3PDV
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5TSB
| Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Cd2+ | Descriptor: | CADMIUM ION, Membrane protein | Authors: | Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J. | Deposit date: | 2016-10-28 | Release date: | 2017-09-20 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway. Sci Adv, 3, 2017
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7YSX
| Crystal structure of PDE4D complexed with licoisoflavone A | Descriptor: | 1,2-ETHANEDIOL, 3-[3-(3-methylbut-2-enyl)-2,4-bis(oxidanyl)phenyl]-5,7-bis(oxidanyl)chromen-4-one, MAGNESIUM ION, ... | Authors: | Liu, J.Y, Li, M.J, Xu, Y.C. | Deposit date: | 2022-08-13 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19. Proc.Natl.Acad.Sci.USA, 120, 2023
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7YQF
| Crystal structure of PDE4D complexed with glycyrrhisoflavone | Descriptor: | 1,2-ETHANEDIOL, 3-[3-(3-methylbut-2-enyl)-4,5-bis(oxidanyl)phenyl]-5,7-bis(oxidanyl)chromen-4-one, MAGNESIUM ION, ... | Authors: | Liu, J.Y, Li, M.J, Xu, Y.C. | Deposit date: | 2022-08-06 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19. Proc.Natl.Acad.Sci.USA, 120, 2023
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5TSA
| Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Zn2+ | Descriptor: | CADMIUM ION, Membrane protein, ZINC ION | Authors: | Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J. | Deposit date: | 2016-10-28 | Release date: | 2017-09-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway. Sci Adv, 3, 2017
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3FM9
| Analysis of the Structural Determinants Underlying Discrimination between Substrate and Solvent in beta-Phosphoglucomutase Catalysis | Descriptor: | Beta-phosphoglucomutase, MAGNESIUM ION | Authors: | Finci, L, Lahiri, S, Peisach, E, Allen, K.N. | Deposit date: | 2008-12-19 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis. Biochemistry, 48, 2009
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8CS7
| [CCG/CCG] Self-Assembled 3D DNA Hexagonal Tensegrity Triangle | Descriptor: | DNA (5'-D(*CP*CP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*CP*CP*GP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), ... | Authors: | Lu, B, Vecchioni, S, Ohayon, Y.P, Seeman, N.C, Mao, C, Sha, R. | Deposit date: | 2022-05-12 | Release date: | 2022-12-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (6.67 Å) | Cite: | Programmable 3D Hexagonal Geometry of DNA Tensegrity Triangles. Angew.Chem.Int.Ed.Engl., 62, 2023
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8CS2
| [(1AP)G/TC] Self-Assembled 3D DNA Hexagonal Tensegrity Triangle | Descriptor: | DNA (5'-D(*(1AP)P*GP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), ... | Authors: | Lu, B, Vecchioni, S, Ohayon, Y.P, Seeman, N.C, Mao, C, Sha, R. | Deposit date: | 2022-05-12 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (6 Å) | Cite: | Programmable 3D Hexagonal Geometry of DNA Tensegrity Triangles. Angew.Chem.Int.Ed.Engl., 62, 2023
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8CS1
| [GA/CT] Self-Assembled 3D DNA Hexagonal Tensegrity Triangle | Descriptor: | DNA (5'-D(*CP*TP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), ... | Authors: | Lu, B, Vecchioni, S, Ohayon, Y.P, Seeman, N.C, Mao, C, Sha, R. | Deposit date: | 2022-05-12 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (4.56 Å) | Cite: | Programmable 3D Hexagonal Geometry of DNA Tensegrity Triangles. Angew.Chem.Int.Ed.Engl., 62, 2023
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8CS6
| [AGG/CTC] Self-Assembled 3D DNA Hexagonal Tensegrity Triangle | Descriptor: | DNA (5'-D(*AP*GP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*CP*TP*CP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), ... | Authors: | Lu, B, Vecchioni, S, Ohayon, Y.P, Seeman, N.C, Mao, C, Sha, R. | Deposit date: | 2022-05-12 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (6.76 Å) | Cite: | Programmable 3D Hexagonal Geometry of DNA Tensegrity Triangles. Angew.Chem.Int.Ed.Engl., 62, 2023
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8CYM
| [2T7+9bp Linker] Self-Assembled 3D DNA Hexagonal Tensegrity Triangle with 9 bp Sticky-End Linker | Descriptor: | DNA (5'-D(*AP*CP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*C)-3'), DNA (5'-D(*GP*AP*TP*GP*CP*GP*AP*GP*T)-3'), DNA (5'-D(*GP*TP*AP*CP*TP*CP*GP*CP*A)-3'), ... | Authors: | Lu, B, Vecchioni, S, Ohayon, Y.P, Seeman, N.C, Mao, C, Sha, R. | Deposit date: | 2022-05-24 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (7.76 Å) | Cite: | Programmable 3D Hexagonal Geometry of DNA Tensegrity Triangles. Angew.Chem.Int.Ed.Engl., 62, 2023
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8DAG
| [8 bp center] Self-Assembled 3D DNA Hexagonal Tensegrity Triangle | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*TP*GP*TP*GP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*CP*CP*GP*TP*CP*AP*CP*A)-3'), ... | Authors: | Lu, B, Vecchioni, S, Ohayon, Y.P, Seeman, N.C, Mao, C, Sha, R. | Deposit date: | 2022-06-13 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (6.16 Å) | Cite: | Programmable 3D Hexagonal Geometry of DNA Tensegrity Triangles. Angew.Chem.Int.Ed.Engl., 62, 2023
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8DAH
