8K4C
| Crystal structure of PDE4D complexed with ethaverine hydrochloride | Descriptor: | 1,2-ETHANEDIOL, 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline, MAGNESIUM ION, ... | Authors: | Liu, J.Y, Li, M.J, Xu, Y.C. | Deposit date: | 2023-07-17 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors. Eur.J.Med.Chem., 262, 2023
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7Y04
| Hsp90-AhR-p23 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Aryl hydrocarbon receptor, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | Deposit date: | 2022-06-03 | Release date: | 2023-01-04 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
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7WP6
| Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 36H6 heavy chain, ... | Authors: | Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N. | Deposit date: | 2022-01-23 | Release date: | 2023-03-01 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine. Cell Host Microbe, 30, 2022
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7WP8
| Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 heavy chain, ... | Authors: | Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N. | Deposit date: | 2022-01-23 | Release date: | 2023-03-08 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine. Cell Host Microbe, 30, 2022
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8HPV
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8HP9
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8HPQ
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8ILF
| The crystal structure of dGTPalphaSe-Sp:DNApre-II:Pol X substrate ternary complex | Descriptor: | DNA (5'-D(*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), MANGANESE (II) ION, Repair DNA polymerase X, ... | Authors: | Qin, T, Zhao, Q.W, Gan, J.H, Huang, Z. | Deposit date: | 2023-03-03 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom. Int J Mol Sci, 24, 2023
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8IXE
| GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin seam region | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | Deposit date: | 2023-03-31 | Release date: | 2023-08-16 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
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8IXB
| GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin seam region | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | Deposit date: | 2023-03-31 | Release date: | 2023-08-16 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
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8IXA
| GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin non-seam region | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | Deposit date: | 2023-03-31 | Release date: | 2023-08-16 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
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8IXG
| GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin seam region | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | Deposit date: | 2023-03-31 | Release date: | 2023-08-16 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
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8IXD
| GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin non-seam region | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | Deposit date: | 2023-03-31 | Release date: | 2023-08-16 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
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8IXF
| GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin non-seam region | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. | Deposit date: | 2023-03-31 | Release date: | 2023-08-16 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
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7V49
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7X84
| Cryo-EM structure of the TMEM106B fibril from Parkinson's disease dementia | Descriptor: | Transmembrane protein 106B | Authors: | Zhao, Q.Y, Xia, W.C, Fan, Y, Sun, Y.P, Tao, Y.Q, Liu, C. | Deposit date: | 2022-03-11 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders. Cell Res., 32, 2022
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7XO3
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7XO1
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7XO2
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7XO0
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7V48
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7V47
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7X83
| Cryo-EM structure of the TMEM106B fibril from normal elder | Descriptor: | Transmembrane protein 106B | Authors: | Xia, W.C, Zhao, Q.Y, Fan, Y, Sun, Y.P, Tao, Y.Q, Liu, C. | Deposit date: | 2022-03-11 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders. Cell Res., 32, 2022
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7W9N
| THE STRUCTURE OF OBA33-OTA COMPLEX | Descriptor: | (2~{S})-2-[[(3~{R})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid, OTA DNA APTAMER (33-MER) | Authors: | Xu, G.H, Li, C.G. | Deposit date: | 2021-12-10 | Release date: | 2022-01-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Insights into the Mechanism of High-Affinity Binding of Ochratoxin A by a DNA Aptamer. J.Am.Chem.Soc., 144, 2022
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8IF5
| AFB1-AF26 APTAMER COMPLEX | Descriptor: | AFB1 DNA aptamer (26-MER), AFLATOXIN B1 | Authors: | Xu, G.H, Wang, C, Li, C.G. | Deposit date: | 2023-02-17 | Release date: | 2023-07-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis for high-affinity recognition of aflatoxin B1 by a DNA aptamer. Nucleic Acids Res., 51, 2023
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