3WL5
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![BU of 3wl5 by Molmil](/molmil-images/mine/3wl5) | Crystal structure of pOPH S172C | Descriptor: | CITRIC ACID, Oxidized polyvinyl alcohol hydrolase | Authors: | Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chan, H.C, Ren, F.F, Jia, D.X, Wang, A.H.-J, Guo, R.T, Chen, J, Du, G.C. | Deposit date: | 2013-11-07 | Release date: | 2014-09-24 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural insights into enzymatic degradation of oxidized polyvinyl alcohol Chembiochem, 15, 2014
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3WSB
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![BU of 3wsb by Molmil](/molmil-images/mine/3wsb) | The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole | Descriptor: | Farnesyltransferase, putative, N-[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]-N'-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]ethane-1,2-diamine, ... | Authors: | Shang, N, Li, Q, Huang, C.H, Oldfield, E, Guo, R.T. | Deposit date: | 2014-03-05 | Release date: | 2015-04-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole To be Published
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3WCA
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![BU of 3wca by Molmil](/molmil-images/mine/3wca) | The complex structure of TcSQS with ligand, FSPP | Descriptor: | Farnesyltransferase, putative, MAGNESIUM ION, ... | Authors: | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Oldfield, E, Guo, R.T. | Deposit date: | 2013-05-26 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog., 10, 2014
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3WL8
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![BU of 3wl8 by Molmil](/molmil-images/mine/3wl8) | Crystal Structure of pOPH S172A with octanoic acid | Descriptor: | CITRIC ACID, OCTANOIC ACID (CAPRYLIC ACID), Oxidized polyvinyl alcohol hydrolase | Authors: | Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chan, H.C, Ren, F.F, Jia, D.X, Wang, A.H.-J, Guo, R.T, Chen, J, Du, G.C. | Deposit date: | 2013-11-08 | Release date: | 2014-09-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural insights into enzymatic degradation of oxidized polyvinyl alcohol Chembiochem, 15, 2014
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3WUB
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![BU of 3wub by Molmil](/molmil-images/mine/3wub) | The wild type crystal structure of b-1,4-Xylanase (XynAS9) from Streptomyces sp. 9 | Descriptor: | Endo-1,4-beta-xylanase A, ZINC ION | Authors: | Chen, C.C, Han, X, Lv, P, Ko, T.P, Peng, W, Huang, C.H, Zheng, Y, Gao, J, Yang, Y.Y, Guo, R.T. | Deposit date: | 2014-04-23 | Release date: | 2014-10-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural perspectives of an engineered beta-1,4-xylanase with enhanced thermostability. J.Biotechnol., 189C, 2014
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3WCH
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![BU of 3wch by Molmil](/molmil-images/mine/3wch) | The complex structure of HsSQS wtih ligand BPH1237 | Descriptor: | Squalene synthase, hydrogen [(1R)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-hydroxy-1-phosphonoethyl]phosphonate | Authors: | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | Deposit date: | 2013-05-27 | Release date: | 2014-06-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog., 10, 2014
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3WGZ
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![BU of 3wgz by Molmil](/molmil-images/mine/3wgz) | Crystal structure of meso-dapdh Q154L/T173I/R199M/P248S/H249N/N276S mutant with D-leucine of from Clostridium tetani E88 | Descriptor: | D-LEUCINE, Meso-diaminopimelate dehydrogenase | Authors: | Liu, W.D, Li, Z, Huang, C.H, Guo, R.T, Wu, Q.Q, Zhu, D.M. | Deposit date: | 2013-08-20 | Release date: | 2014-08-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of meso-dapdh Q154L/T173I/R199M/P248S/H249N/N276S mutant with D-leucine of from Clostridium tetani E88 to be published
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3WJK
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![BU of 3wjk by Molmil](/molmil-images/mine/3wjk) | Crystal structure of Octaprenyl Pyrophosphate synthase from Escherichia coli | Descriptor: | Octaprenyl diphosphate synthase | Authors: | Han, X, Chen, C.C, Kuo, C.J, Huang, C.H, Zheng, Y, Ko, T.P, Zhu, Z, Feng, X, Oldfield, E, Liang, P.H, Guo, R.T, Ma, Y.H. | Deposit date: | 2013-10-11 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms. Proteins, 83, 2015
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3WLF
