1Y2Y
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![BU of 1y2y by Molmil](/molmil-images/mine/1y2y) | Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy | Descriptor: | Ribosome biogenesis protein Nop10 | Authors: | Khanna, M, Wu, H, Johansson, C, Caizergues-Ferrer, M, Feigon, J. | Deposit date: | 2004-11-23 | Release date: | 2005-12-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA RNA, 12, 2006
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7L0P
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![BU of 7l0p by Molmil](/molmil-images/mine/7l0p) | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | Deposit date: | 2020-12-12 | Release date: | 2021-01-06 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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7L0S
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![BU of 7l0s by Molmil](/molmil-images/mine/7l0s) | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, with AHD | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | Deposit date: | 2020-12-12 | Release date: | 2021-01-06 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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7L0R
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![BU of 7l0r by Molmil](/molmil-images/mine/7l0r) | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | Deposit date: | 2020-12-12 | Release date: | 2021-01-06 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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7CSP
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![BU of 7csp by Molmil](/molmil-images/mine/7csp) | Structure of Ephexin4 IDPSH | Descriptor: | Rho guanine nucleotide exchange factor 16 | Authors: | Zhang, M, Lin, L, Wang, C, Zhu, J. | Deposit date: | 2020-08-15 | Release date: | 2021-02-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Proc.Natl.Acad.Sci.USA, 118, 2021
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7CSR
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![BU of 7csr by Molmil](/molmil-images/mine/7csr) | Structure of Ephexin4 R676L | Descriptor: | Rho guanine nucleotide exchange factor 16 | Authors: | Zhang, M, Lin, L, Wang, C, Zhu, J. | Deposit date: | 2020-08-17 | Release date: | 2021-02-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Proc.Natl.Acad.Sci.USA, 118, 2021
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7CSO
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![BU of 7cso by Molmil](/molmil-images/mine/7cso) | Structure of Ephexin4 DH-PH-SH3 | Descriptor: | Rho guanine nucleotide exchange factor 16, SULFATE ION | Authors: | Zhang, M, Lin, L, Wang, C, Zhu, J. | Deposit date: | 2020-08-15 | Release date: | 2021-02-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Proc.Natl.Acad.Sci.USA, 118, 2021
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7L0Q
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![BU of 7l0q by Molmil](/molmil-images/mine/7l0q) | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, with AHD | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | Deposit date: | 2020-12-12 | Release date: | 2021-01-06 | Last modified: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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4J9Z
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![BU of 4j9z by Molmil](/molmil-images/mine/4j9z) | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and NS309 | Descriptor: | (3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin, ... | Authors: | Zhang, M, Pascal, J.M, Zhang, J.-F. | Deposit date: | 2013-02-17 | Release date: | 2013-03-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca2+-sensing and SK channel activation. Proc.Natl.Acad.Sci.USA, 110, 2013
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4J9Y
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![BU of 4j9y by Molmil](/molmil-images/mine/4j9y) | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant | Descriptor: | CALCIUM ION, Calmodulin, GLYCEROL, ... | Authors: | Zhang, M, Pascal, J.M, Zhang, J.-F. | Deposit date: | 2013-02-17 | Release date: | 2013-03-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca2+-sensing and SK channel activation. Proc.Natl.Acad.Sci.USA, 110, 2013
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1T3B
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![BU of 1t3b by Molmil](/molmil-images/mine/1t3b) | X-ray Structure of DsbC from Haemophilus influenzae | Descriptor: | Thiol:disulfide interchange protein dsbC | Authors: | Zhang, M, Monzingo, A.F, Segatori, L, Georgiou, G, Robertus, J.D. | Deposit date: | 2004-04-26 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of DsbC from Haemophilus influenzae. Acta Crystallogr.,Sect.D, 60, 2004
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3NON
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![BU of 3non by Molmil](/molmil-images/mine/3non) | Crystal Structure of Isocyanide Hydratase from Pseudomonas fluorescens | Descriptor: | 1,2-ETHANEDIOL, Isocyanide hydratase | Authors: | Lakshminarasimhan, M, Madzelan, P, Nan, R, Milkovic, N.M, Wilson, M.A. | Deposit date: | 2010-06-25 | Release date: | 2010-07-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratase. J.Biol.Chem., 285, 2010
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3NOV
