3K43
Crystal structure of sCD-MPR mutant E19Q/K137M pH 6.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cation-dependent mannose-6-phosphate receptor | polymer | 154 | 17444.6 | 2 | UniProt (P11456) Pfam (PF02157) | Bos taurus (bovine cow domestic cattle domestic cow) | CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46 |
| 2 | C, G (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | D, E, I (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | H (B) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 154 (UniProt: P11456)
| PDB | External Database | Details |
|---|---|---|
| Gln 19 | Glu 47 | engineered mutation |
| Gln 31 | Asn 59 | engineered mutation |
| Gln 57 | Asn 85 | engineered mutation |
| Gln 68 | Asn 96 | engineered mutation |
| Gln 87 | Asn 115 | engineered mutation |
| Met 137 | Lys 165 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34889.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 858.7 | |
| All* | Total formula weight | 35748.0 |
