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5NMU
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BU of 5nmu by Molmil
Structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria
Descriptor: CBS-CP12, CHLORIDE ION
Authors:Hackenberg, C, Hakanpaa, J, Antonyuk, S.V, Dittmann, E, Lamzin, V.S.
Deposit date:2017-04-07
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8T1P
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BU of 8t1p by Molmil
Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ADPVi: BmrCD_OC-ADPVi
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, ...
Authors:Tang, Q, Mchaourab, H.S.
Deposit date:2023-06-02
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8SZC
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BU of 8szc by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-1HT/ATP
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2023-05-29
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8T3K
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BU of 8t3k by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP2
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2023-06-07
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
5NVD
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BU of 5nvd by Molmil
Crystal structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria at 2.5 A resolution in P6322 crystal form
Descriptor: CBS-CP12
Authors:Hackenberg, C, Hakanpaa, J, Eigner, C, Antonyuk, S.V, Dittmann, E, Lamzin, V.S.
Deposit date:2017-05-04
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HSJ
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BU of 6hsj by Molmil
Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA
Descriptor: ACETATE ION, COENZYME A, GLYCEROL, ...
Authors:Wierenga, R.K, Kiema, T.R, Thapa, C.J.
Deposit date:2018-10-01
Release date:2019-01-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
7ZSC
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BU of 7zsc by Molmil
Crystal structure of the heterodimeric human C-P4H-II with truncated alpha subunit (C-P4H-II delta281)
Descriptor: Prolyl 4-hydroxylase subunit alpha-2, Protein disulfide-isomerase, SULFATE ION
Authors:Lebedev, A, Koski, M.K, Wierenga, R.K, Murthy, A.V, Sulu, R.
Deposit date:2022-05-06
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H alpha 2 beta 2 tetramer.
J.Biol.Chem., 298, 2022
6HRV
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BU of 6hrv by Molmil
Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1)
Descriptor: ACETATE ION, GLYCEROL, SCP2-thiolase (type-1)
Authors:Wierenga, R.K, Kiema, T.R, Thapa, C.J.
Deposit date:2018-09-28
Release date:2019-01-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
6HSP
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BU of 6hsp by Molmil
Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA and octanoyl-CoA
Descriptor: COENZYME A, GLYCEROL, OCTANOYL-COENZYME A, ...
Authors:Wierenga, R.K, Kiema, T.R, Thapa, C.J.
Deposit date:2018-10-01
Release date:2019-01-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.
Biochem. J., 476, 2019
4NUT
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BU of 4nut by Molmil
Crystal structure of the complex between Snu13p and the PEP domain of Rsa1
Descriptor: 13 kDa ribonucleoprotein-associated protein, Ribosome assembly 1 protein, SULFATE ION
Authors:Charron, C, Chagot, M.E, Manival, X, Branlant, C, Charpentier, B.
Deposit date:2013-12-04
Release date:2014-12-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control
J.Cell Biol., 207, 2014
4OVU
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BU of 4ovu by Molmil
Crystal Structure of p110alpha in complex with niSH2 of p85alpha
Descriptor: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M.
Deposit date:2014-01-14
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Structural basis of nSH2 regulation and lipid binding in PI3K alpha.
Oncotarget, 5, 2014
1YTM
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BU of 1ytm by Molmil
Crystal structure of phosphoenolpyruvate carboxykinase of Anaerobiospirillum succiniciproducens complexed with ATP, oxalate, magnesium and manganese ions
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Delbaere, L.T.J, Cotelesage, J.J.H.
Deposit date:2005-02-10
Release date:2006-01-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Anaerobiospirillum succiniciproducens PEP carboxykinase reveals an important active site loop
Int.J.Biochem.Cell Biol., 37, 2005
3R8A
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BU of 3r8a by Molmil
X-ray crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a compound with dual PPAR gamma agonism and Angiotensin II Type I receptor antagonism activity
Descriptor: 2-ethyl-5,7-dimethyl-3-{(1S)-5-[2-(1H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl}-3H-imidazo[4,5-b]pyridine, Peroxisome proliferator-activated receptor gamma
Authors:Ohren, J.F.
Deposit date:2011-03-23
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Discovery of a Series of Imidazo[4,5-b]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-gamma.
J.Med.Chem., 54, 2011
1ALD
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BU of 1ald by Molmil
ACTIVITY AND SPECIFICITY OF HUMAN ALDOLASES
Descriptor: ALDOLASE A
Authors:Watson, H.C.