| [20 bp edge] Self-Assembled 3D DNA Hexagonal Tensegrity Triangle | Descriptor: | DNA (5'-D(*CP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), ... | Authors: | Lu, B, Vecchioni, S, Ohayon, Y.P, Seeman, N.C, Mao, C, Sha, R. | Deposit date: | 2022-06-13 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (5.47 Å) | Cite: | Programmable 3D Hexagonal Geometry of DNA Tensegrity Triangles. Angew.Chem.Int.Ed.Engl., 62, 2023
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8DCJ
| [A:T] Self-Assembled 3D DNA Rhombohedral Tensegrity Triangle | Descriptor: | DNA (5'-D(*AP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*TP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), ... | Authors: | Lu, B, Vecchioni, S, Ohayon, Y.P, Seeman, N.C, Mao, C, Sha, R. | Deposit date: | 2022-06-16 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | Programmable 3D Hexagonal Geometry of DNA Tensegrity Triangles. Angew.Chem.Int.Ed.Engl., 62, 2023
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7XQE
| Crystal Structure of human RORgamma (C455E) LBD in complex with compound XY039 | Descriptor: | 2,4-difluoro-N-(1-((4-(trifluoromethyl)benzyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide, ETHANOL, GLYCEROL, ... | Authors: | Wu, X, Li, C, Zhang, Y, Xu, Y. | Deposit date: | 2022-05-07 | Release date: | 2023-05-31 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as ROR gamma inverse agonists against prostate cancer. Acta Pharmacol.Sin., 2024
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6J1L
| Crystal Structure Analysis of the ROR gamma(C455E) | Descriptor: | 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide, Nuclear receptor ROR-gamma | Authors: | zhang, Y, Li, C.C, wu, X.S. | Deposit date: | 2018-12-28 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer. J.Med.Chem., 62, 2019
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6KKH
| Crystal structure of the oxalate bound malyl-CoA lyase from Roseiflexus castenholzii | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HpcH/HpaI aldolase, MAGNESIUM ION, ... | Authors: | Tang, W.R, Wang, Z.G, Zhang, C.Y, Wang, C. | Deposit date: | 2019-07-25 | Release date: | 2019-09-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | The C-terminal domain conformational switch revealed by the crystal structure of malyl-CoA lyase from Roseiflexus castenholzii. Biochem.Biophys.Res.Commun., 518, 2019
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6KIN
| Crystal structure of the tri-functional malyl-CoA lyase from Roseiflexus castenholzii | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HpcH/HpaI aldolase | Authors: | Tang, W.R, Zhang, C.Y, Wang, C, Xu, X.L. | Deposit date: | 2019-07-19 | Release date: | 2019-09-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.527 Å) | Cite: | The C-terminal domain conformational switch revealed by the crystal structure of malyl-CoA lyase from Roseiflexus castenholzii. Biochem.Biophys.Res.Commun., 518, 2019
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3E73
| Crystal Structure of Human LanCL1 complexed with GSH | Descriptor: | GLUTATHIONE, LanC-like protein 1, ZINC ION | Authors: | Zhang, W, Zhu, G, Li, X, Rao, Z, Zhang, C. | Deposit date: | 2008-08-17 | Release date: | 2009-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione Genes Dev., 23, 2009
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3E6U
| Crystal structure of Human LanCL1 | Descriptor: | LanC-like protein 1, ZINC ION | Authors: | Zhang, W, Zhu, G, Li, X, Rao, Z, Zhang, C. | Deposit date: | 2008-08-16 | Release date: | 2009-06-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione Genes Dev., 23, 2009
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4NI9
| Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025), FORM 2 | Descriptor: | Interleukin-6, SODIUM ION, SOMAmer SL1025 | Authors: | Davies, D, Edwards, T, Gelinas, A, Jarvis, T, Clifton, M.C. | Deposit date: | 2013-11-05 | Release date: | 2014-01-22 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand. J.Biol.Chem., 289, 2014
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6N33
| Crystal structure of fms kinase domain with a small molecular inhibitor, PLX5622 | Descriptor: | 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor | Authors: | Zhang, Y. | Deposit date: | 2018-11-14 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model. Nat Commun, 10, 2019
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4NI7
| Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025) | Descriptor: | Interleukin-6, SODIUM ION, SOMAmer SL1025 | Authors: | Davies, D, Edwards, T, Gelinas, A, Jarvis, T, Clifton, M.C. | Deposit date: | 2013-11-05 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand. J.Biol.Chem., 289, 2014
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4PW2
| Crystal structure of D-glucuronyl C5 epimerase | Descriptor: | CITRIC ACID, D-glucuronyl C5 epimerase B | Authors: | Ke, J, Qin, Y, Gu, X, Brunzelle, J.S, Xu, H.E, Ding, K. | Deposit date: | 2014-03-18 | Release date: | 2015-01-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Study of d-Glucuronyl C5-epimerase. J.Biol.Chem., 290, 2015
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4PXQ
| Crystal structure of D-glucuronyl C5-epimerase in complex with heparin hexasaccharide | Descriptor: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, D-glucuronyl C5 epimerase B | Authors: | Ke, J, Qin, Y, Gu, X, Tan, J, Brunzelle, J.S, Xu, H.E, Ding, K. | Deposit date: | 2014-03-24 | Release date: | 2015-01-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Functional Study of d-Glucuronyl C5-epimerase. J.Biol.Chem., 290, 2015
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