3ZXJ
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![BU of 3zxj by Molmil](/molmil-images/mine/3zxj) | Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, HIAXHD3, ... | Authors: | McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-08-11 | Release date: | 2012-04-18 | Last modified: | 2012-05-02 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains. Proc.Natl.Acad.Sci.USA, 109, 2012
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3ZXK
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![BU of 3zxk by Molmil](/molmil-images/mine/3zxk) | Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIAXHD3, alpha-L-arabinofuranose-(1-2)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | Authors: | McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-08-11 | Release date: | 2012-04-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains. Proc.Natl.Acad.Sci.USA, 109, 2012
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5HI1
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![BU of 5hi1 by Molmil](/molmil-images/mine/5hi1) | Backbone Modifications in the Protein GB1 Helix: Aib24, beta-3-Lys28, beta-3-Lys31, Aib35 | Descriptor: | ACETATE ION, Immunoglobulin G-binding protein G | Authors: | Tavenor, N.A, Reinert, Z.E, Lengyel, G.A, Griffith, B.D, Horne, W.S. | Deposit date: | 2016-01-11 | Release date: | 2016-02-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Comparison of design strategies for alpha-helix backbone modification in a protein tertiary fold. Chem.Commun.(Camb.), 52, 2016
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3ZXL
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![BU of 3zxl by Molmil](/molmil-images/mine/3zxl) | Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HIAXHD3 | Authors: | McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-08-11 | Release date: | 2012-04-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.871 Å) | Cite: | Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains. Proc.Natl.Acad.Sci.USA, 109, 2012
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2YJ1
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![BU of 2yj1 by Molmil](/molmil-images/mine/2yj1) | Puma BH3 foldamer in complex with Bcl-xL | Descriptor: | ALPHA-BETA-PUMA BH3 FOLDAMER, BCL-2-LIKE PROTEIN 1 | Authors: | Lee, E.F, Smith, B.J, Horne, W.S, Mayer, K.N, Evangelista, M, Colman, P.M, Gellman, S.H, Fairlie, W.D. | Deposit date: | 2011-05-18 | Release date: | 2011-10-12 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural Basis of Bcl-Xl Recognition by a Bh3-Mimetic Alpha-Beta-Peptide Generated Via Sequence-Based Design Chembiochem, 12, 2011
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8T0G
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8T0H
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8T0I
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3BBZ
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![BU of 3bbz by Molmil](/molmil-images/mine/3bbz) | Structure of the nucleocapsid-binding domain from the mumps virus phosphoprotein | Descriptor: | BROMIDE ION, FORMIC ACID, P protein | Authors: | Kingston, R.L, Gay, L.S, Baase, W.S, Matthews, B.W. | Deposit date: | 2007-11-11 | Release date: | 2008-05-27 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the nucleocapsid-binding domain from the mumps virus polymerase; an example of protein folding induced by crystallization J.Mol.Biol., 379, 2008
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3C3H
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![BU of 3c3h by Molmil](/molmil-images/mine/3c3h) | alpha/beta-Peptide helix bundles: A GCN4-pLI analogue with an (alpha-alpha-beta) backbone and cyclic beta residues | Descriptor: | alpha/beta-peptide based on the GCN4-pLI side chain sequence, with an (alpha-alpha-beta) backbone and cyclic beta-residues at positions 1, 4, ... | Authors: | Horne, W.S, Price, J.L, Gellman, S.H. | Deposit date: | 2008-01-28 | Release date: | 2008-06-17 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2Y8K
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![BU of 2y8k by Molmil](/molmil-images/mine/2y8k) | Structure of CtGH5-CBM6, an arabinoxylan-specific xylanase. | Descriptor: | CALCIUM ION, CARBOHYDRATE BINDING FAMILY 6, GLYCEROL, ... | Authors: | Firbank, S.J, Correia, M.A, Mazumder, K, Bras, J.L, Zhu, Y, Lewis, R.J, York, W.S, Fontes, C.M, Gilbert, H.J. | Deposit date: | 2011-02-07 | Release date: | 2011-02-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structure and Function of an Arabinoxylan-Specific Xylanase. J.Biol.Chem., 286, 2011
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3C3G
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![BU of 3c3g by Molmil](/molmil-images/mine/3c3g) | alpha/beta-Peptide helix bundles: The GCN4-pLI side chain sequence on an (alpha-alpha-beta) backbone | Descriptor: | GLYCEROL, alpha/beta peptide with the GCN4-pLI side chain sequence on an (alpha-alpha-beta) backbone | Authors: | Horne, W.S, Price, J.L, Gellman, S.H. | Deposit date: | 2008-01-28 | Release date: | 2008-06-17 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C3F
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3CB3
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![BU of 3cb3 by Molmil](/molmil-images/mine/3cb3) | Crystal structure of L-Talarate dehydratase from Polaromonas sp. JS666 complexed with Mg and L-glucarate | Descriptor: | L-GLUCARIC ACID, MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme | Authors: | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-02-21 | Release date: | 2008-03-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of L-Talarate dehydratase from Polaromonas sp. JS666 complexed with Mg and L-glucarate. To be Published
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7NRO
