2XIN
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3ZHM
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![BU of 3zhm by Molmil](/molmil-images/mine/3zhm) | N-terminal domain of the CI repressor from bacteriophage TP901-1 in complex with the OL2 operator half-site | Descriptor: | 5'-D(*AP*CP*GP*TP*GP*AP*AP*CP*TP*TP*GP*CP*AP*CP *TP*TP*GP*A)-3', 5'-D(*AP*GP*TP*TP*CP*AP*CP*GP*TP*TP*CP*AP*AP*GP *TP*GP*CP*A)-3', CI | Authors: | Frandsen, K.H, Rasmussen, K.K, Poulsen, J.N, Lo Leggio, L. | Deposit date: | 2012-12-22 | Release date: | 2013-12-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Binding of the N-Terminal Domain of the Lactococcal Bacteriophage Tp901-1 Ci Repressor to its Target DNA: A Crystallography, Small Angle Scattering, and Nuclear Magnetic Resonance Study. Biochemistry, 52, 2013
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7XLF
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![BU of 7xlf by Molmil](/molmil-images/mine/7xlf) | Crystal structure of CH3-THF complex of methylenetetrahydrofolate reductase from Sphingobium sp. SYK-6 | Descriptor: | 5,10-methylenetetrahydrofolate reductase, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Yu, H.Y, Senda, M, Senda, T. | Deposit date: | 2022-04-21 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structural of methylenetetrahydrofolate reductase from Sphingobium sp. SYK-6 To Be Published
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7XG9
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6AWF
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![BU of 6awf by Molmil](/molmil-images/mine/6awf) | Escherichia coli quinol:fumarate reductase crystallized without dicarboxylate | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Iverson, T.M. | Deposit date: | 2017-09-05 | Release date: | 2017-12-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | New crystal forms of the integral membrane Escherichia coli quinol:fumarate reductase suggest that ligands control domain movement. J. Struct. Biol., 202, 2018
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3ZHI
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![BU of 3zhi by Molmil](/molmil-images/mine/3zhi) | N-terminal domain of the CI repressor from bacteriophage TP901-1 | Descriptor: | CI | Authors: | Frandsen, K.H, Rasmussen, K.K, Poulsen, J.N, Lo Leggio, L. | Deposit date: | 2012-12-21 | Release date: | 2013-12-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Binding of the N-Terminal Domain of the Lactococcal Bacteriophage Tp901-1 Ci Repressor to its Target DNA: A Crystallography, Small Angle Scattering, and Nuclear Magnetic Resonance Study. Biochemistry, 52, 2013
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4EM7
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![BU of 4em7 by Molmil](/molmil-images/mine/4em7) | Crystal structure of a topoisomerase ATP inhibitor | Descriptor: | 3-[3-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]propanoic acid, DNA topoisomerase IV, B subunit | Authors: | Boriack-Sjodin, P.A, Manchester, J. | Deposit date: | 2012-04-11 | Release date: | 2012-08-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV. Bioorg.Med.Chem.Lett., 22, 2012
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4EMV
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![BU of 4emv by Molmil](/molmil-images/mine/4emv) | Crystal structure of a topoisomerase ATP inhibitor | Descriptor: | 5-{2-(ethylcarbamoyl)-4-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl}pyridine-3-carboxylic acid, DNA topoisomerase IV, B subunit | Authors: | Boriack-Sjodin, P.A, Manchester, J, Hull, K. | Deposit date: | 2012-04-12 | Release date: | 2012-08-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV. Bioorg.Med.Chem.Lett., 22, 2012
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4ZJS
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![BU of 4zjs by Molmil](/molmil-images/mine/4zjs) | Crystal structure of a chimeric acetylcholine binding protein from Aplysia Californica (Ac-AChBP) containing the main immunogenic region (MIR) from the human alpha 1 subunit of the muscle nicotinic acetylcholine receptor in complex with anatoxin-A. | Descriptor: | 1-[(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl]ethanone, Acetylcholine receptor subunit alpha,Soluble acetylcholine receptor,Acetylcholine receptor subunit alpha,Soluble acetylcholine receptor | Authors: | Talley, T.T, Bobango, J, Wu, J, Park, J.F, Luo, J, Lindsatrom, J, Taylor, P. | Deposit date: | 2015-04-29 | Release date: | 2015-05-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2301 Å) | Cite: | Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity. J. Neurosci., 29, 2009
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6EBB
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4HWK
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![BU of 4hwk by Molmil](/molmil-images/mine/4hwk) | Crystal structure of human sepiapterin reductase in complex with sulfapyridine | Descriptor: | 4-amino-N-(pyridin-2-yl)benzenesulfonamide, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Groenlund Pedersen, M, Pojer, F, Johnsson, K. | Deposit date: | 2012-11-08 | Release date: | 2013-06-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Tetrahydrobiopterin biosynthesis as an off-target of sulfa drugs. Science, 340, 2013
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2BYZ
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2BZ4
