3SVH
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![BU of 3svh by Molmil](/molmil-images/mine/3svh) | Crystal Structure of the bromdomain of human CREBBP in complex with a 3,5-dimethylisoxazol ligand | Descriptor: | 1,2-ETHANEDIOL, 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-ethoxybenzoic acid, CREB-binding protein | Authors: | Filippakopoulos, P, Picaud, S, Felletar, I, Hewings, S.D, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Conway, S.J, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2011-07-12 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the bromdomain of human CREBBP in complex with a 3,5-dimethylisoxazol ligand To be Published
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3SVF
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![BU of 3svf by Molmil](/molmil-images/mine/3svf) | Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand | Descriptor: | (4S)-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-(2-hydroxyethoxy)-3-methyl-3,4-dihydroquinazolin-2(1H)-one, Bromodomain-containing protein 4 | Authors: | Filippakopoulos, P, Picaud, S, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2011-07-12 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.975 Å) | Cite: | Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand TO BE PUBLISHED
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3RMU
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![BU of 3rmu by Molmil](/molmil-images/mine/3rmu) | Crystal structure of human Methylmalonyl-CoA epimerase, MCEE | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, Methylmalonyl-CoA epimerase, ... | Authors: | Chaikuad, A, Krysztofinska, E, Froese, D.S, Yue, W.W, Vollmar, M, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2011-04-21 | Release date: | 2011-05-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of human Methylmalonyl-CoA epimerase, MCEE To be Published
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2VWR
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![BU of 2vwr by Molmil](/molmil-images/mine/2vwr) | Crystal structure of the second pdz domain of numb-binding protein 2 | Descriptor: | LIGAND OF NUMB PROTEIN X 2 | Authors: | Roos, A.K, Guo, K, Burgess-Brown, N, Yue, W.W, Elkins, J.M, Pike, A.C.W, Filippakopoulos, P, Arrowsmith, C.H, Wikstom, M, Edwards, A, von Delft, F, Bountra, C, Doyle, D, Oppermann, U. | Deposit date: | 2008-06-26 | Release date: | 2008-09-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal Structure of the Second Pdz Domain of the Human Numb-Binding Protein 2 To be Published
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3S8I
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![BU of 3s8i by Molmil](/molmil-images/mine/3s8i) | The retroviral-like protease (RVP) domain of human DDI1 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | Authors: | Walker, J.R, Asinas, A, Dong, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2011-05-28 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Retropepsin-Like Domain of Human DDI1 To be Published
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3SMP
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![BU of 3smp by Molmil](/molmil-images/mine/3smp) | Monoclinic crystal structure of human pantothenate kinase 1 alpha | Descriptor: | ACETYL COENZYME *A, ARSENIC, CHLORIDE ION, ... | Authors: | Guan, X, Tempel, W, Hong, B, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2011-06-28 | Release date: | 2011-07-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Monoclinic crystal structure of human pantothenate kinase 1 alpha to be published
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3TLX
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![BU of 3tlx by Molmil](/molmil-images/mine/3tlx) | Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Wernimont, A.K, Loppnau, P, Crombet, L, Weadge, J, Perieteanu, A, Edwards, A.M, Arrowsmith, C.H, Park, H, Bountra, C, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2011-08-30 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum TO BE PUBLISHED
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3S92
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![BU of 3s92 by Molmil](/molmil-images/mine/3s92) | Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1 | Descriptor: | (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL, Bromodomain-containing protein 3 | Authors: | Filippakopoulos, P, Picaud, S, Qi, J, Keates, T, Felletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bradner, J.E, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2011-05-31 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1 To be Published
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2VSV
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![BU of 2vsv by Molmil](/molmil-images/mine/2vsv) | Crystal structure of the PDZ domain of human rhophilin-2 | Descriptor: | RHOPHILIN-2 | Authors: | Pike, A.C.W, Kochan, G, Sun, Z, Shafqat, N, Pilka, E.S, Roos, A, Elkins, J, Burgess-Brown, N, Murray, J.W, von Delft, F, Wikstrom, M, Edwards, A, Arrowsmith, C.H, Bountra, C, Oppermann, U. | Deposit date: | 2008-04-29 | Release date: | 2008-07-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal Structure of the Pdz Domain of Human Rhophilin-2 To be Published
