4OM1
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![BU of 4om1 by Molmil](/molmil-images/mine/4om1) | Crystal structure of antibody VRC07-I30Q, G54W, S58N in complex with clade A/E 93TH057 HIV-1 gp120 core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... | Authors: | Kwon, Y.D, Kwong, P.D. | Deposit date: | 2014-01-25 | Release date: | 2014-09-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.131 Å) | Cite: | Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
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4OLU
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![BU of 4olu by Molmil](/molmil-images/mine/4olu) | Crystal structure of antibody VRC07 in complex with clade A/E 93TH057 HIV-1 gp120 core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... | Authors: | Kwon, Y.D, Kwong, P.D. | Deposit date: | 2014-01-25 | Release date: | 2014-09-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
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4OLY
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![BU of 4oly by Molmil](/molmil-images/mine/4oly) | |
4OM0
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![BU of 4om0 by Molmil](/molmil-images/mine/4om0) | |
4OLW
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![BU of 4olw by Molmil](/molmil-images/mine/4olw) | |
4OLX
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![BU of 4olx by Molmil](/molmil-images/mine/4olx) | |
5NFH
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![BU of 5nfh by Molmil](/molmil-images/mine/5nfh) | Trypanosoma brucei methionyl-tRNA synthetase in complex with a quinazolinone inhibitor | Descriptor: | 2-[3-[[4,6-bis(chloranyl)-1~{H}-indol-2-yl]methylamino]propylamino]-3~{H}-quinazolin-4-one, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Robinson, D.A, Eadsforth, T.C, Shepherd, S.M, Torrie, L.S, De Rycker, M, Gilbert, I.H. | Deposit date: | 2017-03-14 | Release date: | 2017-10-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani. ACS Infect Dis, 3, 2017
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4OLV
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5JNY
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![BU of 5jny by Molmil](/molmil-images/mine/5jny) | Crystal Structure of 10E8 Fab | Descriptor: | 10E8 Heavy Chain, 10E8 Light Chain, CHLORIDE ION, ... | Authors: | Ofek, G, Kwong, P. | Deposit date: | 2016-05-01 | Release date: | 2016-07-13 | Method: | X-RAY DIFFRACTION (3.041 Å) | Cite: | Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8. Plos One, 11, 2016
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5JR1
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5JO5
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![BU of 5jo5 by Molmil](/molmil-images/mine/5jo5) | |
4OLZ
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![BU of 4olz by Molmil](/molmil-images/mine/4olz) | |
7M7V
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![BU of 7m7v by Molmil](/molmil-images/mine/7m7v) | Crystal Structure of Mtb Pks13 Thioesterase domain in complex with Compound 6 | Descriptor: | 5-hydroxy-2-(4-hydroxyphenyl)-N-methyl-4-[(2-oxa-6-azaspiro[3.4]octan-6-yl)methyl]-1-benzofuran-3-carboxamide, Polyketide synthase Pks13 | Authors: | Aggarwal, A, Sacchettini, J.C. | Deposit date: | 2021-03-29 | Release date: | 2022-02-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target. J.Med.Chem., 65, 2022
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4DQO
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![BU of 4dqo by Molmil](/molmil-images/mine/4dqo) | Crystal Structure of PG16 Fab in Complex with V1V2 Region from HIV-1 strain ZM109 | Descriptor: | 1FD6-V1V2 scaffold ZM109 HIV-1 strain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG16 Fab Heavy Chain, ... | Authors: | Pancera, M, McLellan, J.S, Kwong, P.D. | Deposit date: | 2012-02-16 | Release date: | 2013-03-06 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.438 Å) | Cite: | Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16. Nat.Struct.Mol.Biol., 20, 2013
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7YXI
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![BU of 7yxi by Molmil](/molmil-images/mine/7yxi) | |
7YXH
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![BU of 7yxh by Molmil](/molmil-images/mine/7yxh) | |
7YXL
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![BU of 7yxl by Molmil](/molmil-images/mine/7yxl) | |
7YXJ
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![BU of 7yxj by Molmil](/molmil-images/mine/7yxj) | Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and 2,4-PDCA | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GH14974p, ... | Authors: | Chowdhury, R, Schofield, C.J. | Deposit date: | 2022-02-16 | Release date: | 2022-04-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans. Sci Rep, 12, 2022
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7YXG
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7YXK
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![BU of 7yxk by Molmil](/molmil-images/mine/7yxk) | |
5V41
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![BU of 5v41 by Molmil](/molmil-images/mine/5v41) | |
5V42
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![BU of 5v42 by Molmil](/molmil-images/mine/5v42) | |
5V3Y
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![BU of 5v3y by Molmil](/molmil-images/mine/5v3y) | |
5V3X
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5V40
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![BU of 5v40 by Molmil](/molmil-images/mine/5v40) | |