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![BU of 3wlf by Molmil](/molmil-images/mine/3wlf) | Crystal structure of (R)-carbonyl reductase from Candida Parapsilosis in complex with (R)-1-phenyl-1,2-ethanediol | Descriptor: | (1R)-1-phenylethane-1,2-diol, (R)-specific carbonyl reductase, ZINC ION | Authors: | Wang, S.S, Nie, Y, Xu, Y, Zhang, R.Z, Huang, C.H, Chan, H.C, Guo, R.T, Xiao, R. | Deposit date: | 2013-11-09 | Release date: | 2014-07-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Unconserved substrate-binding sites direct the stereoselectivity of medium-chain alcohol dehydrogenase Chem.Commun.(Camb.), 50, 2014
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3WCD
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![BU of 3wcd by Molmil](/molmil-images/mine/3wcd) | The complex structure of HsSQS wtih ligand, WC-9 | Descriptor: | 2-(4-phenoxyphenoxy)ethyl thiocyanate, Squalene synthase | Authors: | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | Deposit date: | 2013-05-27 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog., 10, 2014
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3WDH
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![BU of 3wdh by Molmil](/molmil-images/mine/3wdh) | Crystal structure of Pullulanase from Anoxybacillus sp. LM18-11 | Descriptor: | CALCIUM ION, Type I pullulanase | Authors: | Xu, J, Ren, F, Huang, C.H, Zheng, Y, Zhen, J, Ko, T.P, Chen, C.C, Chan, H.C, Guo, R.T, Ma, Y, Song, H. | Deposit date: | 2013-06-18 | Release date: | 2014-06-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Cloning, Expression, Functional and Structural Studies of Pullulanase from Anoxybacillus sp. LM18-11 To be Published
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3WLA
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![BU of 3wla by Molmil](/molmil-images/mine/3wla) | Crystal Structure of sOPH Native | Descriptor: | Oxidized polyvinyl alcohol hydrolase, SULFATE ION | Authors: | Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chan, H.C, Ren, F.F, Jia, D.X, Wang, A.H.-J, Guo, R.T, Chen, J, Du, G.C. | Deposit date: | 2013-11-08 | Release date: | 2014-09-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into enzymatic degradation of oxidized polyvinyl alcohol Chembiochem, 15, 2014
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3WUG
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![BU of 3wug by Molmil](/molmil-images/mine/3wug) | The mutant crystal structure of b-1,4-Xylanase (XynAS9_V43P/G44E) with xylobiose from Streptomyces sp. 9 | Descriptor: | Endo-1,4-beta-xylanase A, ZINC ION, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | Authors: | Chen, C.C, Han, X, Lv, P, Ko, T.P, Peng, W, Huang, C.H, Zheng, Y, Gao, J, Yang, Y.Y, Guo, R.T. | Deposit date: | 2014-04-23 | Release date: | 2014-10-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structural perspectives of an engineered beta-1,4-xylanase with enhanced thermostability. J.Biotechnol., 189C, 2014
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3WQM
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![BU of 3wqm by Molmil](/molmil-images/mine/3wqm) | Crystal structure of Rv3378c with inhibitor BPH-629 | Descriptor: | Diterpene synthase, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T. | Deposit date: | 2014-01-28 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136, 2014
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3WWE
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![BU of 3wwe by Molmil](/molmil-images/mine/3wwe) | The complex of pOPH with PEG | Descriptor: | 2-(2-ETHOXYETHOXY)ETHANOL, Oxidized polyvinyl alcohol hydrolase | Authors: | Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chen, J, Guo, R.T, Du, G.C. | Deposit date: | 2014-06-17 | Release date: | 2015-04-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Roles of tryptophan residue and disulfide bond in the variable lid region of oxidized polyvinyl alcohol hydrolase Biochem.Biophys.Res.Commun., 452, 2014
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3WCE
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![BU of 3wce by Molmil](/molmil-images/mine/3wce) | The complex structure of TcSQS with ligand, ER119884 | Descriptor: | (3R)-3-{[2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl]ethynyl}-1-azabicyclo[2.2.2]octan-3-ol, Farnesyltransferase, putative | Authors: | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | Deposit date: | 2013-05-27 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog., 10, 2014
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3WCM
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![BU of 3wcm by Molmil](/molmil-images/mine/3wcm) | The complex structure of HsSQS wtih ligand, ER119884 | Descriptor: | (3R)-3-{[2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl]ethynyl}-1-azabicyclo[2.2.2]octan-3-ol, Squalene synthase | Authors: | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | Deposit date: | 2013-05-28 | Release date: | 2014-06-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog., 10, 2014