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![BU of 7nro by Molmil](/molmil-images/mine/7nro) | Crystal structure of AlkB in complex with manganese and N-(4-((6-((carboxymethyl)carbamoyl)-5-hydroxypyridin-2-yl)amino)phenyl)-N-oxohydroxylammonium | Descriptor: | 2-[[6-[(4-nitrophenyl)amino]-3-oxidanyl-pyridin-2-yl]carbonylamino]ethanoic acid, Alpha-ketoglutarate-dependent dioxygenase AlkB, MANGANESE (II) ION | Authors: | Shishodia, S, Maheswaran, P, Leissing, T, Aik, W.S, McDonough, M.A, Schofield, C.J. | Deposit date: | 2021-03-04 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors. J.Med.Chem., 64, 2021
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1I7E
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![BU of 1i7e by Molmil](/molmil-images/mine/1i7e) | C-Terminal Domain Of Mouse Brain Tubby Protein bound to Phosphatidylinositol 4,5-bis-phosphate | Descriptor: | L-ALPHA-GLYCEROPHOSPHO-D-MYO-INOSITOL-4,5-BIS-PHOSPHATE, TUBBY PROTEIN | Authors: | Santagata, S, Boggon, T.J, Baird, C.L, Shan, W.S, Shapiro, L. | Deposit date: | 2001-03-08 | Release date: | 2001-06-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | G-protein signaling through tubby proteins. Science, 292, 2001
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1SQ0
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![BU of 1sq0 by Molmil](/molmil-images/mine/1sq0) | Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom Resolution | Descriptor: | Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin], Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II] | Authors: | Dumas, J.J, Kumar, R, McDonagh, T, Sullivan, F, Stahl, M.L, Somers, W.S, Mosyak, L. | Deposit date: | 2004-03-17 | Release date: | 2004-04-13 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations J.Biol.Chem., 279, 2004
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5BMI
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![BU of 5bmi by Molmil](/molmil-images/mine/5bmi) | Nitroxide Spin Labels in Protein GB1: T44 Mutant, Crystal Form A | Descriptor: | Immunoglobulin G-binding protein G, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | Authors: | Cunningham, T.C, Horne, W.S, Saxena, S. | Deposit date: | 2015-05-22 | Release date: | 2016-04-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Rotameric preferences of a protein spin label at edge-strand beta-sheet sites. Protein Sci., 25, 2016
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5BMH
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![BU of 5bmh by Molmil](/molmil-images/mine/5bmh) | Nitroxide Spin Labels in Protein GB1: T44 Mutant, Crystal Form B | Descriptor: | Immunoglobulin G-binding protein G, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | Authors: | Cunningham, T.C, Horne, W.S, Saxena, S. | Deposit date: | 2015-05-22 | Release date: | 2016-04-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Rotameric preferences of a protein spin label at edge-strand beta-sheet sites. Protein Sci., 25, 2016
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5BMG
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![BU of 5bmg by Molmil](/molmil-images/mine/5bmg) | Nitroxide Spin Labels in Protein GB1: E15 Mutant | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Immunoglobulin G-binding protein G, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | Authors: | Cunningham, T.C, Horne, W.S, Saxena, S. | Deposit date: | 2015-05-22 | Release date: | 2016-04-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Rotameric preferences of a protein spin label at edge-strand beta-sheet sites. Protein Sci., 25, 2016
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5DIC
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5DQV
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![BU of 5dqv by Molmil](/molmil-images/mine/5dqv) | The crystal structure of Bacillus subtilis YpgQ | Descriptor: | NICKEL (II) ION, Uncharacterized protein | Authors: | Jeon, Y.J, Song, W.S, Yoon, S.I. | Deposit date: | 2015-09-15 | Release date: | 2016-04-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and biochemical characterization of bacterial YpgQ protein reveals a metal-dependent nucleotide pyrophosphohydrolase J.Struct.Biol., 195, 2016
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5BT2
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![BU of 5bt2 by Molmil](/molmil-images/mine/5bt2) | MeCP2 MBD domain (A140V) in complex with methylated DNA | Descriptor: | DNA (5'-D(*AP*TP*AP*GP*AP*AP*GP*AP*AP*TP*TP*CP*(5CM)P*GP*TP*TP*CP*CP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*GP*GP*AP*AP*(5CM)P*GP*GP*AP*AP*TP*TP*CP*TP*TP*CP*TP*A)-3'), Methyl-CpG-binding protein 2 | Authors: | Ho, K.L, Chia, J.Y, Tan, W.S, Ng, C.L, Hu, N.J, Foo, H.L. | Deposit date: | 2015-06-02 | Release date: | 2016-08-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence. Sci Rep, 6, 2016
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5DQW
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1WVE
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![BU of 1wve by Molmil](/molmil-images/mine/1wve) | p-Cresol Methylhydroxylase: Alteration of the Structure of the Flavoprotein Subunit upon its Binding to the Cytochrome Subunit | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-cresol dehydrogenase [hydroxylating] cytochrome c subunit, 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit, ... | Authors: | Cunane, L.M, Chen, Z.-W, McIntire, W.S, Mathews, F.S. | Deposit date: | 2004-12-15 | Release date: | 2005-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | p-Cresol Methylhydroxylase: Alteration of the Structure of the Flavoprotein Subunit upon Its Binding to the Cytochrome Subunit Biochemistry, 44, 2005
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