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3CFD
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BU of 3cfd by Molmil
Purple-fluorescent antibody EP2-25C10 in complex with its stilbene hapten
Descriptor: 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, ...
Authors:Debler, E.W, Heine, A, Wilson, I.A.
Deposit date:2008-03-03
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
8ECZ
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BU of 8ecz by Molmil
Bovine Fab 4C1
Descriptor: 4C1 Fab heavy chain, 4C1 Fab light chain, PHOSPHATE ION
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ECQ
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BU of 8ecq by Molmil
Bovine Fab 2G3
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2G3 Fab Heavy chain, 2G3 Fab Light chain, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ED1
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BU of 8ed1 by Molmil
Bovine Fab 5C1
Descriptor: 5C1 Fab heavy chain, 5C1 Fab light chain, GLYCEROL, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EDF
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BU of 8edf by Molmil
Bovine Fab SKD in complex with Sars COV-2 receptor binding domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SKD Fab Light chain, SKD Fab heavy chain, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-04
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
6WJ1
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BU of 6wj1 by Molmil
Crystal structure of Fab 54-4H03 bound to H1 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 54-4H03 heavy chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2020-04-11
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
8ECV
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BU of 8ecv by Molmil
Bovine Fab 2F12
Descriptor: 2F12 Fab Heavy chain, 2F12 Fab Light chain
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
6WO4
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BU of 6wo4 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody HC11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2020-04-24
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
2JP9
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BU of 2jp9 by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
Descriptor: DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DGP*DCP*DGP*DC)-3'), DNA (5'-D(P*DGP*DCP*DGP*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), Wilms tumor 1, ...
Authors:Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
Deposit date:2007-04-30
Release date:2007-10-30
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
8ELO
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BU of 8elo by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-225
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 Fab heavy chain, CC12.1 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2022-09-26
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ELP
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BU of 8elp by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-240
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 Fab heavy chain, CC12.1 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2022-09-26
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc.Natl.Acad.Sci.USA, 120, 2023
6WOQ
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BU of 6woq by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2020-04-25
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.667 Å)
Cite:An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
8ELQ
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BU of 8elq by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-255
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 Fab heavy chain, CC12.1 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2022-09-26
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc.Natl.Acad.Sci.USA, 120, 2023
3LZG
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BU of 3lzg by Molmil
Crystal structure of a 2009 H1N1 influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2010-03-01
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010
6W41
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BU of 6w41 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody CR3022
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 Fab heavy chain, CR3022 Fab light chain, ...
Authors:Yuan, M, Wu, N.C, Zhu, X.Y, Wilson, I.A.
Deposit date:2020-03-09
Release date:2020-03-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.084 Å)
Cite:A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV.
Science, 368, 2020
3MJ8
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BU of 3mj8 by Molmil
Crystal structure of HL4E10 Fab, a hamster Ab stimulatory for gammadelta T cells
Descriptor: STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB LIGHT CHAIN
Authors:Verdino, P, Wilson, I.A.
Deposit date:2010-04-12
Release date:2011-04-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for gammadelta T cells.
Plos One, 6, 2011
3MBE
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BU of 3mbe by Molmil
TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II H2-IAg7 ALPHA CHAIN, ...
Authors:Corper, A.L, Yoshida, K, Teyton, L, Wilson, I.A.
Deposit date:2010-03-25
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.886 Å)
Cite:The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.
J.Clin.Invest., 120, 2010
6WCR
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BU of 6wcr by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule F0045(S)
Descriptor: (2,4-dichlorophenyl)[(2S)-2-phenylmorpholin-4-yl]methanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:kadam, R.U, Wilson, I.A.
Deposit date:2020-03-31
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WO5
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BU of 6wo5 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody 212.1.1 and non neutralizing antibody E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2020-04-24
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.619 Å)
Cite:An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
3CN4
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BU of 3cn4 by Molmil
Human transthyretin (TTR) in complex with N-(3,5-Dibromo-4-hydroxyphenyl)benzamide
Descriptor: N-(3,5-dibromo-4-hydroxyphenyl)benzamide, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2008-03-24
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3O2W
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BU of 3o2w by Molmil
Crystal structure of the 1E9 PheL89Ser/LeuH47Trp/MetH100bPhe Fab in complex with a 39A11 transition state analog
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CITRATE ANION, Chimeric antibody Fab 1E9, ...
Authors:Verdino, P, Wilson, I.A.
Deposit date:2010-07-22
Release date:2011-07-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of the 1E9 PheL89Ser/LeuH47Trp/MetH100bPhe Fab in complex with a 39A11 transition state analog
To be Published
6WIY
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BU of 6wiy by Molmil
Crystal structure of Fab 54-1G05
Descriptor: Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, GLYCEROL
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2020-04-11
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6X1V
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BU of 6x1v by Molmil
Structure of pHis Fab (SC44-8) in complex with pHis mimetic peptide
Descriptor: 1,2-ETHANEDIOL, ACLYana-3-pTza peptide, SC44-8 Heavy chain, ...
Authors:Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T.
Deposit date:2020-05-19
Release date:2021-02-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
3OB0
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BU of 3ob0 by Molmil
A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity
Descriptor: 7-deoxy-L-glycero-alpha-D-manno-heptopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, Fab 2G12, heavy chain, ...
Authors:Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G.
Deposit date:2010-08-06
Release date:2011-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
Proc.Natl.Acad.Sci.USA, 107, 2010
8EKF
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BU of 8ekf by Molmil
X-ray crystal structure of 311R Fab in complex with the PfCSP peptide NPNA-3
Descriptor: 311R Heavy Chain, 311R Light Chain, PfCSP peptide NPNA-3
Authors:Moskovitz, R, Wilson, I.A.
Deposit date:2022-09-20
Release date:2022-10-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023

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