1JMJ

Crystal Structure of Native Heparin Cofactor II

Summary for 1JMJ

Related1JMO
DescriptorHEPARIN COFACTOR II, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... (5 entities in total)
Functional Keywordsserpin, thrombin inhibitor, heparin, blood clotting
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight110937.53
Authors
Baglin, T.P.,Carrell, R.W.,Church, F.C.,Huntington, J.A. (deposition date: 2001-07-18, release date: 2002-08-30, Last modification date: 2011-07-13)
Primary citation
Baglin, T.P.,Carrell, R.W.,Church, F.C.,Esmon, C.T.,Huntington, J.A.
Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism.
Proc.Natl.Acad.Sci.USA, 99:11079-11084, 2002
PubMed: 12169660 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.162232399
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.35 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.250140.3%5.5%14.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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