7MLD
| PYL10 bound to the ABA pan-antagonist antabactin | Descriptor: | Abscisic acid receptor PYL10, CITRIC ACID, antabactin | Authors: | Peterson, F.C, Vaidya, A.S, Volkman, B.F, Cutler, S.R. | Deposit date: | 2021-04-28 | Release date: | 2021-09-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MWN
| An engineered PYL2-based WIN 55,212-2 synthetic cannabinoid sensor with a stabilized HAB1 variant | Descriptor: | ACETATE ION, Abscisic acid receptor PYL2, CHLORIDE ION, ... | Authors: | Peterson, F.C, Beltran, J, Bedewitz, M, Steiner, P.J, Cutler, S.R, Whitehead, T.A. | Deposit date: | 2021-05-17 | Release date: | 2022-06-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds. Nat.Biotechnol., 40, 2022
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5UR5
| PYR1 bound to the rationally designed agonist 4m | Descriptor: | Abscisic acid receptor PYR1, GLYCEROL, N-(4-cyano-3-ethyl-5-methylphenyl)-1-(4-methylphenyl)methanesulfonamide, ... | Authors: | Peterson, F.C, Vaidya, A, Jensen, D.R, Volkman, B.F, Cutler, S.R. | Deposit date: | 2017-02-09 | Release date: | 2017-11-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | A Rationally Designed Agonist Defines Subfamily IIIA Abscisic Acid Receptors As Critical Targets for Manipulating Transpiration. ACS Chem. Biol., 12, 2017
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5US5
| Solution structure of the IreB homodimer | Descriptor: | UPF0297 protein EF_1202 | Authors: | Lytle, B.L, Peterson, F.C, Volkman, B.F, Kristich, C.J, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2017-02-13 | Release date: | 2017-06-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and Dimerization of IreB, a Negative Regulator of Cephalosporin Resistance in Enterococcus faecalis. J. Mol. Biol., 429, 2017
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5UR4
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5WKA
| Crystal structure of a GH1 beta-glucosidase retrieved from microbial metagenome of Poraque Amazon lake | Descriptor: | Beta-glucosidase, DI(HYDROXYETHYL)ETHER, GLYCEROL | Authors: | Morais, M.A.B, Toyama, D, Ramos, F.C, Zanphorlin, L.M, Tonoli, C.C.C, Miranda, F.P, Ruller, R, Henrique-Silva, F, Murakami, M.T. | Deposit date: | 2017-07-24 | Release date: | 2018-03-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A novel beta-glucosidase isolated from the microbial metagenome of Lake Poraque (Amazon, Brazil). Biochim. Biophys. Acta, 1866, 2018
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1JF7
| HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH PNU177836 | Descriptor: | 5-(2-{2-[(TERT-BUTOXY-HYDROXY-METHYL)-AMINO]-1-HYDROXY-3-PHENYL-PROPYLAMINO}-3-HYDROXY-3-PENTYLAMINO-PROPYL)-2-CARBOXYMETHOXY-BENZOIC ACID, PROTEIN-TYROSINE PHOSPHATASE 1B | Authors: | Larsen, S.D, Barf, T, Liljebris, C, May, P.D, Ogg, D, O'Sullivan, T.J, Palazuk, B.J, Schostarez, H.J, Stevens, F.C, Bleasdale, J.E. | Deposit date: | 2001-06-20 | Release date: | 2002-02-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B. J.Med.Chem., 45, 2002
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1JMJ
| Crystal Structure of Native Heparin Cofactor II | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HEPARIN COFACTOR II, ... | Authors: | Baglin, T.P, Carrell, R.W, Church, F.C, Huntington, J.A. | Deposit date: | 2001-07-18 | Release date: | 2002-08-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism. Proc.Natl.Acad.Sci.USA, 99, 2002
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3DEU
| Crystal structure of transcription regulatory protein slyA from Salmonella typhimurium in complex with salicylate ligands | Descriptor: | 2-HYDROXYBENZOIC ACID, Transcriptional regulator slyA | Authors: | Le Trong, I, Brzovic, P.S, Fang, F.C, Libby, S.J, Stenkamp, R.E. | Deposit date: | 2008-06-10 | Release date: | 2008-06-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Evolution of SlyA/RovA Transcription Factors from Repressors to Countersilencers in Enterobacteriaceae . Mbio, 10, 2019
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1MKE
| Structure of the N-WASP EVH1 Domain-WIP complex | Descriptor: | Fusion protein consisting of Wiskott-Aldrich syndrome protein interacting protein (WIP), GSGSG linker, and Neural Wiskott-Aldrich syndrome protein (N-WASP) | Authors: | Volkman, B.F, Prehoda, K.E, Scott, J.A, Peterson, F.C, Lim, W.A. | Deposit date: | 2002-08-29 | Release date: | 2002-12-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the N-WASP EVH1 Domain-WIP Complex. Insight into the
Molecular Basis of Wiskott-Aldrich Syndrome. Cell(Cambridge,Mass.), 111, 2002
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1M5A
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1M02
| NMR Structure of PW2 Bound to SDS Micelles: A Tryptophan-rich Anticocidial Peptide Selected from Phage Display Libraries | Descriptor: | HIS-PRO-LEU-LYS-GLN-TYR-TRP-TRP-ARG-PRO-SER-ILE | Authors: | Tinoco, L.W, da Silva Jr, A, Leite, A, Valente, A.P, Almeida, F.C. | Deposit date: | 2002-06-11 | Release date: | 2002-08-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of PW2 bound to SDS micelles. A tryptophan-rich anticoccidial peptide selected from phage display libraries J.Biol.Chem., 277, 2002
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3HI8
| Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii | Descriptor: | Proliferating cell nuclear antigen PcnA | Authors: | Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R. | Deposit date: | 2009-05-19 | Release date: | 2009-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.202 Å) | Cite: | Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment. Acta Crystallogr.,Sect.D, 65, 2009