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![BU of 2bz4 by Molmil](/molmil-images/mine/2bz4) | structure of E.coli KAS I H298Q mutant | Descriptor: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION, SULFATE ION | Authors: | Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A. | Deposit date: | 2005-08-10 | Release date: | 2006-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J., 273, 2006
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2BYY
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![BU of 2byy by Molmil](/molmil-images/mine/2byy) | E.coli KAS I H298E Mutation | Descriptor: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION | Authors: | Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A. | Deposit date: | 2005-08-09 | Release date: | 2006-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J., 273, 2006
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2BZ3
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![BU of 2bz3 by Molmil](/molmil-images/mine/2bz3) | Structure of E.coli KAS I H298E mutant in complex with C12 fatty acid | Descriptor: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION, LAURIC ACID, ... | Authors: | Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A. | Deposit date: | 2005-08-10 | Release date: | 2006-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J., 273, 2006
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3ZDO
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![BU of 3zdo by Molmil](/molmil-images/mine/3zdo) | Tetramerization domain of Measles virus phosphoprotein | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, PHOSPHOPROTEIN | Authors: | Communie, G, Crepin, T, Jensen, M.R, Blackledge, M, Ruigrok, R.W.H. | Deposit date: | 2012-11-29 | Release date: | 2013-04-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure of the Tetramerization Domain of Measles Virus Phosphoprotein. J.Virol., 87, 2013
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5D9S
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4CEL
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![BU of 4cel by Molmil](/molmil-images/mine/4cel) | ACTIVE-SITE MUTANT D214N DETERMINED AT PH 6.0 WITH NO LIGAND BOUND IN THE ACTIVE SITE | Descriptor: | 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION | Authors: | Divne, C, Stahlberg, J, Jones, T.A. | Deposit date: | 1996-08-24 | Release date: | 1997-03-12 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Activity studies and crystal structures of catalytically deficient mutants of cellobiohydrolase I from Trichoderma reesei. J.Mol.Biol., 264, 1996
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2P05
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![BU of 2p05 by Molmil](/molmil-images/mine/2p05) | Structural Insights into the Evolution of a Non-Biological Protein | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... | Authors: | Smith, M, Rosenow, M, Wang, M, Allen, J.P, Szostak, J.W, Chaput, J.C. | Deposit date: | 2007-02-28 | Release date: | 2007-06-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PLoS ONE, 2, 2007
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7M2G
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![BU of 7m2g by Molmil](/molmil-images/mine/7m2g) | INTERLEUKIN-2 (human) mutant P65K, C125S | Descriptor: | GLYCEROL, Interleukin-2, SULFATE ION | Authors: | Ptacin, J.L, Milla, M.E, Steinbacher, S, Maskos, K, Thomsen, M. | Deposit date: | 2021-03-16 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism. Nat Commun, 12, 2021
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4RQN
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![BU of 4rqn by Molmil](/molmil-images/mine/4rqn) | Crystal structure of the native BICC1 SAM Domain R924E mutant | Descriptor: | Protein bicaudal C homolog 1, ZINC ION | Authors: | Leettola, C.N, Cascio, D, Bowie, J.U. | Deposit date: | 2014-11-03 | Release date: | 2016-01-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6. Structure, 26, 2018
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4RQM
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![BU of 4rqm by Molmil](/molmil-images/mine/4rqm) | Crystal structure of the SeMET BICC1 SAM Domain R924E mutant | Descriptor: | Protein bicaudal C homolog 1, ZINC ION | Authors: | Leettola, C.N, Cascio, D, Bowie, J.U. | Deposit date: | 2014-11-03 | Release date: | 2016-01-27 | Last modified: | 2019-10-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6. Structure, 26, 2018
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2P09
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![BU of 2p09 by Molmil](/molmil-images/mine/2p09) | Structural Insights into the Evolution of a Non-Biological Protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... | Authors: | Smith, M, Rosenow, M, Wang, M, Allen, J.P, Szostak, J.W, Chaput, J.C. | Deposit date: | 2007-02-28 | Release date: | 2007-06-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PLoS ONE, 2, 2007
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5DDH
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2XIM
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![BU of 2xim by Molmil](/molmil-images/mine/2xim) | ARGININE RESIDUES AS STABILIZING ELEMENTS IN PROTEINS | Descriptor: | D-XYLOSE ISOMERASE, MAGNESIUM ION, Xylitol | Authors: | Mrabet, N.T, Van Denbroek, A, Van Den Brande, I, Stanssens, P, Laroche, Y, Lambeir, A.-M, Matthyssens, G, Jenkins, J, Chiadmi, M, Vantilbeurgh, H, Rey, F, Janin, J, Quax, W.J, Lasters, I, Demaeyer, M, Wodak, S.J. | Deposit date: | 1991-05-29 | Release date: | 1993-04-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Arginine residues as stabilizing elements in proteins. Biochemistry, 31, 1992
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