3K43

Crystal structure of sCD-MPR mutant E19Q/K137M pH 6.5

Summary for 3K43

• Entry DOI: 10.2210/pdb3k43/pdb
• Related: 3K41 3K42
• Descriptor: Cation-dependent mannose-6-phosphate receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (6 entities in total)
• Functional Keywords: transport, lysosome, mannose, receptor, sugar binding, glycoprotein, membrane, phosphoprotein, transmembrane, protein transport, sugar binding protein
• Biological source: Bos taurus (bovine,cow,domestic cattle,domestic cow)
• Cellular location: Lysosome membrane ; Single-pass type I membrane protein : P11456
• Total number of polymer chains: 2
• Total formula weight: 35747.96

Authors

Olson, L.J.,Sun, G.,Bohnsack, R.N.,Peterson, F.C.,Dahms, N.M.,Kim, J.J.P. (deposition date: 2009-10-05, release date: 2009-11-24, Last modification date: 2023-09-06)

• Primary citation: Olson, L.J.,Sun, G.,Bohnsack, R.N.,Peterson, F.C.,Dahms, N.M.,Kim, J.J.; Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor.; Biochemistry, 49:236-246, 2010; PubMed: 19928875; DOI: 10.1021/bi901725x

Experimental method

X-RAY DIFFRACTION (2 Å)