7FAS
| VAR2CSA 3D7 ectodomain core region | Descriptor: | Erythrocyte membrane protein 1, PfEMP1 | Authors: | Wang, L, Zhaoning, W. | Deposit date: | 2021-07-07 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum. Cell Discov, 7, 2021
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6KE4
| ABloop reengineered Ferritin Nanocage | Descriptor: | CALCIUM ION, CHLORIDE ION, FE (III) ION, ... | Authors: | Wang, W.M, Wang, H.F. | Deposit date: | 2019-07-03 | Release date: | 2019-10-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | AB loop engineered ferritin nanocages for drug loading under benign experimental conditions. Chem.Commun.(Camb.), 55, 2019
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6KE2
| ABloop reengineered Ferritin Nanocage | Descriptor: | CALCIUM ION, CHLORIDE ION, FE (III) ION, ... | Authors: | Wang, W.M, Wang, H.F. | Deposit date: | 2019-07-03 | Release date: | 2019-10-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | AB loop engineered ferritin nanocages for drug loading under benign experimental conditions. Chem.Commun.(Camb.), 55, 2019
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3SWW
| Crystal structure of human dpp-iv in complex with sa-(+)-3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)- 2-methyl-5h-pyrrolo[3,4-b]pyridin-7(6h)-one | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyethyl)-2-methyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one, ... | Authors: | Klei, H.E. | Deposit date: | 2011-07-14 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site. Bioorg.Med.Chem.Lett., 21, 2011
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4EFG
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4EDE
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4EEJ
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4EXZ
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7FAP
| Structure of VAR2CSA-CSA 3D7 | Descriptor: | 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Erythrocyte membrane protein 1, PfEMP1 | Authors: | Wang, L, Wang, Z. | Deposit date: | 2021-07-07 | Release date: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum. Cell Discov, 7, 2021
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7DWN
| Crystal structure of Vibrio fischeri DarR in complex with DNA reveals the transcriptional activation mechanism of LTTR family members | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Predicted DNA-binding transcriptional regulator | Authors: | Wang, W.W, Wu, H, He, J.H, Yu, F. | Deposit date: | 2021-01-17 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism. Int.J.Biol.Macromol., 183, 2021
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7DWO
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7WRG
| Crystal structure of full-length kinesin-3 KLP-6 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein, MAGNESIUM ION | Authors: | Wang, W.J, Ren, J.Q, Song, W.Y, Feng, W. | Deposit date: | 2022-01-26 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition. Nat Commun, 13, 2022
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7XZ4
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8CO6
| Subtomogram average of Immature Rotavirus TLP penton | Descriptor: | Inner capsid protein VP2, Intermediate capsid protein VP6, Outer capsid glycoprotein VP7, ... | Authors: | Shah, P.N.M, Stuart, D.I. | Deposit date: | 2023-02-27 | Release date: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography. Cell Host Microbe, 31, 2023
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6Z5L
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8X5D
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5IJO
| Alternative composite structure of the inner ring of the human nuclear pore complex (16 copies of Nup188, 16 copies of Nup205) | Descriptor: | Nuclear pore complex protein Nup155, Nuclear pore complex protein Nup205, Nuclear pore complex protein Nup93, ... | Authors: | Kosinski, J, Mosalaganti, S, von Appen, A, Beck, M. | Deposit date: | 2016-03-02 | Release date: | 2016-04-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (21.4 Å) | Cite: | Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Science, 352, 2016
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7U6F
| Mouse retromer (VPS26/VPS35/VPS29) heterotrimers | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... | Authors: | Kendall, A.K, Chandra, M, Jackson, L.P. | Deposit date: | 2022-03-04 | Release date: | 2022-10-12 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Improved mammalian retromer cryo-EM structures reveal a new assembly interface. J.Biol.Chem., 298, 2022
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5IJN
| Composite structure of the inner ring of the human nuclear pore complex (32 copies of Nup205) | Descriptor: | NUCLEAR PORE COMPLEX PROTEIN NUP155, NUCLEAR PORE COMPLEX PROTEIN NUP205, NUCLEAR PORE COMPLEX PROTEIN NUP54, ... | Authors: | Kosinski, J, Mosalaganti, S, von Appen, A, Beck, M. | Deposit date: | 2016-03-02 | Release date: | 2016-04-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (21.4 Å) | Cite: | Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Science, 352, 2016
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8BP8
| SPA of Trypsin untreated Rotavirus TLP spike | Descriptor: | CALCIUM ION, Inner capsid protein VP2, Intermediate capsid protein VP6, ... | Authors: | Shah, P.N.M, Stuart, D.I. | Deposit date: | 2022-11-16 | Release date: | 2023-04-05 | Last modified: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography. Cell Host Microbe, 31, 2023
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8COA
| in situ Subtomogram average of Immature Rotavirus TLP spike | Descriptor: | Intermediate capsid protein VP6, Outer capsid glycoprotein VP7, Outer capsid protein VP4 | Authors: | Shah, P.N.M, Stuart, D.I. | Deposit date: | 2023-02-27 | Release date: | 2023-04-05 | Last modified: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography. Cell Host Microbe, 31, 2023
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2N0A
| Atomic-resolution structure of alpha-synuclein fibrils | Descriptor: | Alpha-synuclein | Authors: | Tuttle, M.D, Comellas, G, Nieuwkoop, A.J, Covell, D.J, Berthold, D.A, Kloepper, K.D, Courtney, J.M, Kim, J.K, Schwieters, C.D, Lee, V.M, George, J.M, Rienstra, C.M. | Deposit date: | 2015-03-04 | Release date: | 2016-03-23 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Solid-state NMR structure of a pathogenic fibril of full-length human alpha-synuclein. Nat.Struct.Mol.Biol., 23, 2016
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7VMU
| Crystal Structure of SARS-CoV Spike Receptor-Binding Domain Complexed with Neutralizing Antibody | Descriptor: | Spike protein S1, scFv E4 | Authors: | Guo, Y, Wang, W, Jiao, P, Yang, H, Rao, Z, Cheng, G. | Deposit date: | 2021-10-09 | Release date: | 2021-11-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Antibody engineering improves neutralization activity against K417 spike mutant SARS-CoV-2 variants. Cell Biosci, 12, 2022
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4ZR2
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4UT6
| Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 B7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7, ... | Authors: | Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A. | Deposit date: | 2014-07-18 | Release date: | 2015-01-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses. Nature, 520, 2015
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