3VRP
 
 | | Crystal structure of the tyrosine kinase binding domain of Cbl-c in complex with phospho-EGFR peptide | | Descriptor: | CALCIUM ION, Epidermal growth factor receptor, Signal transduction protein CBL-C | | Authors: | Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. | | Deposit date: | 2012-04-13 | | Release date: | 2013-03-06 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c.
J.Biochem., 152, 2012
|
|
3VTP
 | | HIV fusion inhibitor MT-C34 | | Descriptor: | Transmembrane protein gp41 | | Authors: | Yao, X, Waltersperger, S, Wang, M, Cui, S. | | Deposit date: | 2012-06-02 | | Release date: | 2012-08-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The M-T hook structure is critical for design of HIV-1 fusion inhibitors.
J.Biol.Chem., 287, 2012
|
|
3VU3
 | |
3VTT
 | |
1EAN
 | | THE RUNX1 Runt domain at 1.70A resolution: A structural switch and specifically bound chloride ions modulate DNA binding | | Descriptor: | CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1 | | Authors: | Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T, Grundstrom, T, Sauer, U.H. | | Deposit date: | 2001-07-13 | | Release date: | 2002-09-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding
J.Mol.Biol., 322, 2002
|
|
2GG0
 | | Novel bacterial methionine aminopeptidase inhibitors | | Descriptor: | COBALT (II) ION, METHYL N-{(2S,3R)-3-AMINO-2-HYDROXY-3-[4-(TRIFLUOROMETHYL)PHENYL]PROPANOYL}ALANYLGLYCINATE, Methionine aminopeptidase, ... | | Authors: | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | | Deposit date: | 2006-03-23 | | Release date: | 2006-06-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
|
|
2GGB
 | | Novel bacterial methionine aminopeptidase inhibitors | | Descriptor: | COBALT (II) ION, METHYL N-[(2S,3R)-3-AMINO-2-HYDROXYHEPTANOYL]-L-SERYL-L-LEUCINATE, Methionine aminopeptidase, ... | | Authors: | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | | Deposit date: | 2006-03-23 | | Release date: | 2006-06-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
|
|
7NOW
 | |
1ED0
 | | NMR structural determination of viscotoxin A3 from Viscum album L. | | Descriptor: | VISCOTOXIN A3 | | Authors: | Romagnoli, S, Ugolini, R, Fogolari, F, Schaller, G, Urech, K, Giannattasio, M, Ragona, L, Molinari, H. | | Deposit date: | 2000-01-26 | | Release date: | 2000-02-04 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | NMR structural determination of viscotoxin A3 from Viscum album L.
Biochem.J., 350, 2000
|
|
1EGU
 | | CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE AT 1.56 A RESOLUTION | | Descriptor: | HYALURONATE LYASE, SULFATE ION | | Authors: | Li, S, Kelly, S.J, Lamani, E, Ferraroni, M, Jedrzejas, M.J. | | Deposit date: | 2000-02-16 | | Release date: | 2001-02-16 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Structural basis of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase.
EMBO J., 19, 2000
|
|
6R79
 | | Structure of IMP-13 metallo-beta-lactamase in apo form (loop open) | | Descriptor: | BETA-MERCAPTOETHANOL, Beta-lactamase, GLYCEROL, ... | | Authors: | Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M. | | Deposit date: | 2019-03-28 | | Release date: | 2020-04-01 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase.
Antimicrob.Agents Chemother., 64, 2020
|
|
3VSO
 | | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt21 | | Descriptor: | (2R)-2-benzyl-3-[4-propoxy-3-({[4-(pyrimidin-2-yl)benzoyl]amino}methyl)phenyl]propanoic acid, Peroxisome proliferator-activated receptor gamma | | Authors: | Oyama, T, Waku, T, Ohashi, M, Morikawa, K, Miyachi, H. | | Deposit date: | 2012-04-30 | | Release date: | 2013-05-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Design and synthesis of a series of alpha-benzyl phenylpropanoic acid-type peroxisome proliferator-activated receptor (PPAR) gamma partial agonists with improved aqueous solubility
Bioorg.Med.Chem., 21, 2013
|
|
1EMZ
 | | SOLUTION STRUCTURE OF FRAGMENT (350-370) OF THE TRANSMEMBRANE DOMAIN OF HEPATITIS C ENVELOPE GLYCOPROTEIN E1 | | Descriptor: | ENVELOPE GLYCOPROTEIN E1 | | Authors: | Op De Beeck, A, Montserret, R, Duvet, S, Cocquerel, L, Cacan, R, Barberot, B, Le Maire, M, Penin, F, Dubuisson, J. | | Deposit date: | 2000-03-20 | | Release date: | 2000-04-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The transmembrane domains of hepatitis C virus envelope glycoproteins E1 and E2 play a major role in heterodimerization.
