6OI3
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![BU of 6oi3 by Molmil](/molmil-images/mine/6oi3) | Crystal structure of human WDR5 in complex with monomethyl H3R2 peptide | Descriptor: | GLYCEROL, Monomethyl H3R2 peptide, SULFATE ION, ... | Authors: | Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D. | Deposit date: | 2019-04-08 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5. Biochemistry, 59, 2020
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6OI1
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![BU of 6oi1 by Molmil](/molmil-images/mine/6oi1) | Crystal structure of human WDR5 in complex with monomethyl L-arginine | Descriptor: | (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, GLYCEROL, SULFATE ION, ... | Authors: | Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D. | Deposit date: | 2019-04-08 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5. Biochemistry, 59, 2020
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1EZR
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![BU of 1ezr by Molmil](/molmil-images/mine/1ezr) | CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR | Descriptor: | CALCIUM ION, NUCLEOSIDE HYDROLASE | Authors: | Shi, W, Schramm, V.L, Almo, S.C. | Deposit date: | 2000-05-11 | Release date: | 2000-05-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure. J.Biol.Chem., 274, 1999
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1G2Q
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1G2P
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![BU of 1g2p by Molmil](/molmil-images/mine/1g2p) | CRYSTAL STRUCTURE OF ADENINE PHOSPHORIBOSYLTRANSFERASE | Descriptor: | ADENINE PHOSPHORIBOSYLTRANSFERASE 1, SULFATE ION | Authors: | Shi, W, Tanaka, K.S.E, Almo, S.C, Schramm, V.L. | Deposit date: | 2000-10-20 | Release date: | 2001-12-05 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae. Biochemistry, 40, 2001
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1G2O
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![BU of 1g2o by Molmil](/molmil-images/mine/1g2o) | CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A TRANSITION-STATE INHIBITOR | Descriptor: | 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, PURINE NUCLEOSIDE PHOSPHORYLASE | Authors: | Shi, W, Basso, L.A, Tyler, P.C, Furneaux, R.H, Blanchard, J.S, Almo, S.C, Schramm, V.L. | Deposit date: | 2000-10-20 | Release date: | 2001-08-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces. Biochemistry, 40, 2001
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3LVS
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![BU of 3lvs by Molmil](/molmil-images/mine/3lvs) | Crystal structure of farnesyl diphosphate synthase from rhodobacter capsulatus sb1003 | Descriptor: | FARNESYL DIPHOSPHATE SYNTHASE, GLYCEROL, PHOSPHATE ION | Authors: | Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-02-22 | Release date: | 2010-03-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013
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3LTE
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![BU of 3lte by Molmil](/molmil-images/mine/3lte) | CRYSTAL STRUCTURE OF RESPONSE REGULATOR (SIGNAL RECEIVER DOMAIN) FROM Bermanella marisrubri | Descriptor: | GLYCEROL, PHOSPHATE ION, Response regulator | Authors: | Patskovsky, Y, Toro, R, Gilmore, M, Miller, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-02-15 | Release date: | 2010-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CRYSTAL STRUCTURE OF RESPONSE REGULATOR SIGNAL RECEIVER DOMAIN FROM Bermanella marisrubri RED65 To be Published
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4JYK
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![BU of 4jyk by Molmil](/molmil-images/mine/4jyk) | Structure of E. coli Transcriptional Regulator RutR with bound uracil | Descriptor: | HTH-type transcriptional regulator RutR, SULFATE ION, URACIL | Authors: | Cooper, D.R, Knapik, A.A, Petkowski, J.J, Porebski, P.J, Osinski, T, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-03-29 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of E. coli Transcriptional Regulator RutR with bound uracil To be Published
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4JYJ
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![BU of 4jyj by Molmil](/molmil-images/mine/4jyj) | Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444 | Descriptor: | Enoyl-CoA hydratase/isomerase, UNKNOWN LIGAND | Authors: | Cooper, D.R, Porebski, P.J, Domagalski, M.J, Ahmed, M, Stead, M, Hillerich, B, Seidel, R, Zimmerman, M, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-03-29 | Release date: | 2013-05-29 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444 To be Published
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3LOC
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![BU of 3loc by Molmil](/molmil-images/mine/3loc) | Crystal structure of putative transcriptional regulator ycdc | Descriptor: | HTH-type transcriptional regulator rutR, URACIL | Authors: | Patskovsky, Y.V, Knapik, A.A, Mennella, V, Burley, S.K, Minor, W, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-02-03 | Release date: | 2010-03-16 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Hypothetical Transcriptional Regulator Ycdc from Escherichia Coli To be Published
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3LXZ
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4K1W
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![BU of 4k1w by Molmil](/molmil-images/mine/4k1w) | Crystal structure of the A314P mutant of mannonate dehydratase from novosphingobium aromaticivorans complexed with mg and d-mannonate | Descriptor: | 1,3-PROPANDIOL, CARBON DIOXIDE, CARBONATE ION, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Wichelecki, D, Gerlt, J.A, Almo, S.C. | Deposit date: | 2013-04-06 | Release date: | 2014-04-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.646 Å) | Cite: | Crystal structure of the A314P mutant of mannonate
dehydratase from novosphingobium aromaticivorans complexed with mg
and d-mannonate To be Published
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4K8L
