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5SVL
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BU of 5svl by Molmil
Crystal structure of the ATP-gated human P2X3 ion channel in the ATP-bound, closed (desensitized) state
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E.
Deposit date:2016-08-06
Release date:2016-10-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVS
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BU of 5svs by Molmil
Anomalous Mn2+ signal reveals a divalent cation-binding site in the head domain of the ATP-gated human P2X3 ion channel
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ...
Authors:Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.025 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5U4J
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BU of 5u4j by Molmil
Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S12, ...
Authors:Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H.
Deposit date:2016-12-04
Release date:2017-01-11
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
5U4I
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BU of 5u4i by Molmil
Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H.
Deposit date:2016-12-04
Release date:2017-01-11
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
1LDF
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BU of 1ldf by Molmil
CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) MUTATION W48F, F200T
Descriptor: GLYCEROL, Glycerol uptake facilitator protein, MAGNESIUM ION, ...
Authors:Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
1LDA
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BU of 1lda by Molmil
CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL
Descriptor: Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside
Authors:Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
1LDI
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BU of 1ldi by Molmil
CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL
Descriptor: Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside
Authors:Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
6RHY
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BU of 6rhy by Molmil
Structure of pore-forming amyloid-beta tetramers
Descriptor: Amyloid beta A4 protein
Authors:Bardiaux, B, Ciudad, S, Carulla, N.
Deposit date:2019-04-23
Release date:2019-09-25
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A beta (1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage.
Nat Commun, 11, 2020
8T1P
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BU of 8t1p by Molmil
Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ADPVi: BmrCD_OC-ADPVi
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, ...
Authors:Tang, Q, Mchaourab, H.S.
Deposit date:2023-06-02
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8SZC
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BU of 8szc by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-1HT/ATP
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2023-05-29
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
4XI3
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BU of 4xi3 by Molmil
Estrogen Receptor Alpha Ligand Binding Domain in Complex with Bazedoxifene
Descriptor: Bazedoxifene, Estrogen receptor
Authors:Fanning, S.W, Mayne, C.G, Toy, W, Carlson, K, Greene, B, Nowak, J, Walter, R, Panchamukhi, S, Tajhorshid, E, Nettles, K.W, Chandarlapaty, S, Katzenellenbogen, J, Greene, G.L.
Deposit date:2015-01-06
Release date:2016-01-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.491 Å)
Cite:The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.
Elife, 7, 2018
7CUQ
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BU of 7cuq by Molmil
2.55-Angstrom Cryo-EM structure of Cytochrome bo3 from Escherichia coli in Native Membrane
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ...
Authors:Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K.
Deposit date:2020-08-24
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CUW
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BU of 7cuw by Molmil
Ubiquinol Binding Site of Cytochrome bo3 from Escherichia coli
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ...
Authors:Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K.
Deposit date:2020-08-25
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CUB
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BU of 7cub by Molmil
2.55-Angstrom Cryo-EM structure of Cytochrome bo3 from Escherichia coli in Native Membrane
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ...
Authors:Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K.
Deposit date:2020-08-22
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
1Z98
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BU of 1z98 by Molmil
Crystal structure of the spinach aquaporin SoPIP2;1 in a closed conformation
Descriptor: CADMIUM ION, aquaporin
Authors:Tornroth-Horsefield, S, Hedfalk, K, Johanson, U, Karlsson, M, Neutze, R, Kjellbom, P.
Deposit date:2005-04-01
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural mechanism of plant aquaporin gating
Nature, 439, 2006
6D9G
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BU of 6d9g by Molmil
X-ray Structure of the FAB Fragment of 15B8, a Murine Monoclonal Antibody Specific for the Human Serotonin Transporter
Descriptor: Antibody heavy chain Fab, Antibody light chain Fab
Authors:Coleman, J.A, Yang, D, Gouaux, E.
Deposit date:2018-04-29
Release date:2019-04-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
8FMV
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BU of 8fmv by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-2HT/ATP
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2022-12-24
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8FHK
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BU of 8fhk by Molmil
Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ATP: BmrCD_OC-ATP
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2022-12-14
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8VBY
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BU of 8vby by Molmil
Structure of the human dopamine transporter in complex with beta-CFT, MRS7292 and divalent zinc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, DECANE, ...
Authors:Srivastava, D.K, Gouaux, E.
Deposit date:2023-12-12
Release date:2024-08-07
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structure of the human dopamine transporter and mechanisms of inhibition
Nature, 2024
5XLS
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BU of 5xls by Molmil
Crystal structure of UraA in occluded conformation
Descriptor: 12-TUNGSTOPHOSPHATE, URACIL, Uracil permease
Authors:Yu, X.Z, Yang, G.H, Yan, C.Y, Yan, N.
Deposit date:2017-05-11
Release date:2017-07-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters
Cell Res., 27, 2017
7JG1
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BU of 7jg1 by Molmil
Dimeric Immunoglobin A (dIgA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Igh protein, ...
Authors:Kumar Bharathkar, S, Parker, B.P, Malyutin, A.G, Stadtmueller, B.M.
Deposit date:2020-07-18
Release date:2020-11-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structures of Secretory and dimeric Immunoglobulin A.
Elife, 9, 2020
7JG2
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BU of 7jg2 by Molmil
Secretory Immunoglobin A (SIgA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Igh protein, ...
Authors:Kumar Bharathkar, S, Parker, B.P, Malyutin, A.G, Stadtmueller, B.M.
Deposit date:2020-07-18
Release date:2020-11-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structures of Secretory and dimeric Immunoglobulin A.
Elife, 9, 2020
8T3K
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BU of 8t3k by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP2
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2023-06-07
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
6WU4
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BU of 6wu4 by Molmil
Structure of the LaINDY-alpha-ketoglutarate complex
Descriptor: DASS family sodium-coupled anion symporter
Authors:Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WTX
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BU of 6wtx by Molmil
Structure of VcINDY in complex with terephthalate
Descriptor: DASS family sodium-coupled anion symporter, SODIUM ION, terephthalic acid
Authors:Sauer, D.B, Marden, J.J, Wang, D.N.
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.92 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020

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