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3WC9
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![BU of 3wc9 by Molmil](/molmil-images/mine/3wc9) | The complex structure of HsSQS wtih ligand, FSPP | Descriptor: | S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Squalene synthase | Authors: | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | Deposit date: | 2013-05-26 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog., 10, 2014
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3WP6
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![BU of 3wp6 by Molmil](/molmil-images/mine/3wp6) | The complex structure of CDBFV E109A with xylotriose | Descriptor: | CDBFV, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | Authors: | Cheng, Y.S, Chen, C.C, Huang, C.H, Huang, T.Y, Ko, T.P, Huang, J.W, Wu, T.H, Liu, J.R, Guo, R.T. | Deposit date: | 2014-01-09 | Release date: | 2014-03-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structural analysis of a glycoside hydrolase family 11 xylanase from Neocallimastix patriciarum: insights into the molecular basis of a thermophilic enzyme. J.Biol.Chem., 289, 2014
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3WP4
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![BU of 3wp4 by Molmil](/molmil-images/mine/3wp4) | The crystal structure of native CDBFV from Neocallimastix patriciarum | Descriptor: | CDBFV, SULFATE ION | Authors: | Cheng, Y.S, Chen, C.C, Huang, C.H, Huang, T.Y, Ko, T.P, Huang, J.W, Wu, T.H, Liu, J.R, Guo, R.T. | Deposit date: | 2014-01-09 | Release date: | 2014-03-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Structural analysis of a glycoside hydrolase family 11 xylanase from Neocallimastix patriciarum: insights into the molecular basis of a thermophilic enzyme. J.Biol.Chem., 289, 2014
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4LE4
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![BU of 4le4 by Molmil](/molmil-images/mine/4le4) | Crystal structure of PaGluc131A with cellotriose | Descriptor: | Beta-glucanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Jiang, T, Chan, H.C, Huang, C.H, Ko, T.P, Huang, T.Y, Liu, J.R, Guo, R.T. | Deposit date: | 2013-06-25 | Release date: | 2013-09-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of a GH131 beta-Glucanase Catalytic Domain from Podospora anserina in Complex with Cellotriose To be Published
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4LE3
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![BU of 4le3 by Molmil](/molmil-images/mine/4le3) | Crystal structure of a GH131 beta-glucanase catalytic domain from Podospora anserina | Descriptor: | Beta-glucanase | Authors: | Jiang, T, Chan, H.C, Huang, C.H, Ko, T.P, Huang, T.Y, Liu, J.R, Guo, R.T. | Deposit date: | 2013-06-25 | Release date: | 2013-09-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of a GH131 beta-Glucanase Catalytic Domain from Podospora anserina in Complex with Cellotriose To be Published
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3WZL
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![BU of 3wzl by Molmil](/molmil-images/mine/3wzl) | ZEN lactonase | Descriptor: | Zearalenone hydrolase | Authors: | Ko, T.P, Huang, C.H, Liu, J.R, Guo, R.T. | Deposit date: | 2014-10-01 | Release date: | 2014-11-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure and substrate-binding mode of the mycoestrogen-detoxifying lactonase ZHD from Clonostachys rosea RSC ADV, 4, 2014
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3WZM
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![BU of 3wzm by Molmil](/molmil-images/mine/3wzm) | ZEN lactonase mutant complex | Descriptor: | (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, Zearalenone hydrolase | Authors: | Ko, T.P, Huang, C.H, Liu, J.R, Guo, R.T. | Deposit date: | 2014-10-01 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Crystal structure and substrate-binding mode of the mycoestrogen-detoxifying lactonase ZHD from Clonostachys rosea RSC ADV, 4, 2014
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4NES
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![BU of 4nes by Molmil](/molmil-images/mine/4nes) | Crystal structure of Methanocaldococcus jannaschii UDP-GlcNAc 2-epimerase in complex with UDP-GlcNAc and UDP | Descriptor: | UDP-N-acetylglucosamine 2-epimerase, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Chen, S.C, Yang, C.S, Huang, C.H, Chen, Y. | Deposit date: | 2013-10-30 | Release date: | 2014-04-23 | Last modified: | 2015-06-17 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc. Proteins, 82, 2014
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