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![BU of 4k8l by Molmil](/molmil-images/mine/4k8l) | Crystal structure of a putative 4-hydroxyproline epimerase/3-hydroxyproline dehydratse from the soil bacterium ochrobacterium anthropi, target efi-506495, disordered loops | Descriptor: | Proline racemase | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Washington, E, Scott Glen, A, Chowdhury, S, Evens, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-04-18 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a putative 4-hydroxyproline epimerase/3-hydroxyproline dehydratse from the soil bacterium ochrobacterium anthropi, target efi-506495, disordered loops To be Published
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4K9C
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![BU of 4k9c by Molmil](/molmil-images/mine/4k9c) | CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE and 4-METHYL-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-7-CARBOXYLIC ACID | Descriptor: | 4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid, ADENOSINE, DIMETHYL SULFOXIDE, ... | Authors: | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-04-19 | Release date: | 2013-05-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE and 4-METHYL-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-7-CARBOXYLIC ACID To be Published
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3LSB
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![BU of 3lsb by Molmil](/molmil-images/mine/3lsb) | Crystal structure of the mutant E241Q of atrazine chlorohydrolase TrzN from Arthrobacter aurescens TC1 complexed with zinc and ametrin | Descriptor: | N-ethyl-N'-(1-methylethyl)-6-(methylsulfanyl)-1,3,5-triazine-2,4-diamine, Triazine hydrolase, ZINC ION | Authors: | Fedorov, A.A, Fedorov, E.V, Seffernick, J, Wackett, L.P, Almo, S.C. | Deposit date: | 2010-02-12 | Release date: | 2010-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.932 Å) | Cite: | Crystal structure of the mutant E241Q of atrazine chlorohydrolase TrzN
from Arthrobacter aurescens TC1 complexed with zinc and Ametryn To be Published
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4KAL
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![BU of 4kal by Molmil](/molmil-images/mine/4kal) | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinoline-3-carboxylic acid | Descriptor: | ADENOSINE, DIMETHYL SULFOXIDE, POTASSIUM ION, ... | Authors: | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-04-22 | Release date: | 2013-05-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinoline-3-carboxylic acid To be Published
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3LV5
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![BU of 3lv5 by Molmil](/molmil-images/mine/3lv5) | Crystal structure of the mutant I199E of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase | Authors: | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | Deposit date: | 2010-02-19 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.444 Å) | Cite: | Conformational changes in orotidine 5'-monophosphate decarboxylase: "remote" residues that stabilize the active conformation. Biochemistry, 49, 2010
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4KDZ
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![BU of 4kdz by Molmil](/molmil-images/mine/4kdz) | |
3LUF
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![BU of 3luf by Molmil](/molmil-images/mine/3luf) | Structure of probable two-component system response regulator/GGDEF domain protein | Descriptor: | DIMETHYL SULFOXIDE, MAGNESIUM ION, Two-component system response regulator/GGDEF domain protein | Authors: | Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-02-17 | Release date: | 2010-03-02 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structure of probable two-component system response regulator/GGDEF domain protein To be published
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4KF9
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![BU of 4kf9 by Molmil](/molmil-images/mine/4kf9) | Crystal structure of a glutathione transferase family member from ralstonia solanacearum, target efi-501780, with bound gsh coordinated to a zinc ion, ordered active site | Descriptor: | ACETATE ION, GLUTATHIONE, Glutathione s-transferase protein, ... | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-04-26 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a glutathione transferase family member from ralstonia solanacearum, target efi-501780, with bound gsh coordinated to a zinc ion, ordered active site To be Published
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3LV6
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![BU of 3lv6 by Molmil](/molmil-images/mine/3lv6) | Crystal structure of the mutant I218F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase | Authors: | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | Deposit date: | 2010-02-19 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.451 Å) | Cite: | Conformational changes in orotidine 5'-monophosphate decarboxylase: "remote" residues that stabilize the active conformation. Biochemistry, 49, 2010
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3LY0
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![BU of 3ly0 by Molmil](/molmil-images/mine/3ly0) | Crystal structure of metallo peptidase from Rhodobacter sphaeroides liganded with phosphinate mimic of dipeptide L-Ala-D-Ala | Descriptor: | (2R)-3-[(R)-[(1R)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, Dipeptidase AC. Metallo peptidase. MEROPS family M19, ZINC ION | Authors: | Fedorov, A.A, Fedorov, E.V, Cummings, J, Raushel, F.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-02-25 | Release date: | 2010-03-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.399 Å) | Cite: | Crystal structure of metallo peptidase from Rhodobacter sphaeroides
liganded with phosphinate mimic of dipeptide L-Ala-D-Ala To be Published
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4KBX
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![BU of 4kbx by Molmil](/molmil-images/mine/4kbx) | Crystal structure of the pyridoxal-5'-phosphate dependent protein yhfx from escherichia coli | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Xiang, D.F, Raushel, F.M, Almo, S.C. | Deposit date: | 2013-04-24 | Release date: | 2014-05-21 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Crystal structure of the pyridoxal-5'-phosphate dependent protein yhfx from escherichia coli To be Published
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3LX6
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![BU of 3lx6 by Molmil](/molmil-images/mine/3lx6) | |