1JMO
Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex
Summary for 1JMO
Entry DOI | 10.2210/pdb1jmo/pdb |
Related | 1JMJ |
Descriptor | Thrombin, light chain, Thrombin, heavy chain, HEPARIN COFACTOR II, ... (8 entities in total) |
Functional Keywords | serpin, thrombin, protease, inhibition, inhibitor, blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 92073.03 |
Authors | Baglin, T.P.,Carrell, R.W.,Esmon, C.T.,Huntington, J.A. (deposition date: 2001-07-19, release date: 2002-08-30, Last modification date: 2024-04-03) |
Primary citation | Baglin, T.P.,Carrell, R.W.,Church, F.C.,Esmon, C.T.,Huntington, J.A. Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism. Proc.Natl.Acad.Sci.USA, 99:11079-11084, 2002 Cited by PubMed: 12169660DOI: 10.1073/pnas.162232399 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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