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8VUL
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BU of 8vul by Molmil
Human GluN1-2A with Fab 003-102 Local refinement of ATD
Descriptor: 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ...
Authors:Michalski, K, Furukawa, H.
Deposit date:2024-01-29
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.83 Å)
Cite:Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
8VUJ
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BU of 8vuj by Molmil
Human GluN1-2A with Fab 003-102
Descriptor: 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ...
Authors:Michalski, K, Furukawa, H.
Deposit date:2024-01-29
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
8VUU
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BU of 8vuu by Molmil
Human GluN1-2B with Fab 007-168
Descriptor: 007-168 Heavy, 007-168 Light, Glutamate receptor ionotropic, ...
Authors:Michalski, K, Furukawa, H.
Deposit date:2024-01-29
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
8VUR
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BU of 8vur by Molmil
Human GluN1-2A with IgG 003-102 WT conformation
Descriptor: 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ...
Authors:Michalski, K, Furukawa, H.
Deposit date:2024-01-29
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
8VUT
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BU of 8vut by Molmil
Human GluN1-2A with IgG 008-218
Descriptor: 008-218 Heavy, 008-218 Light, Glutamate receptor ionotropic, ...
Authors:Michalski, K, Furukawa, H.
Deposit date:2024-01-29
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
8VUV
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BU of 8vuv by Molmil
Human GluN1-2B with Fab 007-168 Local refinement of ATD
Descriptor: 007-168 Heavy, 007-168 Light, Glutamate receptor ionotropic, ...
Authors:Michalski, K, Furukawa, H.
Deposit date:2024-01-29
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
8VUY
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BU of 8vuy by Molmil
Rat GluN1-2B with Fab 003-102
Descriptor: 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ...
Authors:Michalski, K, Furukawa, H.
Deposit date:2024-01-30
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
8VUS
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BU of 8vus by Molmil
Human GluN1-2A with IgG 007-168
Descriptor: 007-168 Heavy, 007-168 Light, Glutamate receptor ionotropic, ...
Authors:Michalski, K, Furukawa, H.
Deposit date:2024-01-29
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
7TE9
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BU of 7te9 by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1
Descriptor: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
Authors:Tajima, N, Furukawa, H.
Deposit date:2022-01-04
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
8G18
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BU of 8g18 by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-108
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2023-02-01
Release date:2023-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model.
Acs Chem Neurosci, 14, 2023
7TES
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BU of 7tes by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in Non-active1 conformation
Descriptor: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
Authors:Tajima, N, Furukawa, H.
Deposit date:2022-01-05
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TE4
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BU of 7te4 by Molmil
Crystal structure of Fab2 anti-GluN2B antibody
Descriptor: Fab anti-GluN2B antibody, heavy chain, Fab2 anti-GluN2B antibody, ...
Authors:Tajima, N, Furukawa, H.
Deposit date:2022-01-04
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.456 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TEB
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BU of 7teb by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 non-active1-like
Descriptor: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
Authors:Tajima, N, Furukawa, H.
Deposit date:2022-01-04
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TE6
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BU of 7te6 by Molmil
Crystal structure of GluN1b-2B ATD complexed to Fab5 anti-GluN2B antibody
Descriptor: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
Authors:Regan, M, Tajima, N, Furukawa, H.
Deposit date:2022-01-04
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.55 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TER
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BU of 7ter by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 non-active2 conformation
Descriptor: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
Authors:Tajima, N, Furukawa, H.
Deposit date:2022-01-05
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (5.23 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TEE
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BU of 7tee by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 Non-active2-like
Descriptor: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
Authors:Tajima, N, Furukawa, H.
Deposit date:2022-01-04
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (6.59 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TET
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BU of 7tet by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in non-active2-like conformation
Descriptor: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
Authors:Tajima, N, Furukawa, H.
Deposit date:2022-01-05
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (4.45 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TEQ
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BU of 7teq by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 active conformation
Descriptor: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
Authors:Tajima, N, Furukawa, H.
Deposit date:2022-01-05
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (7.51 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
5B3J
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BU of 5b3j by Molmil
Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
Descriptor: Fab, heavy chain, light chain, ...
Authors:Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H.
Deposit date:2016-03-01
Release date:2016-05-11
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
Nature, 534, 2016
6E7W
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BU of 6e7w by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-115
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7S
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BU of 6e7s by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7U
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BU of 6e7u by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-31
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7X
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BU of 6e7x by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-97
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7V
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BU of 6e7v by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-88
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7T
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BU of 6e7t by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019

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