3R47
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![BU of 3r47 by Molmil](/molmil-images/mine/3r47) | Crystal structure of a 6-helix coiled coil CC-hex-H24 | Descriptor: | BROMIDE ION, coiled coil helix L24H | Authors: | Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. | Deposit date: | 2011-03-17 | Release date: | 2011-11-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5002 Å) | Cite: | A de novo peptide hexamer with a mutable channel. Nat.Chem.Biol., 7, 2011
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6IEG
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![BU of 6ieg by Molmil](/molmil-images/mine/6ieg) | Crystal structure of human MTR4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4, MAGNESIUM ION | Authors: | Chen, J.Y, Yun, C.H. | Deposit date: | 2018-09-14 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction. Genes Dev., 33, 2019
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5D2A
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![BU of 5d2a by Molmil](/molmil-images/mine/5d2a) | Bifunctional dendrimers | Descriptor: | 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, Fucose-binding lectin, ... | Authors: | Michaud, G, Visini, R, Stocker, A, Darbre, T, Reymond, J.L. | Deposit date: | 2015-08-05 | Release date: | 2016-02-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.134 Å) | Cite: | Overcoming antibiotic resistance inPseudomonas aeruginosabiofilms using glycopeptide dendrimers. Chem Sci, 7, 2016
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4XB6
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![BU of 4xb6 by Molmil](/molmil-images/mine/4xb6) | Structure of the E. coli C-P lyase core complex | Descriptor: | Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ... | Authors: | Brodersen, D.E. | Deposit date: | 2014-12-16 | Release date: | 2015-08-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into the bacterial carbon-phosphorus lyase machinery. Nature, 525, 2015
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6NM3
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![BU of 6nm3 by Molmil](/molmil-images/mine/6nm3) | NMR structure of WW295 | Descriptor: | WW295 peptide | Authors: | Wang, G, Zarena, D. | Deposit date: | 2019-01-10 | Release date: | 2020-07-15 | Last modified: | 2020-09-09 | Method: | SOLUTION NMR | Cite: | Two distinct amphipathic peptide antibiotics with systemic efficacy. Proc.Natl.Acad.Sci.USA, 117, 2020
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6OQP
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![BU of 6oqp by Molmil](/molmil-images/mine/6oqp) | U-AITx-Ate1 | Descriptor: | SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE | Authors: | Elnahriry, K.A, Wai, D.C.C, Norton, R.S. | Deposit date: | 2019-04-28 | Release date: | 2019-07-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa. Toxicon, 168, 2019
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6EZD
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![BU of 6ezd by Molmil](/molmil-images/mine/6ezd) | |
2L6L
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![BU of 2l6l by Molmil](/molmil-images/mine/2l6l) | Solution structure of human J-protein co-chaperone, Dph4 | Descriptor: | DnaJ homolog subfamily C member 24, ZINC ION | Authors: | Thakur, A, Chitoor, B.S, Atreya, H.S, Silva, P.D. | Deposit date: | 2010-11-23 | Release date: | 2011-12-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and mechanistic insights into novel iron-mediated moonlighting functions of human J-protein cochaperone, Dph4. J.Biol.Chem., 287, 2012
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6WPO
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![BU of 6wpo by Molmil](/molmil-images/mine/6wpo) | |
6WUX
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![BU of 6wux by Molmil](/molmil-images/mine/6wux) | |
4XW2
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![BU of 4xw2 by Molmil](/molmil-images/mine/4xw2) | Structural basis for simvastatin competitive antagonism of complement receptor 3 | Descriptor: | Integrin alpha-M, MAGNESIUM ION, Simvastatin acid | Authors: | Bajic, G, Jensen, M.R, Vorup-Jensen, T, Andersen, G.R. | Deposit date: | 2015-01-28 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural Basis for Simvastatin Competitive Antagonism of Complement Receptor 3. J.Biol.Chem., 291, 2016
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6CKU
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![BU of 6cku by Molmil](/molmil-images/mine/6cku) | Solution structure of the zebrafish granulin AaE | Descriptor: | Granulin-AaE | Authors: | Wang, P, Ni, F. | Deposit date: | 2018-02-28 | Release date: | 2018-06-13 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structure dissection of zebrafish progranulins identifies a well-folded granulin/epithelin module protein with pro-cell survival activities. Protein Sci., 27, 2018
