4GAW
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![BU of 4gaw by Molmil](/molmil-images/mine/4gaw) | Crystal structure of active human granzyme H | Descriptor: | CHLORIDE ION, Granzyme H, SULFATE ION | Authors: | Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. | Deposit date: | 2012-07-25 | Release date: | 2013-01-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
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3TKQ
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![BU of 3tkq by Molmil](/molmil-images/mine/3tkq) | Crystal structure of full-length human peroxiredoxin 4 with mixed conformation | Descriptor: | Peroxiredoxin-4 | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | Deposit date: | 2011-08-28 | Release date: | 2011-10-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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3TK9
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![BU of 3tk9 by Molmil](/molmil-images/mine/3tk9) | Crystal structure of human granzyme H | Descriptor: | Granzyme H, SULFATE ION | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | Deposit date: | 2011-08-25 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif J.Immunol., 188, 2012
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3TJV
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![BU of 3tjv by Molmil](/molmil-images/mine/3tjv) | Crystal structure of human granzyme H with a peptidyl substrate | Descriptor: | Granzyme H, PTSYAGDDSG, SULFATE ION | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | Deposit date: | 2011-08-25 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif J.Immunol., 188, 2012
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4HND
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![BU of 4hnd by Molmil](/molmil-images/mine/4hnd) | Crystal structure of the catalytic domain of Selenomethionine substituted human PI4KIIalpha in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 4-kinase type 2-alpha | Authors: | Zhou, Q, Zhai, Y, Zhang, K, Chen, C, Sun, F. | Deposit date: | 2012-10-19 | Release date: | 2014-04-09 | Last modified: | 2016-12-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Molecular insights into the membrane-associated phosphatidylinositol 4-kinase II alpha. Nat Commun, 5, 2014
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4HQM
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![BU of 4hqm by Molmil](/molmil-images/mine/4hqm) | The crystal structure of QsrR-menadione complex | Descriptor: | 2-methylnaphthalene-1,4-diol, QsrR protein | Authors: | Ji, Q, Zhang, L, Jones, M.B, Sun, F, Deng, X, Liang, H, Brugarolas, P, Gao, N, Peterson, S.N, Lan, L, Bae, T, He, C. | Deposit date: | 2012-10-25 | Release date: | 2013-03-06 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Proc.Natl.Acad.Sci.USA, 110, 2013
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3TKR
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![BU of 3tkr by Molmil](/molmil-images/mine/3tkr) | Crystal structure of full-length human peroxiredoxin 4 with T118E mutation | Descriptor: | Peroxiredoxin-4 | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | Deposit date: | 2011-08-28 | Release date: | 2011-10-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
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4HNE
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![BU of 4hne by Molmil](/molmil-images/mine/4hne) | Crystal structure of the catalytic domain of human type II alpha Phosphatidylinositol 4-kinase (PI4KIIalpha) in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 4-kinase type 2-alpha | Authors: | Zhou, Q, Zhai, Y, Zhang, K, Chen, C, Sun, F. | Deposit date: | 2012-10-19 | Release date: | 2014-04-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Molecular insights into the membrane-associated phosphatidylinositol 4-kinase II alpha. Nat Commun, 5, 2014
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7VOP
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![BU of 7vop by Molmil](/molmil-images/mine/7vop) | Cryo-EM structure of Xenopus laevis nuclear pore complex cytoplasmic ring subunit | Descriptor: | GATOR complex protein SEC13, IL4I1 protein, MGC154553 protein, ... | Authors: | Tai, L, Zhu, Y, Sun, F. | Deposit date: | 2021-10-14 | Release date: | 2022-02-02 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | 8 angstrom structure of the outer rings of the Xenopus laevis nuclear pore complex obtained by cryo-EM and AI. Protein Cell, 13, 2022
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7VCI
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![BU of 7vci by Molmil](/molmil-images/mine/7vci) | Structure of Xenopus laevis NPC nuclear ring asymmetric unit | Descriptor: | GATOR complex protein SEC13, MGC154553 protein, MGC83295 protein, ... | Authors: | Tai, L, Zhu, Y, Sun, F. | Deposit date: | 2021-09-03 | Release date: | 2022-02-02 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (8.1 Å) | Cite: | 8 angstrom structure of the outer rings of the Xenopus laevis nuclear pore complex obtained by cryo-EM and AI. Protein Cell, 13, 2022
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7WGZ
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![BU of 7wgz by Molmil](/molmil-images/mine/7wgz) | SARS-CoV-2 spike glycoprotein trimer in open state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhu, Y, Tai, L, Yin, G, Sun, F. | Deposit date: | 2021-12-29 | Release date: | 2023-01-04 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies Cell Discov, 8, 2022
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7WGX
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![BU of 7wgx by Molmil](/molmil-images/mine/7wgx) | SARS-CoV-2 spike glycoprotein trimer in closed state after treatment with Cathepsin L | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ... | Authors: | Zhu, Y, Tai, L, Yin, G, Sun, F. | Deposit date: | 2021-12-29 | Release date: | 2023-01-04 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies Cell Discov, 8, 2022