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3SMT
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![BU of 3smt by Molmil](/molmil-images/mine/3smt) | Crystal structure of human SET domain-containing protein3 | Descriptor: | ACETATE ION, ARSENIC, Histone-lysine N-methyltransferase setd3, ... | Authors: | Dong, A, Zeng, H, Walker, J.R, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2011-06-28 | Release date: | 2011-07-20 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Crystal structure of human SET domain-containing protein3 To be Published
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2WNT
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![BU of 2wnt by Molmil](/molmil-images/mine/2wnt) | Crystal Structure of the Human Ribosomal protein S6 kinase | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, RIBOSOMAL PROTEIN S6 KINASE, ... | Authors: | Muniz, J.R.C, Elkins, J.M, Wang, J, Ugochukwu, E, Salah, E, King, O, Picaud, S, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S. | Deposit date: | 2009-07-20 | Release date: | 2009-08-25 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the Human Ribosomal Protein S6 Kinase To be Published
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2VN8
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![BU of 2vn8 by Molmil](/molmil-images/mine/2vn8) | Crystal structure of human Reticulon 4 interacting protein 1 in complex with NADPH | Descriptor: | CITRIC ACID, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Pike, A.C.W, Guo, K, Elkins, J, Ugochukwu, E, Roos, A.K, Filippakopoulos, P, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Oppermann, U. | Deposit date: | 2008-01-31 | Release date: | 2008-03-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Human Reticulon 4 Interacting Protein 1 in Complex with Nadph To be Published
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3QWE
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![BU of 3qwe by Molmil](/molmil-images/mine/3qwe) | Crystal structure of the N-terminal domain of the GEM interacting protein | Descriptor: | GEM-interacting protein, UNKNOWN ATOM OR ION | Authors: | Guan, X, Tempel, W, Tong, Y, Shen, L, Wang, H, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2011-02-28 | Release date: | 2011-03-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the N-terminal domain of the GEM interacting protein to be published
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3QWL
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![BU of 3qwl by Molmil](/molmil-images/mine/3qwl) | Crystal structure of human TBC1 domain family member 7 | Descriptor: | TBC1 domain family member 7, UNKNOWN ATOM OR ION | Authors: | Guan, X, Tempel, W, Tong, Y, Wernimont, A.K, Landry, R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2011-02-28 | Release date: | 2011-06-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of human TBC1 domain family member 7 to be published
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2XIO
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![BU of 2xio by Molmil](/molmil-images/mine/2xio) | Structure of putative deoxyribonuclease TATDN1 isoform a | Descriptor: | 1,2-ETHANEDIOL, NICKEL (II) ION, PUTATIVE DEOXYRIBONUCLEASE TATDN1, ... | Authors: | Muniz, J.R.C, Cocking, R, Puranik, S, Krojer, T, Raynor, J, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W, Kavanagh, K.L, Oppermann, U. | Deposit date: | 2010-06-30 | Release date: | 2010-07-14 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Structure of Putative Deoxyribonuclease Tatdn1 Isoform A To be Published
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3Q5I
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![BU of 3q5i by Molmil](/molmil-images/mine/3q5i) | Crystal Structure of PBANKA_031420 | Descriptor: | CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Wernimont, A.K, Hutchinson, A, Sullivan, H, Panico, E, Crombet, L, Cossar, D, Hassani, A, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Neculai, A.M, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2010-12-28 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of CDPK1 from Plasmodium Bergheii, PBANKA_031420 To be Published
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2VPH
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![BU of 2vph by Molmil](/molmil-images/mine/2vph) | Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain | Descriptor: | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 4 | Authors: | Roos, A.K, Wang, J, Burgess-Brown, N, Elkins, J.M, Kavanagh, K, Pike, A.C.W, Filippakopoulos, P, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Bountra, C, Knapp, S. | Deposit date: | 2008-02-29 | Release date: | 2008-03-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Human Protein Tyrosine Phosphatase, Non-Receptor Type 4, Pdz Domain To be Published