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8AW2
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![BU of 8aw2 by Molmil](/molmil-images/mine/8aw2) | Mouse serotonin 5-HT3A receptor in complex with vortioxetine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... | Authors: | Lopez-Sanchez, U, Nury, H. | Deposit date: | 2022-08-29 | Release date: | 2024-03-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors. Nat.Struct.Mol.Biol., 2024
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8AXD
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![BU of 8axd by Molmil](/molmil-images/mine/8axd) | Human serotonin 5-HT3A receptor (apo, resting conformation) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A | Authors: | Lopez-Sanchez, U, Nury, H. | Deposit date: | 2022-08-31 | Release date: | 2024-03-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors. Nat.Struct.Mol.Biol., 2024
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8BLA
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![BU of 8bla by Molmil](/molmil-images/mine/8bla) | |
8BL8
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![BU of 8bl8 by Molmil](/molmil-images/mine/8bl8) | Human serotonin 5-HT3A receptor (apo, active/distorted conformation) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A | Authors: | Lopez-Sanchez, U, Nury, H. | Deposit date: | 2022-11-09 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors. Nat.Struct.Mol.Biol., 2024
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8BLB
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2LTC
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![BU of 2ltc by Molmil](/molmil-images/mine/2ltc) | Fas1-4, R555W | Descriptor: | Transforming growth factor-beta-induced protein ig-h3 | Authors: | Underhaug, J, Nielsen, N, Runager, K. | Deposit date: | 2012-05-16 | Release date: | 2013-08-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization. Biochim.Biophys.Acta, 1834, 2013
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5LJO
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![BU of 5ljo by Molmil](/molmil-images/mine/5ljo) | E. coli BAM complex (BamABCDE) by cryoEM | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | Authors: | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Schffrin, B, Calabrese, A.N, Ashcroft, A.E, Brockwell, D.J. | Deposit date: | 2016-07-19 | Release date: | 2016-10-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Lateral opening in the intact beta-barrel assembly machinery captured by cryo-EM. Nat Commun, 7, 2016
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5N5K
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2N24
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2LTB
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![BU of 2ltb by Molmil](/molmil-images/mine/2ltb) | Wild-type FAS1-4 | Descriptor: | Transforming growth factor-beta-induced protein ig-h3 | Authors: | Underhaug, J, Nielsen, N, Runager, K. | Deposit date: | 2012-05-16 | Release date: | 2013-08-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization. Biochim.Biophys.Acta, 1834, 2013
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4J5S
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![BU of 4j5s by Molmil](/molmil-images/mine/4j5s) | TARG1 (C6orf130), Terminal ADP-ribose Glycohydrolase 1 ADP-ribose complex | Descriptor: | 1,2-ETHANEDIOL, 1,3,2-DIOXABOROLAN-2-OL, BORATE ION, ... | Authors: | Schellenberg, M.J, Appel, C.D, Krahn, J, Williams, R.S. | Deposit date: | 2013-02-09 | Release date: | 2013-03-27 | Last modified: | 2013-07-03 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease. Embo J., 32, 2013
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4K6A
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![BU of 4k6a by Molmil](/molmil-images/mine/4k6a) | Revised Crystal Structure of apo-form of Triosephosphate Isomerase (tpiA) from Escherichia coli at 1.8 Angstrom Resolution. | Descriptor: | SODIUM ION, Triosephosphate isomerase | Authors: | Minasov, G, Kuhn, M, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Grimshaw, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-04-15 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. PLoS ONE, 9, 2014
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4VGC
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![BU of 4vgc by Molmil](/molmil-images/mine/4vgc) | GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | Descriptor: | D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION | Authors: | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | Deposit date: | 1997-05-01 | Release date: | 1997-11-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Biochemistry, 37, 1998
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