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6I95
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BU of 6i95 by Molmil
R2-like ligand-binding oxidase G68L mutant with anaerobically reconstituted Mn/Fe cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, OCTANOIC ACID (CAPRYLIC ACID), ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2018-11-22
Release date:2019-10-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.646 Å)
Cite:Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins.
J.Biol.Chem., 294, 2019
6I94
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BU of 6i94 by Molmil
R2-like ligand-binding oxidase G68L mutant with non-activated Mn/Mn cofactor (after aerobic reconstitution with Mn and Fe)
Descriptor: MANGANESE (II) ION, OCTANOIC ACID (CAPRYLIC ACID), Ribonucleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2018-11-22
Release date:2019-10-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins.
J.Biol.Chem., 294, 2019
6I92
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BU of 6i92 by Molmil
R2-like ligand-binding oxidase G68F mutant with anaerobically reconstituted Mn/Fe cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, Ribonucleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2018-11-22
Release date:2019-10-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins.
J.Biol.Chem., 294, 2019
2UW2
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BU of 2uw2 by Molmil
Crystal structure of human ribonucleotide reductase subunit R2
Descriptor: FE (III) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT
Authors:Welin, M, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Stenmark, P, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
Deposit date:2007-03-16
Release date:2007-04-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Ribonucleotide Reductase Subunit R2
To be Published
2UVQ
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BU of 2uvq by Molmil
Crystal structure of human uridine-cytidine kinase 1 in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, URIDINE-CYTIDINE KINASE 1
Authors:Kosinska, U, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E.P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Uppsten, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Nordlund, P.
Deposit date:2007-03-13
Release date:2007-03-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Human Uridine-Cytidine Kinase 1
To be Published
2OXC
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BU of 2oxc by Molmil
Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Probable ATP-dependent RNA helicase DDX20
Authors:Karlberg, T, Ogg, D, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2007-02-20
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Human DEAD-box RNA helicase DDX20
To be Published
2Y3M
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BU of 2y3m by Molmil
Structure of the extra-membranous domain of the secretin HofQ from Actinobacillus actinomycetemcomitans
Descriptor: FORMIC ACID, GLYCEROL, PROTEIN TRANSPORT PROTEIN HOFQ
Authors:Tarry, M, Jaaskelainen, M, Tuominen, H, Ihalin, R, Hogbom, M.
Deposit date:2010-12-21
Release date:2011-04-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Extra-Membranous Domains of the Competence Protein Hofq Show DNA Binding, Flexibility and a Shared Fold with Type I Kh Domains.
J.Mol.Biol., 409, 2011
1RSR
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BU of 1rsr by Molmil
azide complex of the diferrous F208A mutant R2 subunit of ribonucleotide reductase
Descriptor: AZIDE ION, FE (II) ION, MERCURY (II) ION, ...
Authors:Andersson, M.E, Hogbom, M, Rinaldo-Matthis, A, Andersson, K.K, Sjoberg, B.M, Nordlund, P.
Deposit date:2003-12-10
Release date:2003-12-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of an Azide Complex of the Diferrous R2 Subunit of Ribonucleotide Reductase Displays a Novel Carboxylate Shift with Important Mechanistic Implications for Diiron-Catalyzed Oxygen Activation
J.Am.Chem.Soc., 121, 1999
6NWR
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BU of 6nwr by Molmil
Thioester acyl-intermediate of Apolipoprotein N-acyltransferase (Lnt)
Descriptor: Apolipoprotein N-acyltransferase, DODECANE, DODECYL-BETA-D-MALTOSIDE
Authors:Wiseman, B, Hogbom, M.
Deposit date:2019-02-07
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Conformational changes in Apolipoprotein N-acyltransferase (Lnt).
Sci Rep, 10, 2020
6Y2N
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BU of 6y2n by Molmil
Crystal structure of ribonucleotide reductase R2 subunit solved by serial synchrotron crystallography
Descriptor: FE (III) ION, MANGANESE (III) ION, Ribonucleoside-diphosphate reductase subunit beta
Authors:Shilova, A, Lebrette, H, Aurelius, O, Hogbom, M, Mueller, U.
Deposit date:2020-02-17
Release date:2020-10-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Current status and future opportunities for serial crystallography at MAX IV Laboratory.