J.Biol.Chem., 275, 2000
|
|
6RAE
 | | Structural analysis of the Salmonella type III secretion system ATPase InvC | | Descriptor: | CHLORIDE ION, GLYCEROL, Secretory apparatus ATP synthase (Associated with virulence) | | Authors: | Bernal, I, Roemermann, J, Flacht, L, Lunelli, M, Uetrecht, C, Kolbe, M. | | Deposit date: | 2019-04-05 | | Release date: | 2019-08-21 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.049 Å) | | Cite: | Structural analysis of ligand-bound states of the Salmonella type III secretion system ATPase InvC.
Protein Sci., 28, 2019
|
|
1EOL
 | | Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures | | Descriptor: | ALPHA THROMBIN, THROMBIN INHIBITOR P628 | | Authors: | Slon-Usakiewicz, J.J, Sivaraman, J, Li, Y, Cygler, M, Konishi, Y. | | Deposit date: | 2000-03-23 | | Release date: | 2000-05-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
Biochemistry, 39, 2000
|
|
4ZSF
 | | Crystal structure of pre-specific restriction endonuclease BsaWI-DNA complex | | Descriptor: | BsaWI endonuclease, CALCIUM ION, DNA, ... | | Authors: | Tamulaitiene, G, Rutkauskas, M, Grazulis, S, Siksnys, V. | | Deposit date: | 2015-05-13 | | Release date: | 2015-10-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Functional significance of protein assemblies predicted by the crystal structure of the restriction endonuclease BsaWI.
Nucleic Acids Res., 43, 2015
|
|
3W0F
 | | Crystal structure of mouse Endonuclease VIII-LIKE 3 (mNEIL3) | | Descriptor: | Endonuclease 8-like 3, IODIDE ION, ZINC ION | | Authors: | Liu, M, Imamura, K, Averill, A.M, Wallace, S.S, Doublie, S. | | Deposit date: | 2012-10-30 | | Release date: | 2013-01-16 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA
Structure, 21, 2013
|
|
1EXK
 | | SOLUTION STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF THE ESCHERICHIA COLI CHAPERONE PROTEIN DNAJ. | | Descriptor: | DNAJ PROTEIN, ZINC ION | | Authors: | Martinez-Yamout, M, Legge, G.B, Zhang, O, Wright, P.E, Dyson, H.J. | | Deposit date: | 2000-05-03 | | Release date: | 2000-07-26 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the cysteine-rich domain of the Escherichia coli chaperone protein DnaJ.
J.Mol.Biol., 300, 2000
|
|
3VIR
 | | Crystal strcture of Swi5 from fission yeast | | Descriptor: | Mating-type switching protein swi5, octyl beta-D-glucopyranoside | | Authors: | Kuwabara, N, Yamada, N, Hashimoto, H, Sato, M, Iwasaki, H, Shimizu, T. | | Deposit date: | 2011-10-06 | | Release date: | 2012-08-22 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Mechanistic insights into the activation of Rad51-mediated strand exchange from the structure of a recombination activator, the Swi5-Sfr1 complex
Structure, 20, 2012
|
|
2GG8
 | | Novel bacterial methionine aminopeptidase inhibitors | | Descriptor: | COBALT (II) ION, METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-METHYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE, Methionine aminopeptidase, ... | | Authors: | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | | Deposit date: | 2006-03-23 | | Release date: | 2006-06-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
|
|
6RAD
 | | Salmonella ATPase InvC with ADP | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | | Authors: | Bernal, I, Roemermann, J, Flacht, L, Lunelli, M, Uetrecht, C, Kolbe, M. | | Deposit date: | 2019-04-05 | | Release date: | 2019-08-21 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.796 Å) | | Cite: | Structural analysis of ligand-bound states of the Salmonella type III secretion system ATPase InvC.
Protein Sci., 28, 2019
|
|
2GG7
 | | Novel bacterial methionine aminopeptidase inhibitors | | Descriptor: | 3-(5-AMINO-3-IMINO-3H-PYRAZOL-4-YLAZO)-BENZOIC ACID, COBALT (II) ION, Methionine aminopeptidase, ... | | Authors: | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | | Deposit date: | 2006-03-23 | | Release date: | 2006-06-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
|
|
2FXL
 | | Urate oxidase from aspergillus flavus complexed with allantoin | | Descriptor: | 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, Uricase | | Authors: | Gabison, L, Chiadmi, M, Colloc'h, N, Prange, T. | | Deposit date: | 2006-02-06 | | Release date: | 2006-05-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase.
Febs Lett., 580, 2006
|
|
1EHH
 | |
5HWA
 | | Crystal Structure of MH-K1 chitosanase in substrate-bound form | | Descriptor: | 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CACODYLATE ION, ... | | Authors: | Suzuki, M, Saito, A, Ando, A, Miki, K, Saito, J. | | Deposit date: | 2016-01-29 | | Release date: | 2017-02-08 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal structure of the GH-46 subclass III chitosanase from Bacillus circulans MH-K1 in complex with chitotetraose
Biomed.Biochim.Acta, 1868, 2024
|
|
