8QCX
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8QCY
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8QCS
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8QD0
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8QCT
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8R8T
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6HRC
| Outward-facing PglK with ATPgammaS bound | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, WlaB protein | Authors: | Perez, C, Locher, K.P. | Deposit date: | 2018-09-26 | Release date: | 2019-03-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation. Structure, 27, 2019
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6HFB
| Outward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily. | Descriptor: | CESIUM ION, Uncharacterized protein | Authors: | Nonaka, T, Zakrzewska, S, Safarian, S, Michel, H. | Deposit date: | 2018-08-21 | Release date: | 2019-06-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.495 Å) | Cite: | Inward-facing conformation of a multidrug resistance MATE family transporter. Proc.Natl.Acad.Sci.USA, 116, 2019
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7NKZ
| Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution | Descriptor: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, HEME B/C, MENAQUINONE-9, ... | Authors: | Safarian, S, Wu, D, Krause, K.L, Michel, H. | Deposit date: | 2021-02-19 | Release date: | 2021-09-22 | Last modified: | 2021-09-29 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nat Commun, 12, 2021
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7N74
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7N73
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7N72
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7N70
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7N78
| Cryo-EM structure of ATP13A2 in the E2-Pi state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Sim, S.I, Park, E. | Deposit date: | 2021-06-09 | Release date: | 2021-11-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of polyamine transport by human ATP13A2 (PARK9). Mol.Cell, 81, 2021
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7N75
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7N76
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7N77
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7NB6
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7P7G
| Crystal structure of phosphorylated pT220 Casein Kinase I delta (CK1d), conformation 2 and 3 | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CITRIC ACID, ... | Authors: | Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-07-19 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes. Mol.Cell, 82, 2022
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7P7H
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7P7F
| Crystal structure of phosphorylated pT220 Casein Kinase I delta (CK1d), conformation 1 | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE, ADENOSINE MONOPHOSPHATE, ... | Authors: | Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-07-19 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes. Mol.Cell, 82, 2022
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7OT9
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8PEE
| ABCB1 L335C mutant (mABCB1) in the inward facing state bound to AAC | Descriptor: | (4S,11S,18S)-4-[[(2,4-dinitrophenyl)disulfanyl]methyl]-11,18-dimethyl-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, (4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, ATP-dependent translocase ABCB1, ... | Authors: | Parey, K, Januliene, D, Gewering, T, Moeller, A. | Deposit date: | 2023-06-13 | Release date: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Tracing the substrate translocation mechanism in P-glycoprotein. Elife, 12, 2024
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6YK8
| OTU-like deubiquitinase from Legionella -Lpg2529 | Descriptor: | PLATINUM (II) ION, Uncharacterized protein | Authors: | Shin, D, Dikic, I. | Deposit date: | 2020-04-05 | Release date: | 2021-02-10 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection. Elife, 9, 2020
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6Z71
| Structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | Descriptor: | Aq128 | Authors: | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | Deposit date: | 2020-05-29 | Release date: | 2021-12-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily. Proc.Natl.Acad.Sci.USA, 118, 2021
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