4O08
| |
4NZZ
| |
8F8Y
| PHF2 (PHD+JMJ) in Complex with VRK1 N-Terminal Peptide | Descriptor: | 1,2-ETHANEDIOL, Lysine-specific demethylase PHF2, SULFATE ION, ... | Authors: | Horton, J.R, Cheng, X. | Deposit date: | 2022-11-22 | Release date: | 2023-01-18 | Last modified: | 2023-02-08 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2. J.Biol.Chem., 299, 2022
|
|
8F8Z
| |
7W5L
| The crystal structure of the oxidized form of Gluconobacter oxydans WSH-004 SNDH | Descriptor: | L-sorbosone dehydrogenase, NAD(P) dependent | Authors: | Li, D, Hou, X.D, Rao, Y.J, Zhou, J.W, Chen, J. | Deposit date: | 2021-11-30 | Release date: | 2023-01-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
|
|
7W5N
| The crystal structure of the reduced form of Gluconobacter oxydans WSH-004 SNDH | Descriptor: | L-sorbosone dehydrogenase, NAD(P) dependent, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Li, D, Hou, X.D, Rao, Y.J, Yin, D.J, Zhou, J.W, Chen, J. | Deposit date: | 2021-11-30 | Release date: | 2023-03-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.988 Å) | Cite: | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
|
|
5HNE
| X-RAY CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A 2-ARYL BENZIMIDAZOLE COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR | Descriptor: | 1,2-ETHANEDIOL, 1-[(1R,3S)-3-{[(5-bromothiophen-2-yl)carbonyl]amino}cyclohexyl]-N-methyl-2-(pyridin-2-yl)-1H-benzimidazole-5-carboxamide, Branched-chain-amino-acid aminotransferase, ... | Authors: | Somers, D.O. | Deposit date: | 2016-01-18 | Release date: | 2016-05-04 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors. Acs Med.Chem.Lett., 7, 2016
|
|
1Y4K
| Lipoxygenase-1 (Soybean) at 100K, N694G Mutant | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, FE (II) ION, ... | Authors: | Chruszcz, M, Segraves, E, Holman, T.R, Minor, W. | Deposit date: | 2004-12-01 | Release date: | 2005-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Kinetic, spectroscopic, and structural investigations of the soybean lipoxygenase-1 first-coordination sphere mutant, Asn694Gly. Biochemistry, 45, 2006
|
|
2OCI
| Crystal structure of valacyclovir hydrolase complexed with a product analogue | Descriptor: | L-TYROSINAMIDE, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Lai, L, Xu, Z, Amidon, G.L. | Deposit date: | 2006-12-20 | Release date: | 2008-02-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J.Biol.Chem., 283, 2008
|
|
2OCK
| Crystal structure of valacyclovir hydrolase D123N mutant | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, Valacyclovir hydrolase | Authors: | Lai, L, Xu, Z, Amidon, G.L. | Deposit date: | 2006-12-20 | Release date: | 2008-02-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J.Biol.Chem., 283, 2008
|
|
2OCL
| Crystal structure of valacyclovir hydrolase S122A mutant | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, Valacyclovir hydrolase | Authors: | Lai, L, Xu, Z, Amidon, G.L. | Deposit date: | 2006-12-20 | Release date: | 2008-02-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J.Biol.Chem., 283, 2008
|
|
8G05
| Cryo-EM structure of an orphan GPCR-Gi protein signaling complex | Descriptor: | 6-(octylamino)pyrimidine-2,4(3H,5H)-dione, CHOLESTEROL, G-protein coupled receptor 84, ... | Authors: | Zhang, X, Wang, Y.J, Li, X, Liu, G.B, Gong, W.M, Zhang, C. | Deposit date: | 2023-01-31 | Release date: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Pro-phagocytic function and structural basis of GPR84 signaling. Nat Commun, 14, 2023
|
|
2OCG
| Crystal structure of human valacyclovir hydrolase | Descriptor: | GLYCEROL, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Lai, L, Xu, Z, Amidon, G.L. | Deposit date: | 2006-12-20 | Release date: | 2008-02-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J.Biol.Chem., 283, 2008
|
|
2ONO
| |
2ONM
| Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with NAD+ | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aldehyde dehydrogenase, ... | Authors: | Larson, H.N, Hurley, T.D. | Deposit date: | 2007-01-24 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282, 2007
|
|
2ONN
| |
2ONP
| Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, complexed with NAD+ | Descriptor: | 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GUANIDINE, ... | Authors: | Larson, H.N, Hurley, T.D. | Deposit date: | 2007-01-24 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282, 2007
|
|
8I1V
| The asymmetric unit of P22 procapsid | Descriptor: | Major capsid protein, Scaffolding protein | Authors: | Xiao, H, Liu, H.R, Cheng, L.P. | Deposit date: | 2023-01-13 | Release date: | 2023-03-08 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures. Viruses, 15, 2023
|
|
8I1T
| The asymmetric unit of P22 empty capsid | Descriptor: | Major capsid protein | Authors: | Xiao, H, Liu, H.R, Cheng, L.P. | Deposit date: | 2023-01-13 | Release date: | 2023-03-08 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures. Viruses, 15, 2023
|
|
8HWS
| The complex structure of Omicron BA.4 RBD with BD604, S309, and S304 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD-604 Fab Heavy chain, BD-604 Fab Light chain, ... | Authors: | He, Q.W, Xu, Z.P, Xie, Y.F. | Deposit date: | 2023-01-02 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.36 Å) | Cite: | An updated atlas of antibody evasion by SARS-CoV-2 Omicron sub-variants including BQ.1.1 and XBB. Cell Rep Med, 4, 2023
|
|
8HWT
| |
8I99
| N-carbamoyl-D-amino-acid hydrolase mutant - M4Th3 | Descriptor: | N-carbamoyl-D-amino-acid hydrolase | Authors: | Hu, J.M, Ni, Y, Xu, G.C. | Deposit date: | 2023-02-06 | Release date: | 2023-03-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Engineering the Thermostability of a d-Carbamoylase Based on Ancestral Sequence Reconstruction for the Efficient Synthesis of d-Tryptophan. J.Agric.Food Chem., 71, 2023
|
|
8JAN
| |
8JAJ
| |
7DL3
| The structure of 3,5-DAHDHcca complex with NADPH | Descriptor: | 3,5-diaminohexanoate dehydrogenase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | Deposit date: | 2020-11-25 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.84606934 Å) | Cite: | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|