7CKG
 
 | | Crystal structure of TMSiPheRS complexed with TMSiPhe | | Descriptor: | 4-(trimethylsilyl)-L-phenylalanine, Tyrosine--tRNA ligase | | Authors: | Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P. | | Deposit date: | 2020-07-17 | | Release date: | 2021-03-31 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.053 Å) | | Cite: | DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe.
Nat Commun, 11, 2020
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7X2C
 | | Cryo-EM structure of the fenoldopam-bound D1 dopamine receptor and mini-Gs complex | | Descriptor: | (1R)-6-chloranyl-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | | Authors: | Teng, X, Zheng, S. | | Deposit date: | 2022-02-25 | | Release date: | 2022-06-29 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Ligand recognition and biased agonism of the D1 dopamine receptor.
Nat Commun, 13, 2022
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7X2D
 | | Cryo-EM structure of the tavapadon-bound D1 dopamine receptor and mini-Gs complex | | Descriptor: | 1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxy-phenyl]pyrimidine-2,4-dione, CHOLESTEROL, D(1A) dopamine receptor, ... | | Authors: | Teng, X, Zheng, S. | | Deposit date: | 2022-02-25 | | Release date: | 2022-06-15 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Ligand recognition and biased agonism of the D1 dopamine receptor.
Nat Commun, 13, 2022
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7X2F
 | | Cryo-EM structure of the dopamine and LY3154207-bound D1 dopamine receptor and mini-Gs complex | | Descriptor: | 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ... | | Authors: | Teng, X, Zheng, S. | | Deposit date: | 2022-02-25 | | Release date: | 2022-06-15 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Ligand recognition and biased agonism of the D1 dopamine receptor.
Nat Commun, 13, 2022
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8XDA
 | | Cryo-EM structure of urea bound human urea transporter A2. | | Descriptor: | UREA, Urea transporter 2 | | Authors: | Huang, S, Liu, L, Sun, J, Zhizheng, H. | | Deposit date: | 2023-12-10 | | Release date: | 2024-12-04 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Nat Commun, 15, 2024
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8XDH
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8XDF
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8XD9
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8XDG
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8XDE
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8XDD
 | | Cryo-EM structure of human urea transporter A2. | | Descriptor: | 1-(3-methoxyphenyl)methanamine, 8-hydroxyquinoline-2-carboxylic acid, Urea transporter 2 | | Authors: | Huang, S, Liu, L, Sun, J. | | Deposit date: | 2023-12-10 | | Release date: | 2024-12-04 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Nat Commun, 15, 2024
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7CDW
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8ZUF
 | | Cryo-EM structure of P.nat ACE2 mutant in complex with MOW15-22 RBD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | Authors: | Tang, J, Deng, Z. | | Deposit date: | 2024-06-09 | | Release date: | 2025-02-12 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses.
Cell, 188, 2025
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2ZGG
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6A85
 | | Crystal structure of a novel DNA quadruplex | | Descriptor: | AMMONIUM ION, DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*GP*GP*GP*TP*GP*CP*GP*TP*T)-3'), LEAD (II) ION, ... | | Authors: | Liu, H.H, Gan, J.H. | | Deposit date: | 2018-07-06 | | Release date: | 2019-03-06 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | High-resolution DNA quadruplex structure containing all the A-, G-, C-, T-tetrads.
Nucleic Acids Res., 46, 2018
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5ZX9
 | | Crystal structure of apo form fibronectin-binding protein Apa from Mycobacterium tuberculosis | | Descriptor: | Alanine and proline-rich secreted protein Apa, GLYCEROL | | Authors: | Gao, J, Liu, W.D, Chen, C.C, Guo, R.T. | | Deposit date: | 2018-05-18 | | Release date: | 2019-05-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Functional and structural investigations of fibronectin-binding protein Apa from Mycobacterium tuberculosis.
Biochim Biophys Acta Gen Subj, 1863, 2019
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2ZGD
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5ZXA
 | | Crystal structure of fibronectin-binding protein Apa mutant from Mycobacterium tuberculosis | | Descriptor: | Alanine and proline-rich secreted protein Apa, GLYCEROL, MERCURY (II) ION | | Authors: | Gao, J, Liu, W.D, Chen, C.C, Guo, R.T. | | Deposit date: | 2018-05-18 | | Release date: | 2019-05-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Functional and structural investigations of fibronectin-binding protein Apa from Mycobacterium tuberculosis.
Biochim Biophys Acta Gen Subj, 1863, 2019
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7DK0
 | | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MW05 heavy chain, MW05 light chain, ... | | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | | Deposit date: | 2020-11-22 | | Release date: | 2021-06-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.199 Å) | | Cite: | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Commun Biol, 5, 2022
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7DJZ
 | | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ... | | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | | Deposit date: | 2020-11-22 | | Release date: | 2021-06-09 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.397 Å) | | Cite: | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Commun Biol, 5, 2022
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7ZC1
 | | Subtomogram averaging of Rubisco from Cyanobium carboxysome | | Descriptor: | Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase, small subunit | | Authors: | Ni, T, Zhu, Y, Seaton-Burn, W, Zhang, P. | | Deposit date: | 2022-03-25 | | Release date: | 2022-07-06 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure and assembly of cargo Rubisco in two native alpha-carboxysomes.
Nat Commun, 13, 2022
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7XNX
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7XNY
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6IJ1
 | | Crystal structure of a protein from Actinoplanes | | Descriptor: | ACETATE ION, IMIDAZOLE, Prenylcyclase | | Authors: | Yang, Z.Z, Zhang, L.L, Liu, W.D, Chen, C.C, Guo, R.T. | | Deposit date: | 2018-10-08 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.521 Å) | | Cite: | Crystal structure of TchmY from Actinoplanes teichomyceticus.
Acta Crystallogr.,Sect.F, 75, 2019
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6JCN
 | | Yeast dehydrodolichyl diphosphate synthase complex subunit NUS1 | | Descriptor: | Dehydrodolichyl diphosphate synthase complex subunit NUS1, SULFATE ION | | Authors: | Ko, T.-P, Ma, J, Liu, W, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2019-01-29 | | Release date: | 2019-06-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.998 Å) | | Cite: | Structural insights to heterodimeric cis-prenyltransferases through yeast dehydrodolichyl diphosphate synthase subunit Nus1.
Biochem.Biophys.Res.Commun., 515, 2019
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