domain
Descriptor: CRK-LIKE PROTEIN
Authors:Harkiolaki, M, Gilbert, R.J, Jones, E.Y, Feller, S.M.
Deposit date:2005-08-24
Release date:2006-09-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The C-Terminal SH3 Domain of Crkl as a Dynamic Dimerization Module Transiently Exposing a Nuclear Export Signal.
Structure, 14, 2006
1CCZ
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BU of 1ccz by Molmil
CRYSTAL STRUCTURE OF THE CD2-BINDING DOMAIN OF CD58 (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3) AT 1.8-A RESOLUTION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (CD58)
Authors:Ikemizu, S, Sparks, L.M, Van Der Merwe, P.A, Harlos, K, Stuart, D.I, Jones, E.Y, Davis, S.J.
Deposit date:1999-03-02
Release date:1999-04-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution.
Proc.Natl.Acad.Sci.USA, 96, 1999
1CE6
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BU of 1ce6 by Molmil
MHC CLASS I H-2DB COMPLEXED WITH A SENDAI VIRUS NUCLEOPROTEIN PEPTIDE
Descriptor: PROTEIN (HUMAN BETA-2 MICROGLOBULIN), PROTEIN (MHC CLASS I H-2DB HEAVY CHAIN), PROTEIN (SENDAI VIRUS NUCLEOPROTEIN), ...
Authors:Tormo, J, Jones, E.Y.
Deposit date:1999-03-17
Release date:1999-03-26
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity.
Immunity, 10, 1999
1D4V
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BU of 1d4v by Molmil
Crystal structure of trail-DR5 complex
Descriptor: DEATH RECEPTOR 5, TNF-RELATED APOPTOSIS INDUCING LIGAND
Authors:Mongkolsapaya, J, Grimes, J.M, Stuart, D.I, Jones, E.Y, Screaton, G.R.
Deposit date:1999-10-06
Release date:1999-11-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
Nat.Struct.Biol., 6, 1999
1E28
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BU of 1e28 by Molmil
Nonstandard peptide binding of HLA-B*5101 complexed with HIV immunodominant epitope KM2(TAFTIPSI)
Descriptor: BETA-2 MICROGLOBULIN LIGHT CHAIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HEAVY CHAIN, PEPTIDE
Authors:Maenaka, K, Maenaka, T, Tomiyama, H, Takiguchi, M, Stuart, D.I, Jones, E.Y.
Deposit date:2000-05-18
Release date:2000-09-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes.
J Immunol., 165, 2000
1E27
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BU of 1e27 by Molmil
Nonstandard peptide binding of HLA-B*5101 complexed with HIV immunodominant epitope KM1(LPPVVAKEI)
Descriptor: BETA-2 MICROGLOBULIN LIGHT CHAIN, HIV-1 PEPTIDE (LPPVVAKEI), HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HEAVY CHAIN
Authors:Maenaka, K, Maenaka, T, Tomiyama, H, Takiguchi, M, Stuart, D.I, Jones, E.Y.
Deposit date:2000-05-18
Release date:2000-09-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes.
J Immunol., 165, 2000
1B8M
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BU of 1b8m by Molmil
BRAIN DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-4
Descriptor: PROTEIN (BRAIN DERIVED NEUROTROPHIC FACTOR), PROTEIN (NEUROTROPHIN-4)
Authors:Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S.
Deposit date:1999-02-01
Release date:1999-02-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
1DR9
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BU of 1dr9 by Molmil
CRYSTAL STRUCTURE OF A SOLUBLE FORM OF B7-1 (CD80)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, T LYMPHOCYTE ACTIVATION ANTIGEN
Authors:Ikemizu, S, Jones, E.Y, Stuart, D.I, Davis, S.J.
Deposit date:2000-01-06
Release date:2000-01-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and dimerization of a soluble form of B7-1.
Immunity, 12, 2000
1MHE
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BU of 1mhe by Molmil
THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HLA-E, PEPTIDE (VMAPRTVLL), ...
Authors:O'Callaghan, C.A, Tormo, J, Willcox, B.E, Braud, V.B, Jakobsen, B.K, Stuart, D.I, Mcmichael, A.J, Bell, J.I, Jones, E.Y.
Deposit date:1998-08-24
Release date:1999-03-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Mol.Cell, 1, 1998
3GIV
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BU of 3giv by Molmil
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Descriptor: Beta-2-microglobulin, HIV-1 peptide, HLA class I histocompatibility antigen, ...
Authors:Stewart-Jones, G, Iversen, A.K.N, Jones, E.Y.
Deposit date:2009-03-06
Release date:2009-06-30
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Nat.Immunol., 10, 2009

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