1YH5
 
 | | Solution NMR Structure of Protein yggU from Escherichia coli. Northeast Structural Genomics Consortium Target ER14. | | Descriptor: | ORF, HYPOTHETICAL PROTEIN | | Authors: | Aramini, J.M, Xiao, R, Huang, Y.J, Acton, T.B, Wu, M.J, Mills, J.L, Tejero, R.T, Szyperski, T, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2005-01-06 | | Release date: | 2005-02-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Hypothetical Protein Yggu from E. Coli. Northeast Structural Genomics Consortium Target Er14.
To be Published
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1Y6U
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2AZL
 | | Crystal structure for the mutant F117E of Thermotoga maritima octaprenyl pyrophosphate synthase | | Descriptor: | octoprenyl-diphosphate synthase | | Authors: | Sun, H.Y, Ko, T.P, Kuo, C.J, Guo, R.T, Chou, C.C, Liang, P.H, Wang, A.H. | | Deposit date: | 2005-09-12 | | Release date: | 2006-03-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures
J.Bacteriol., 187, 2005
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1X6Q
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2JMF
 | | Solution structure of the Su(dx) WW4- Notch PY peptide complex | | Descriptor: | E3 ubiquitin-protein ligase suppressor of deltex, Neurogenic locus Notch protein | | Authors: | Avis, J.M, Blankley, R.T, Jennings, M.D, Golovanov, A.P. | | Deposit date: | 2006-11-05 | | Release date: | 2007-08-28 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Specificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of Deltex
J.Biol.Chem., 282, 2007
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2B57
 | | Guanine Riboswitch C74U mutant bound to 2,6-diaminopurine | | Descriptor: | 65-MER, 9H-PURINE-2,6-DIAMINE, ACETATE ION, ... | | Authors: | Gilbert, S.D, Stoddard, C.D, Wise, S.J, Batey, R.T. | | Deposit date: | 2005-09-27 | | Release date: | 2006-05-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain.
J.Mol.Biol., 359, 2006
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2ALE
 | | Crystal structure of yeast RNA splicing factor Snu13p | | Descriptor: | MAGNESIUM ION, NHP2/L7aE family protein YEL026W | | Authors: | Dobbyn, H.C, McEwan, P.A, Bella, J, O'Keefe, R.T. | | Deposit date: | 2005-08-05 | | Release date: | 2006-10-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants.
Biochem.Biophys.Res.Commun., 360, 2007
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2AO6
 | | Crystal structure of the human androgen receptor ligand binding domain bound with TIF2(iii) 740-753 peptide and R1881 | | Descriptor: | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE, 14-mer fragment of Nuclear receptor coactivator 2, androgen receptor | | Authors: | He, B, Gampe Jr, R.T, Kole, A.J, Hnat, A.T, Stanley, T.B, An, G, Stewart, E.L, Kalman, R.I, Minges, J.T, Wilson, E.M. | | Deposit date: | 2005-08-12 | | Release date: | 2005-08-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance
Mol.Cell, 16, 2004
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2AVU
 | | Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription | | Descriptor: | Flagellar transcriptional activator flhC, Transcriptional activator flhD, ZINC ION | | Authors: | Wang, S, Fleming, R.T, Westbrook, E.M, Matsumura, P, McKay, D.B. | | Deposit date: | 2005-08-30 | | Release date: | 2005-12-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the Escherichia coli FlhDC Complex, a Prokaryotic Heteromeric Regulator of Transcription.
J.Mol.Biol., 355, 2006
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2LN7
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2LA0
 | | Trn- peptide of the two-component bacteriocin Thuricin CD | | Descriptor: | Uncharacterized protein | | Authors: | Sit, C.S, Mckay, R.T, Hill, C, Ross, R.P, Vederas, J.C. | | Deposit date: | 2011-02-27 | | Release date: | 2012-01-11 | | Last modified: | 2018-08-22 | | Method: | SOLUTION NMR | | Cite: | The 3D structure of thuricin CD, a two-component bacteriocin with cysteine sulfur to alpha-carbon cross-links.
J.Am.Chem.Soc., 133, 2011
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1Z64
 | | NMR Solution Structure of Pleurocidin in DPC Micelles | | Descriptor: | Pleruocidin | | Authors: | Syvitski, R.T, Burton, I, Mattatall, N.R, Douglas, S.E, Jakeman, D.L. | | Deposit date: | 2005-03-21 | | Release date: | 2005-04-12 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Structural characterization of the antimicrobial peptide pleurocidin from winter flounder.
Biochemistry, 44, 2005
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1Z7X
 | | X-ray structure of human ribonuclease inhibitor complexed with ribonuclease I | | Descriptor: | CITRIC ACID, Ribonuclease I, Ribonuclease inhibitor | | Authors: | McCoy, J.G, Johnson, R.J, Raines, R.T, Bitto, E, Bingman, C.A, Wesenberg, G.E, Allard, S.T.M, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2005-03-28 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.
J.Mol.Biol., 368, 2007
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1ZJR
 | | Crystal Structure of A. aeolicus TrmH/SpoU tRNA modifying enzyme | | Descriptor: | GLYCEROL, SULFATE ION, tRNA (Guanosine-2'-O-)-methyltransferase | | Authors: | Pleshe, E, Truesdell, J, Batey, R.T. | | Deposit date: | 2005-04-30 | | Release date: | 2005-08-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus.