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![BU of 3nov by Molmil](/molmil-images/mine/3nov) | Crystal Structure of D17E Isocyanide Hydratase from Pseudomonas fluorescens | Descriptor: | ACETATE ION, ThiJ/PfpI family protein | Authors: | Lakshminarasimhan, M, Madzelan, P, Nan, R, Milkovic, N.M, Wilson, M.A. | Deposit date: | 2010-06-25 | Release date: | 2010-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratase. J.Biol.Chem., 285, 2010
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3NOO
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![BU of 3noo by Molmil](/molmil-images/mine/3noo) | Crystal Structure of C101A Isocyanide Hydratase from Pseudomonas fluorescens | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ThiJ/PfpI family protein | Authors: | Lakshminarasimhan, M, Madzelan, P, Nan, R, Milkovic, N.M, Wilson, M.A. | Deposit date: | 2010-06-25 | Release date: | 2010-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratase. J.Biol.Chem., 285, 2010
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3B38
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![BU of 3b38 by Molmil](/molmil-images/mine/3b38) | Structure of A104V DJ-1 | Descriptor: | 1,2-ETHANEDIOL, Protein DJ-1 | Authors: | Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. | Deposit date: | 2007-10-19 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1. Biochemistry, 47, 2008
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4KKY
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![BU of 4kky by Molmil](/molmil-images/mine/4kky) | |
2RK4
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![BU of 2rk4 by Molmil](/molmil-images/mine/2rk4) | Structure of M26I DJ-1 | Descriptor: | Protein DJ-1 | Authors: | Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. | Deposit date: | 2007-10-16 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1. Biochemistry, 47, 2008
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3B36
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![BU of 3b36 by Molmil](/molmil-images/mine/3b36) | Structure of M26L DJ-1 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Protein DJ-1 | Authors: | Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. | Deposit date: | 2007-10-19 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1. Biochemistry, 47, 2008
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1W7W
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![BU of 1w7w by Molmil](/molmil-images/mine/1w7w) | |
2RK3
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![BU of 2rk3 by Molmil](/molmil-images/mine/2rk3) | Structure of A104T DJ-1 | Descriptor: | Protein DJ-1 | Authors: | Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. | Deposit date: | 2007-10-16 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1. Biochemistry, 47, 2008
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2RK6
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![BU of 2rk6 by Molmil](/molmil-images/mine/2rk6) | Structure of E163K DJ-1 | Descriptor: | Protein DJ-1 | Authors: | Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. | Deposit date: | 2007-10-16 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1. Biochemistry, 47, 2008
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3B3A
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![BU of 3b3a by Molmil](/molmil-images/mine/3b3a) | Structure of E163K/R145E DJ-1 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Protein DJ-1 | Authors: | Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. | Deposit date: | 2007-10-19 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1. Biochemistry, 47, 2008
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3NOQ
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![BU of 3noq by Molmil](/molmil-images/mine/3noq) | Crystal Structure of C101S Isocyanide Hydratase from Pseudomonas fluorescens | Descriptor: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ThiJ/PfpI family protein | Authors: | Lakshminarasimhan, M, Madzelan, P, Nan, R, Milkovic, N.M, Wilson, M.A. | Deposit date: | 2010-06-25 | Release date: | 2010-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratase. J.Biol.Chem., 285, 2010
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3NOR
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![BU of 3nor by Molmil](/molmil-images/mine/3nor) | Crystal Structure of T102S Isocyanide Hydratase from Pseudomonas fluorescens | Descriptor: | CITRIC ACID, ThiJ/PfpI family protein | Authors: | Lakshminarasimhan, M, Madzelan, P, Nan, R, Milkovic, N.M, Wilson, M.A. | Deposit date: | 2010-06-25 | Release date: | 2010-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratase. J.Biol.Chem., 285, 2010
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4QNH
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![BU of 4qnh by Molmil](/molmil-images/mine/4qnh) | Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-a | Descriptor: | CALCIUM ION, Calmodulin, SULFATE ION, ... | Authors: | Zhang, M, Pascal, J.M, Logothetis, D.E, Zhang, J.F. | Deposit date: | 2014-06-17 | Release date: | 2014-08-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex. Nat.Chem.Biol., 10, 2014
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