1MEX
 
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1MG7
 | | Crystal Structure of xol-1 | | Descriptor: | early switch protein xol-1 2.2k splice form | | Authors: | Luz, J.G, Hassig, C.A, Godzik, A, Meyer, B.J, Wilson, I.A. | | Deposit date: | 2002-08-14 | | Release date: | 2003-04-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators
Genes Dev., 17, 2003
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1P1X
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1ONQ
 | | Crystal Structure of CD1a in Complex with a Sulfatide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | Authors: | Zajonc, D.M, Elsliger, M.A, Teyton, L, Wilson, I.A. | | Deposit date: | 2003-02-28 | | Release date: | 2003-08-05 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A.
Nat.Immunol., 4, 2003
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1P4R
 | | Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD | | Descriptor: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Bifunctional purine biosynthesis protein PURH, N-[(S)-(4-{[(2-AMINO-4-HYDROXYQUINAZOLIN-6-YL)(DIHYDROXY)-LAMBDA~4~-SULFANYL]AMINO}PHENYL)(HYDROXY)METHYL]-L-GLUTAMIC ACID, ... | | Authors: | Cheong, C.-G, Greasley, S.E, Horton, P.A, Beardsley, G.P, Wilson, I.A. | | Deposit date: | 2003-04-23 | | Release date: | 2004-03-30 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates
J.Biol.Chem., 279, 2004
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5WKZ
 | | VH1-69 germline antibody predicted from CR6261 | | Descriptor: | Immunoglobulin heavy variable 1-69D,IgG H chain, Lambda-chain (AA -20 to 215), SULFATE ION | | Authors: | Lang, S, Lee, P.S. | | Deposit date: | 2017-07-25 | | Release date: | 2018-08-01 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Anti-idiotypic antibody K1-18 engages VH1-69 precursor and affinity-matured, anti-stem antibodies through mimicry of the HA stem
To Be Published
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5XRQ
 | | Crystal structure of human monoclonal antibody H3v-47 | | Descriptor: | Fab H3v-47 heavy chain, Fab H3v-47 light chain | | Authors: | Zhang, H, Willson, I.A. | | Deposit date: | 2017-06-09 | | Release date: | 2018-07-25 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Nat Commun, 9, 2018
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3K5J
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4U6G
 | | Crystal structure of 10E8 Fab in complex with a hydrocarbon-stapled HIV-1 gp41 MPER peptide | | Descriptor: | 10E8 Fab Heavy Chain, 10E8 Fab Light Chain, SAH-MPER(662-683KKK)(B,q) | | Authors: | Ofek, G, Bird, G.H, Walensky, L.D, Kwong, P.D. | | Deposit date: | 2014-07-28 | | Release date: | 2014-12-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (4.2012 Å) | | Cite: | Structural Fidelity and Neutralizing Antibody Binding Capacity of
Hydrocarbon-Stapled HIV-1 Antigens
To be published
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2IAY
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2ICH
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5HMG
 | | REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | | Authors: | Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C. | | Deposit date: | 1989-09-11 | | Release date: | 1991-01-15 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
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3CM1
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3DEE
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6VO1
 | | BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20J | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Cottrell, C.A, Ward, A.B. | | Deposit date: | 2020-01-29 | | Release date: | 2020-07-01 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.88 Å) | | Cite: | Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
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6VLR
 | | BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2 gp41, ... | | Authors: | Cottrell, C.A, Ward, A.B. | | Deposit date: | 2020-01-24 | | Release date: | 2020-06-24 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (4.42 Å) | | Cite: | Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
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6VN0
 | | BG505 SOSIP.v4.1 in complex with rhesus macaque Fab RM20F | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | Authors: | Cottrell, C.A, Shin, M, Ward, A.B. | | Deposit date: | 2020-01-29 | | Release date: | 2020-06-24 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.25 Å) | | Cite: | Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
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3GF8
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5IHU
 | | Crystal structure of bovine Fab B11 | | Descriptor: | bovine Fab B11 heavy chain, bovine Fab B11 light chain | | Authors: | Stanfield, R, Wilson, I. | | Deposit date: | 2016-02-29 | | Release date: | 2016-10-05 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
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8EH5
 | | Cryo-EM structure of L9 Fab in complex with rsCSP | | Descriptor: | Circumsporozoite protein, L9 Heavy chain, L9 Light chain | | Authors: | Martin, G.M, Ward, A.B. | | Deposit date: | 2022-09-13 | | Release date: | 2023-06-28 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9.
Nat Commun, 14, 2023
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9ARU
 | | COVA2-15 fragment antigen binding in complex with SARS-CoV-2 6P-mut7 S protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVA2-15 heavy chain variable region, ... | | Authors: | Ozorowski, G, Turner, H.L, Ward, A.B. | | Deposit date: | 2024-02-23 | | Release date: | 2025-01-29 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Plant-produced SARS-CoV-2 antibody engineered towards enhanced potency and in vivo efficacy.
Plant Biotechnol J, 23, 2025
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7OPB
 | | IL7R in complex with an antagonist | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ... | | Authors: | Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N. | | Deposit date: | 2021-05-31 | | Release date: | 2022-05-11 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.144 Å) | | Cite: | Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
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5CXT
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8TIM
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2KLA
 | | NMR STRUCTURE OF A PUTATIVE DINITROGENASE (MJ0327) FROM METHANOCOCCUS JANNASCHII | | Descriptor: | Uncharacterized protein MJ0327 | | Authors: | Jaudzems, K, Mohanty, B, Geralt, M, Serrano, P, Wilson, I, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | | Deposit date: | 2009-06-30 | | Release date: | 2009-08-11 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the protein NP_247299.1: comparison with the crystal structure.
Acta Crystallogr.,Sect.F, 66, 2010
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