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2VPK
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![BU of 2vpk by Molmil](/molmil-images/mine/2vpk) | Crystal structure of the BTB domain of human myoneurin | Descriptor: | MYONEURIN | Authors: | Cooper, C.D.O, Murray, J.W, Bullock, A, Pike, A.C.W, von Delft, F, Filippakopoulos, P, Salah, E, Edwards, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Knapp, S. | Deposit date: | 2008-02-29 | Release date: | 2008-03-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Btb Domain of Human Myoneurin To be Published
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3S4Y
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![BU of 3s4y by Molmil](/molmil-images/mine/3s4y) | Crystal structure of human thiamin pyrophosphokinase 1 | Descriptor: | CALCIUM ION, SULFATE ION, THIAMINE DIPHOSPHATE, ... | Authors: | Shen, L, Tempel, W, Tong, Y, Li, Y, Walker, J.R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2011-05-20 | Release date: | 2011-06-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of human thiamin pyrophosphokinase 1 to be published
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3SN5
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![BU of 3sn5 by Molmil](/molmil-images/mine/3sn5) | Crystal structure of human CYP7A1 in complex with cholest-4-en-3-one | Descriptor: | (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, Cholesterol 7-alpha-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Strushkevich, N, Tempel, W, MacKenzie, F, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2011-06-28 | Release date: | 2011-07-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of human CYP7A1 in complex with cholest-4-en-3-one To be Published
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3S95
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![BU of 3s95 by Molmil](/molmil-images/mine/3s95) | Crystal structure of the human LIMK1 kinase domain in complex with staurosporine | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | Authors: | Beltrami, A, Chaikuad, A, Daga, N, Elkins, J.M, Mahajan, P, Savitsky, P, Vollmar, M, Krojer, T, Muniz, J.R.C, Fedorov, O, Allerston, C.K, Yue, W.W, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC) | Deposit date: | 2011-05-31 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of the human LIMK1 kinase domain in complex with staurosporine To be Published
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2WBI
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![BU of 2wbi by Molmil](/molmil-images/mine/2wbi) | Crystal structure of human acyl-CoA dehydrogenase 11 | Descriptor: | ACYL-COA DEHYDROGENASE FAMILY MEMBER 11, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, ... | Authors: | Muniz, J.R.C, Guo, K, Savitsky, P, Roos, A, Yue, W, Pilka, E, von Delft, F, Edwards, A.M, Bountra, C, Arrowsmith, C.H, Weigelt, J, Oppermann, U. | Deposit date: | 2009-02-28 | Release date: | 2009-05-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Human Acyl-Coa Dehydrogenase 11 To be Published
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3RBN
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![BU of 3rbn by Molmil](/molmil-images/mine/3rbn) | Crystal structure of MutL protein homolog 1 isoform 1 [Homo sapiens] | Descriptor: | DNA mismatch repair protein Mlh1 | Authors: | Dong, A, Dombrovsky, L, Wernimont, A, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2011-03-29 | Release date: | 2011-04-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of MutL protein homolog 1 isoform 1 [Homo sapiens] To be Published
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3SM9
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![BU of 3sm9 by Molmil](/molmil-images/mine/3sm9) | Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, CHLORIDE ION, Metabotropic glutamate receptor 3, ... | Authors: | Wernimont, A.K, Dong, A, Seitova, A, Crombet, L, Khutoreskaya, G, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Cossar, D, Dobrovetsky, E, Structural Genomics Consortium (SGC) | Deposit date: | 2011-06-27 | Release date: | 2011-07-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist TO BE PUBLISHED
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2XSN
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![BU of 2xsn by Molmil](/molmil-images/mine/2xsn) | Crystal Structure of Human Tyrosine Hydroxylase Catalytic Domain | Descriptor: | TYROSINE 3-MONOOXYGENASE, ZINC ION | Authors: | Muniz, J.R.C, Cooper, C.D.O, Yue, W.W, Krysztofinska, E, von Delft, F, Knapp, S, Gileadi, O, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Kavanagh, K.L, Oppermann, U. | Deposit date: | 2010-10-29 | Release date: | 2010-11-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Crystal Structure of Human Tyrosine Hydroxylase Catalytic Domain To be Published
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