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3K41
| Crystal structure of sCD-MPR mutant E19Q/K137M bound to Man-6-P | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-beta-D-mannopyranose, Cation-dependent mannose-6-phosphate receptor, ... | Authors: | Olson, L.J, Sun, G, Bohnsack, R.N, Peterson, F.C, Dahms, N.M, Kim, J.J.P. | Deposit date: | 2009-10-05 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor. Biochemistry, 49, 2010
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3K43
| Crystal structure of sCD-MPR mutant E19Q/K137M pH 6.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Cation-dependent mannose-6-phosphate receptor, ... | Authors: | Olson, L.J, Sun, G, Bohnsack, R.N, Peterson, F.C, Dahms, N.M, Kim, J.J.P. | Deposit date: | 2009-10-05 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor. Biochemistry, 49, 2010
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3K42
| Crystal structure of sCD-MPR mutant E19Q/K137M pH 7.0 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-dependent mannose-6-phosphate receptor, SN-GLYCEROL-1-PHOSPHATE, ... | Authors: | Olson, L.J, Sun, G, Bohnsack, R.N, Peterson, F.C, Dahms, N.M, Kim, J.J.P. | Deposit date: | 2009-10-05 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor. Biochemistry, 49, 2010
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3LHR
| Crystal structure of the SCAN domain from Human ZNF24 | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ETHYL MERCURY ION, ... | Authors: | Volkman, B.F, Peterson, F.C, Bingman, C.A, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2010-01-22 | Release date: | 2010-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the SCAN domain from Human ZNF24 To be Published
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3NJ1
| X-ray crystal structure of the PYL2(V114I)-pyrabactin A complex | Descriptor: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL2, GLYCEROL, ... | Authors: | Peterson, F.C, Burgie, E.S, Bingman, C.A, Volkman, B.F, Phillips Jr, G.N, Cutler, S.R, Jensen, D.R, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2010-06-16 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Structural basis for selective activation of ABA receptors. Nat.Struct.Mol.Biol., 17, 2010
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7UWY
| NMR solution structure of the De novo designed small beta-barrel protein 29_bp_sh3 | Descriptor: | De novo designed small beta-barrel protein 29_bp_sh3 | Authors: | Peterson, F.C, Kim, D.E, Jensen, D.R, Saleem, A, Chow, C.M, Volkman, B.F, Baker, D. | Deposit date: | 2022-05-04 | Release date: | 2023-03-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | De novo design of small beta barrel proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
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7UWZ
| NMR solution structure of the De novo designed small beta-barrel protein 33_bp_sh3 | Descriptor: | De novo designed small beta-barrel protein 33_bp_sh3 | Authors: | Peterson, F.C, Kim, D.E, Jensen, D.R, Saleem, A, Chow, C.M, Volkman, B.F, Baker, D. | Deposit date: | 2022-05-04 | Release date: | 2023-03-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | De novo design of small beta barrel proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
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3NJO
| X-ray crystal structure of the Pyr1-pyrabactin A complex | Descriptor: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYR1, CHLORIDE ION, ... | Authors: | Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Peterson, F.C, Volkman, B.F, Cutler, S.R, Jensen, D.R, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2010-06-17 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.473 Å) | Cite: | Structural basis for selective activation of ABA receptors. Nat.Struct.Mol.Biol., 17, 2010
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3NJ0
| X-ray crystal structure of the PYL2-pyrabactin A complex | Descriptor: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL2, DI(HYDROXYETHYL)ETHER, ... | Authors: | Peterson, F.C, Burgie, E.S, Bingman, C.A, Volkman, B.F, Phillips Jr, G.N, Cutler, S.R, Jensen, D.R, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2010-06-16 | Release date: | 2010-08-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural basis for selective activation of ABA receptors. Nat.Struct.Mol.Biol., 17, 2010
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3T4N
| Structure of the regulatory fragment of Saccharomyces cerevisiae AMPK in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ... | Authors: | Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmdit, M.C, Gamblin, S.J, Carling, D. | Deposit date: | 2011-07-26 | Release date: | 2011-11-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase. Cell Metab, 14, 2011
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3TE5
| structure of the regulatory fragment of sacchromyces cerevisiae ampk in complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ... | Authors: | Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmidt, M.C, Gamblin, S.J, Carling, D. | Deposit date: | 2011-08-12 | Release date: | 2011-11-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase. Cell Metab, 14, 2011
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3QPZ
| Crystal structure of the N59A mutant of the 3-deoxy-d-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, GLYCEROL, ... | Authors: | Allison, T.M, Jameson, G.B, Parker, E.J, Cochrane, F.C. | Deposit date: | 2011-02-14 | Release date: | 2011-04-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase Biochemistry, 50, 2011
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