Acta Crystallogr.,Sect.F, 61, 2005
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2BB8
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2BKQ
 | | NEDD8 protease | | Descriptor: | SENTRIN-SPECIFIC PROTEASE 8 | | Authors: | Shen, L.N, Liu, H, Dong, C, Xirodimas, D, Naismith, J.H, Hay, R.T. | | Deposit date: | 2005-02-18 | | Release date: | 2005-02-21 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis of Nedd8 Ubiquitin Discrimination by the Deneddylating Enzyme Nedp1
Embo J., 24, 2005
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2BKR
 | | NEDD8 NEDP1 complex | | Descriptor: | NEDDYLIN, SENTRIN-SPECIFIC PROTEASE 8 | | Authors: | Shen, L.N, Liu, H, Dong, C, Xirodimas, D, Naismith, J.H, Hay, R.T. | | Deposit date: | 2005-02-18 | | Release date: | 2005-09-15 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis of Nedd8 Ubiquitin Discrimination by the Deneddylating Enzyme Nedp1
Embo J., 24, 2005
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2BMB
 | | X-ray structure of the bifunctional 6-hydroxymethyl-7,8- dihydroxypterin pyrophosphokinase dihydropteroate synthase from Saccharomyces cerevisiae | | Descriptor: | FOLIC ACID SYNTHESIS PROTEIN FOL1, PTERIN-6-YL-METHYL-MONOPHOSPHATE | | Authors: | Lawrence, M.C, Iliades, P, Fernley, R.T, Berglez, J, Pilling, P.A, Macreadie, I.G. | | Deposit date: | 2005-03-11 | | Release date: | 2006-01-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Three-Dimensional Structure of the Bifunctional 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase/Dihydropteroate Synthase of Saccharomyces Cerevisiae
J.Mol.Biol., 348, 2005
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2KID
 | | Solution Structure of the S. Aureus Sortase A-substrate Complex | | Descriptor: | (PHQ)LPA(B27) peptide, CALCIUM ION, Sortase | | Authors: | Suree, N, Liew, C.K, Villareal, V.A, Thieu, W, Fadeev, E.A, Clemens, J.J, Jung, M.E, Clubb, R.T. | | Deposit date: | 2009-05-01 | | Release date: | 2009-07-21 | | Last modified: | 2023-11-15 | | Method: | SOLUTION NMR | | Cite: | The structure of the Staphylococcus aureus sortase-substrate complex reveals how the universally conserved LPXTG sorting signal is recognized.
J.Biol.Chem., 284, 2009
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2M60
 | | Enterocin 7B | | Descriptor: | Enterocin JSB | | Authors: | Lohans, C.T, Towle, K.M, Miskolzie, M, McKay, R.T, van Belkum, M.J, McMullen, L.M, Vederas, J.C. | | Deposit date: | 2013-03-18 | | Release date: | 2013-06-12 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Solution Structures of the Linear Leaderless Bacteriocins Enterocin 7A and 7B Resemble Carnocyclin A, a Circular Antimicrobial Peptide
Biochemistry, 52, 2013
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2M5Z
 | | Enterocin 7A | | Descriptor: | Enterocin JSA | | Authors: | Lohans, C.T, Towle, K.M, Miskolzie, M, McKay, R.T, van Belkum, M.J, McMullen, L.M, Vederas, J.C. | | Deposit date: | 2013-03-16 | | Release date: | 2013-06-12 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Solution Structures of the Linear Leaderless Bacteriocins Enterocin 7A and 7B Resemble Carnocyclin A, a Circular Antimicrobial Peptide
Biochemistry, 52, 2013
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2MP2
 | | Solution structure of SUMO dimer in complex with SIM2-3 from RNF4 | | Descriptor: | E3 ubiquitin-protein ligase RNF4, Small ubiquitin-related modifier 3 | | Authors: | Xu, Y, Plechanovov, A, Simpson, P, Marchant, J, Leidecker, O, Sebastian, K, Hay, R.T, Matthews, S.J. | | Deposit date: | 2014-05-09 | | Release date: | 2014-07-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4.
Nat Commun, 5, 2014
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2NPF
 | | Structure of eEF2 in complex with moriniafungin | | Descriptor: | (1S,4R,5R,9S,11S)-2-({[(2S,5R,6R,7R,9S,10R)-2-(7-CARBOXYHEPTYL)-6-HYDROXY-10-METHOXY-9-METHYL-3-OXO-1,4,8-TRIOXASPIRO[4 .5]DEC-7-YL]OXY}METHYL)-9-FORMYL-13-ISOPROPYL-5-METHYLTETRACYCLO[7.4.0.02,11.04.8]TRIDEC-12-ENE-1-CARBOXYLIC ACID, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Soe, R, Mosley, R.T, Andersen, G.R. | | Deposit date: | 2006-10-27 | | Release date: | 2006-11-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2
J.Biol.Chem., 282, 2007
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2OH4
 | | Crystal structure of Vegfr2 with a benzimidazole-urea inhibitor | | Descriptor: | METHYL (5-{4-[({[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-1H-BENZIMIDAZOL-2-YL)CARBAMATE, SULFATE ION, Vascular endothelial growth factor receptor 2 | | Authors: | Nolte, R.T, Wang, L. | | Deposit date: | 2007-01-09 | | Release date: | 2007-09-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Discovery of Novel Benzimidazoles as Potent Inhibitors of TIE-2 and VEGFR-2 Tyrosine Kinase Receptors.
J.Med.Chem., 50, 2007
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2POB
 | | PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709 | | Descriptor: | GLYCEROL, N-[(2S)-2-[(2-BENZOYLPHENYL)AMINO]-3-{4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL}PROPYL]ACETAMIDE, Peroxisome proliferator-activated receptor gamma | | Authors: | Nolte, R.T. | | Deposit date: | 2007-04-26 | | Release date: | 2008-03-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Cocrystal structure guided array synthesis of PPARgamma inverse agonists
BIOORG.MED.CHEM.LETT., 17, 2007
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