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7WGY
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![BU of 7wgy by Molmil](/molmil-images/mine/7wgy) | SARS-CoV-2 spike glycoprotein trimer in Intermediate state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhu, Y, Tai, L, Yin, G, Sun, F. | Deposit date: | 2021-12-29 | Release date: | 2023-01-04 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies Cell Discov, 8, 2022
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7WGV
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![BU of 7wgv by Molmil](/molmil-images/mine/7wgv) | SARS-CoV-2 spike glycoprotein trimer in closed state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ... | Authors: | Zhu, Y, Tai, L, Yin, G, Sun, F. | Deposit date: | 2021-12-29 | Release date: | 2023-01-04 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies Cell Discov, 8, 2022
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7Y37
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![BU of 7y37 by Molmil](/molmil-images/mine/7y37) | |
8H77
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![BU of 8h77 by Molmil](/molmil-images/mine/8h77) | Hsp90-AhR-p23-XAP2 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | Deposit date: | 2022-10-19 | Release date: | 2023-01-04 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
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7XRD
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![BU of 7xrd by Molmil](/molmil-images/mine/7xrd) | |
6KYL
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![BU of 6kyl by Molmil](/molmil-images/mine/6kyl) | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 in Complex with (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, Mitochondrial distribution and morphology protein 35, Protein UPS1, ... | Authors: | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | Deposit date: | 2019-09-19 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1. Commun Biol, 3, 2020
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6LOD
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![BU of 6lod by Molmil](/molmil-images/mine/6lod) | Cryo-EM structure of the air-oxidized photosynthetic alternative complex III from Roseiflexus castenholzii | Descriptor: | Cytochrome c domain-containing protein, FE3-S4 CLUSTER, Fe-S-cluster-containing hydrogenase components 1-like protein, ... | Authors: | Shi, Y, Xin, Y.Y, Wang, C, Blankenship, R.E, Sun, F, Xu, X.L. | Deposit date: | 2020-01-05 | Release date: | 2020-11-04 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of the air-oxidized and dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii . Sci Adv, 6, 2020
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6LML
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![BU of 6lml by Molmil](/molmil-images/mine/6lml) | Cryo-EM structure of the human glucagon receptor in complex with Gi1 | Descriptor: | Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Qiao, A, Han, S, Li, X, Sun, F, Zhao, Q, Wu, B. | Deposit date: | 2019-12-26 | Release date: | 2020-04-01 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367, 2020
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6LVN
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![BU of 6lvn by Molmil](/molmil-images/mine/6lvn) | Structure of the 2019-nCoV HR2 Domain | Descriptor: | Spike protein S2' | Authors: | Zhu, Y, Sun, F. | Deposit date: | 2020-02-04 | Release date: | 2020-02-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Crystal structure of HR2 domain of 2019-nCoV S2 subunit To Be Published
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6M52
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![BU of 6m52 by Molmil](/molmil-images/mine/6m52) | Human apo ferritin frozen on TEM grid with amorphous carbon supporting film | Descriptor: | FE (II) ION, Ferritin heavy chain | Authors: | Huang, X, Zhang, L, Wen, Z, Chen, H, Li, S, Ji, G, Yin, C, Sun, F. | Deposit date: | 2020-03-09 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation. Prog.Biophys.Mol.Biol., 156, 2020
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7Y04
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![BU of 7y04 by Molmil](/molmil-images/mine/7y04) | Hsp90-AhR-p23 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Aryl hydrocarbon receptor, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | Deposit date: | 2022-06-03 | Release date: | 2023-01-04 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
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8I7R
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![BU of 8i7r by Molmil](/molmil-images/mine/8i7r) | In situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeat | Descriptor: | Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | Authors: | Zhu, Y, Yin, G.L, Tai, L.H, Sun, F. | Deposit date: | 2023-02-02 | Release date: | 2023-10-11 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | In-cell structural insight into the stability of sperm microtubule doublet. Cell Discov, 9, 2023
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8I7O
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![BU of 8i7o by Molmil](/molmil-images/mine/8i7o) | In situ structure of axonemal doublet microtubules in mouse sperm with 16-nm repeat | Descriptor: | Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 20, Cilia- and flagella-associated protein 276, ... | Authors: | Zhu, Y, Yin, G.L, Tai, L.H, Sun, F. | Deposit date: | 2023-02-01 | Release date: | 2023-10-11 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | In-cell structural insight into the stability of sperm microtubule doublet. Cell Discov, 9, 2023
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