5V6H
 
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6Z2X
 | | Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP (State II) | | Descriptor: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Yates, L.A, Zhang, X. | | Deposit date: | 2020-05-18 | | Release date: | 2020-11-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
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7WHK
 | | The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2021-12-30 | | Release date: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
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7WHI
 | | The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2021-12-30 | | Release date: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
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7WHJ
 | | The state 1 complex structure of Omicron spike with Bn03 (1-up RBD, 3 nanobodies) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2021-12-30 | | Release date: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
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5V6E
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5V6T
 | | The Plexin D1 intracellular region in complex with GIPC1 | | Descriptor: | PDZ domain-containing protein GIPC1, Plexin-D1, SULFATE ION | | Authors: | Shang, G, Zhang, X. | | Deposit date: | 2017-03-17 | | Release date: | 2017-05-31 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.189 Å) | | Cite: | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.
Elife, 6, 2017
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5V6B
 | | Crystal structure of GIPC1 | | Descriptor: | PDZ domain-containing protein GIPC1 | | Authors: | Shang, G, Zhang, X. | | Deposit date: | 2017-03-16 | | Release date: | 2017-05-31 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.
Elife, 6, 2017
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7WZ2
 | | SARS-CoV-2 (D614G) Spike trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-02-16 | | Release date: | 2022-07-20 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
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7WZ1
 | | SARS-CoV-2 Omicron Spike trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-02-16 | | Release date: | 2022-07-27 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
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8DOL
 | | Mechanism of regulation of the Helicobacter pylori Cagbeta ATPase by CagZ | | Descriptor: | Cag pathogenicity island protein (Cag5), DI(HYDROXYETHYL)ETHER, SULFATE ION | | Authors: | Wu, X, Zhao, Y, Yang, W, Sun, L, Ye, X, Jiang, M, Wang, Q, Wang, Q, Zhang, X, Wu, Y. | | Deposit date: | 2022-07-13 | | Release date: | 2023-02-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mechanism of regulation of the Helicobacter pylori Cag beta ATPase by CagZ.
Nat Commun, 14, 2023
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1BR0
 | | THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A | | Descriptor: | PROTEIN (SYNTAXIN 1-A) | | Authors: | Fernandez, I, Ubach, J, Dubulova, I, Zhang, X, Sudhof, T.C, Rizo, J. | | Deposit date: | 1998-08-25 | | Release date: | 1998-09-02 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A.
Cell(Cambridge,Mass.), 94, 1998
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190D
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8HSY
 | | Acyl-ACP Synthetase structure | | Descriptor: | Acyl-acyl carrier protein synthetase | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2022-12-20 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (2.53 Å) | | Cite: | Acyl-ACP Synthetase structure
To Be Published
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8QOT
 | | Structure of the mu opioid receptor bound to the antagonist nanobody NbE | | Descriptor: | Anti-Fab Nanobody, Mu-type opioid receptor, NabFab HC, ... | | Authors: | Yu, J, Kumar, A, Zhang, X, Martin, C, Raia, P, Manglik, A, Ballet, S, Boland, A, Stoeber, M. | | Deposit date: | 2023-09-29 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural Basis of mu-Opioid Receptor-Targeting by a Nanobody Antagonist.
Biorxiv, 2023
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1BM6
 | | SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN STROMELYSIN-1 COMPLEXED TO A POTENT NON-PEPTIDIC INHIBITOR, NMR, 20 STRUCTURES | | Descriptor: | 1-METHYLOXY-4-SULFONE-BENZENE, 3-METHYLPYRIDINE, CALCIUM ION, ... | | Authors: | Li, Y, Zhang, X, Melton, R, Ganu, V, Gonnella, N.C. | | Deposit date: | 1998-07-29 | | Release date: | 1999-07-29 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the catalytic domain of human stromelysin-1 complexed to a potent, nonpeptidic inhibitor.
Biochemistry, 37, 1998
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1C76
 | | STAPHYLOKINASE (SAK) MONOMER | | Descriptor: | STAPHYLOKINASE | | Authors: | Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y. | | Deposit date: | 2000-02-01 | | Release date: | 2000-08-01 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal Structure of Staphylokinase Dimer Offers New Clue to Reduction of Immunogenicity
To be published
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7WOB
 | | SARS-CoV-2 Spike in complex with IgG 553-60 (2-up trimer) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, mAb60 VH, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-21 | | Release date: | 2022-07-20 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
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7WOG
 | | SARS-CoV-2 Omicron S monomer complexed with 553-49 | | Descriptor: | 553-49 VH, 553-49 VL, Spike protein S1 | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-21 | | Release date: | 2022-07-20 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (4.06 Å) | | Cite: | Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
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7WO4
 | | SARS-CoV-2 Spike in complex with IgG 553-15 (S-553-15 dimer trimer ) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, mAb15 VH, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-20 | | Release date: | 2022-07-20 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (4.47 Å) | | Cite: | Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
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7WO7
 | | Locally refined region of SARS-CoV-2 Spike in complex with IgG 553-15 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, mAb15 VH, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-20 | | Release date: | 2022-07-20 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
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7WO5
 | | SARS-CoV-2 Spike in complex with IgG 553-15 (S-553-15 trimer) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, mAb15 VH, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-20 | | Release date: | 2022-07-20 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
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7WOC
 | | Locally refined region of SARS-CoV-2 Spike in complex with IgG 553-60 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, mAb60 VH, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-21 | | Release date: | 2022-07-20 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
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7WOA
 | | SARS-CoV-2 Spike in complex with IgG 553-60 (1-up trimer) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, mAb60 VH, ... | | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2022-01-21 | | Release date: | 2022-07-20 | | Last modified: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
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8I22
 | | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester | | Descriptor: | 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-13 | | Release date: | 2024-01-17 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.15 Å) | | Cite: | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester
To Be Published
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