Deposit date:1991-05-05
Release date:1992-01-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Activity and specificity of human aldolases.
J.Mol.Biol., 219, 1991
4TPY
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BU of 4tpy by Molmil
High throughput screening using acoustic droplet ejection to combine protein crystals and chemical libraries on crystallization plates at high density
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BENZAMIDINE, ...
Authors:Teplitsky, E, Joshi, K, Mullen, J.D, Soares, A.S.
Deposit date:2014-06-10
Release date:2014-10-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High throughput screening using acoustic droplet ejection to combine protein crystals and chemical libraries on crystallization plates at high density.
J.Struct.Biol., 191, 2015
2B53
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BU of 2b53 by Molmil
Human cyclin dependent kinase 2 (CDK2) complexed with DIN-234325
Descriptor: 6-(3-AMINOPHENYL)-N-(TERT-BUTYL)-2-(TRIFLUOROMETHYL)QUINAZOLIN-4-AMINE, Cell division protein kinase 2
Authors:Muckelbauer, J.
Deposit date:2005-09-27
Release date:2005-10-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Quinazolines as Cyclin Dependent Kinase Inhibitors
Bioorg.Med.Chem.Lett., 11, 2001
2B54
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BU of 2b54 by Molmil
Human cyclin dependent kinase 2 (CKD2)complexed with DIN-232305
Descriptor: 6-(3,4-DIHYDROXYBENZYL)-3-ETHYL-1-(2,4,6-TRICHLOROPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE, Cell division protein kinase 2
Authors:Chang, C.-C.
Deposit date:2005-09-27
Release date:2005-10-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1h-pyraxolo[3,4-d]pyrimidin-4-one inhibitors of cyclin dependent kinases
J.Med.Chem., 47, 2004
2FBO
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BU of 2fbo by Molmil
Crystal Structure of the Two Tandem V-type Regions of VCBP3 (v-region-containing chitin binding protein) to 1.85 A
Descriptor: variable region-containing chitin-binding protein 3
Authors:Hernandez Prada, J.A, Haire, R.N, Jakoncic, J, Cannon, J.P, Litman, G.W, Ostrov, D.A.
Deposit date:2005-12-09
Release date:2006-10-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus
Nat.Immunol., 7, 2006
2WGP
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BU of 2wgp by Molmil
Crystal structure of human dual specificity phosphatase 14
Descriptor: DUAL SPECIFICITY PROTEIN PHOSPHATASE 14, PHOSPHATE ION
Authors:Lountos, G.T, Tropea, J.E, Cherry, S, Waugh, D.S.
Deposit date:2009-04-22
Release date:2009-10-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Overproduction, Purification and Structure Determination of Human Dual-Specificity Phosphatase 14.
Acta Crystallogr.,Sect.D, 65, 2009
1HAV
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BU of 1hav by Molmil
HEPATITIS A VIRUS 3C PROTEINASE
Descriptor: CHLORIDE ION, HEPATITIS A VIRUS 3C PROTEINASE
Authors:Bergmann, E.M, James, M.N.G.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition.
J.Virol., 71, 1997
4LZZ
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BU of 4lzz by Molmil
Nucleotide-induced asymmetry within atpase activator ring drives s54-RNAP interaction and ATP hydrolysis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transcriptional regulator (NtrC family), ...
Authors:Sysoeva, T.A, Chowdhury, S, Guo, L, Nixon, B.T.
Deposit date:2013-08-01
Release date:2013-12-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Nucleotide-induced asymmetry within ATPase activator ring drives sigma 54-RNAP interaction and ATP hydrolysis.
Genes Dev., 27, 2013
4ALD
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BU of 4ald by Molmil
HUMAN MUSCLE FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE COMPLEXED WITH FRUCTOSE 1,6-BISPHOSPHATE
Descriptor: 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), FRUCTOSE-BISPHOSPHATE ALDOLASE
Authors:Dalby, A.R, Dauter, Z, Littlechild, J.A.
Deposit date:1998-07-26
Release date:1999-03-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications.
Protein Sci., 8, 1999
2ALD
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BU of 2ald by Molmil
HUMAN MUSCLE ALDOLASE
Descriptor: FRUCTOSE-BISPHOSPHATE ALDOLASE
Authors:Dalby, A.R, Littlechild, J.A.
Deposit date:1998-10-21
Release date:1999-04-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications.
Protein Sci., 8, 1999

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