J.Synchrotron Radiat., 27, 2020
4HR4
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BU of 4hr4 by Molmil
R2-like ligand-binding oxidase with anaerobically reconstituted metal cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2012-10-26
Release date:2013-10-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
4HR5
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BU of 4hr5 by Molmil
R2-like ligand-binding oxidase without metal cofactor
Descriptor: PALMITIC ACID, Ribonuleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2012-10-26
Release date:2013-10-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.291 Å)
Cite:Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
4HR0
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BU of 4hr0 by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted metal cofactor
Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2012-10-26
Release date:2013-10-16
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.896 Å)
Cite:Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
6Q3A
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BU of 6q3a by Molmil
Apo form of Apolipoprotein N-acyltransferase (Lnt)
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Apolipoprotein N-acyltransferase, GLYCEROL
Authors:Wiseman, B, Hogbom, M.
Deposit date:2018-12-03
Release date:2019-12-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Conformational changes in Apolipoprotein N-acyltransferase (Lnt).
Sci Rep, 10, 2020
6QK2
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BU of 6qk2 by Molmil
R2-like ligand-binding oxidase Y715F mutant with anaerobically reconstituted Mn/Fe cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2019-01-28
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.596 Å)
Cite:Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein.
J.Am.Chem.Soc., 142, 2020
6QK0
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BU of 6qk0 by Molmil
R2-like ligand-binding oxidase E69D mutant with anaerobically reconstituted Mn/Fe cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2019-01-28
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein.
J.Am.Chem.Soc., 142, 2020
6QK1
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BU of 6qk1 by Molmil
R2-like ligand-binding oxidase Y175F mutant with aerobically reconstituted Mn/Fe cofactor
Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2019-01-28
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein.
J.Am.Chem.Soc., 142, 2020
6QJV
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BU of 6qjv by Molmil
R2-like ligand-binding oxidase E69D mutant with aerobically reconstituted Mn/Fe cofactor
Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2019-01-25
Release date:2020-02-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.905 Å)
Cite:Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein.
J.Am.Chem.Soc., 142, 2020
2RB4
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BU of 2rb4 by Molmil
Crystal structure of the Helicase domain of human DDX25 RNA helicase
Descriptor: ATP-dependent RNA helicase DDX25, CHLORIDE ION, SULFATE ION, ...
Authors:Lehtio, L, Hogbom, M, Uppenberg, J, Arrowsmith, C.H, Berglund, H, Edwards, A.M, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2007-09-18
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
2NZ2
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BU of 2nz2 by Molmil
Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline
Descriptor: ASPARTIC ACID, Argininosuccinate synthase, CITRULLINE, ...
Authors:Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2006-11-22
Release date:2006-12-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of human argininosuccinate synthetase.
Acta Crystallogr.,Sect.D, 64, 2008
6R81
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BU of 6r81 by Molmil
Multidrug resistance transporter BmrA mutant E504A bound with ATP and Mg solved by Cryo-EM
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION
Authors:Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P.
Deposit date:2019-03-30
Release date:2020-05-06
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Sci Adv, 8, 2022
5N77
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BU of 5n77 by Molmil
Crystal structure of the cytosolic domain of the CorA magnesium channel from Escherichia coli in complex with magnesium
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, MAGNESIUM ION, Magnesium transport protein CorA
Authors:Lerche, M, Sandhu, H, Flockner, L, Hogbom, M, Rapp, M.
Deposit date:2017-02-20
Release date:2017-07-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and Cooperativity of the Cytosolic Domain of the CorA Mg(2+) Channel from Escherichia coli.
Structure, 25, 2017
5N78
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BU of 5n78 by Molmil
Crystal structure of the cytosolic domain of the CorA Mg2+ channel from Escherichia coli in complex with magnesium and cobalt hexammine
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, COBALT HEXAMMINE(III), MAGNESIUM ION, ...
Authors:Lerche, M, Sandhu, H, Flockner, L, Hogbom, M, Rapp, M.
Deposit date:2017-02-20
Release date:2017-07-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure and Cooperativity of the Cytosolic Domain of the CorA Mg(2+) Channel from Escherichia coli.
Structure, 25, 2017
6GP2
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BU of 6gp2 by Molmil
Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, DOPA-active form
Descriptor: CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain
Authors:Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M.
Deposit date:2018-06-05
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens.
Nature, 563, 2018
6GP3
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BU of 6gp3 by Molmil
Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, inactive form
Descriptor: CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain
Authors:Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M.
Deposit date:2018-06-05
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens.
Nature, 563, 2018

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